Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65849	Indolophenanthridine	GSE92742	NPC	Human	24h	10uM	EID0363

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	ARID5B; NFATC4; SOX13; HIRA; CCNH; CDK2; ZNF589; YAP1; ZNF195; HOXB5; BHLHE41; ELF4; SRCAP; ZNF394; ACTL6A; PCGF1; CEBPB; TCEA1; PPP1R13L; MED15; THRB; NKRF; TRIB3; IRF6; KLF3; CALCOCO1; IRF8; TCF3; TAF5L; HDAC9; MLXIP; HOXB7; CAMTA2; TDP2; ETS1; VDR; PBXIP1; RAD21; HBP1; JUNB; THAP7; CBX7; AHR; ZNF580; MXI1; HES1; ZNF331; ZBED2; GMNN; KLF11; HOXB2; KDM4C; IRF9; PFDN5; NFE2L3; ZFP36L2; AEBP1; SSBP3; CNBP; POU4F1; HOXB6; SMARCB1; LZTR1; CDX1; RORA; ZHX2; TRIM22; CBX4; TAL1; JUP; ECD; PNRC1; TFDP2; JUND; FOXF2; ELK4; STAT6; TERF2; ERBB4; CSDC2; HIC2; FOS; TFAP2A; GATA6; ID3; CEBPD; TRIM29; SP140L; TGFB1; TCF21; SMAD7; MYRF; TRPS1; SOX17; KAT2B; MYBL1; BNC2; ID2; WT1; NR4A2; SNAI2; ERG; CD3D; NFE2; TBX3; PIR; EHF; SSBP2; DNAJC2; CDK7; IFI16; TCEA2; MECOM; ATF3; NR1H2
Down-regulation	166	EZH2; RHOA; PUF60; TBP; TFDP1; SOX11; ZNF189; IKBKAP; RBM14; EDF1; SPDEF; UBE2I; SIX1; ZNF516; MSX1; ENO1; NONO; WHSC1; BATF; RCOR1; PSMC3IP; ZNF711; RBPMS; TRRAP; ZKSCAN7; NELFB; DNAJC1; TSC22D1; FLNA; ZNF146; SIX2; RFX5; ZEB2; BASP1; FOXO3; HMG20A; SFPQ; BMI1; RBBP4; HNRNPD; GABPB1; HMGB3; ADNP2; YBX1; PHF2; USF2; HSF2; TCEB2; ZNF292; MYT1L; TBL1X; RBPJ; NCOA6; BRD8; DDX5; CHAF1B; ZFP64; DPF2; KDM5D; NCOA4; SETD3; NFKBIA; ZNF160; ZNF587; TCF12; MYT1; DNMT3B; JARID2; ARID4B; EYA1; MAGED1; KDM2A; CBFB; BRD3; CBX3; TRIM24; SALL1; IRX5; ZNF551; HDAC2; DDX17; SP3; ATF4; RBBP7; ZNF672; ADNP; NUP62; ASH2L; EGR3; HDAC6; RFX7; CTR9; HMGA2; ZNF177; CARHSP1; BRPF1; BAZ2B; SMARCA2; ZNF532; ZNF721; NKX2-2; EYA2; PLAGL2; BLM; ZNF302; BCOR; ZNF329; VEZF1; MNAT1; KMT2A; ZBTB38; NCOR2; NFIB; BBX; NEDD8; ZNF248; VGLL4; ING3; BAZ1B; INSM1; ELF5; USP22; SMARCA5; PIAS3; NRBF2; PBX1; MXD4; DACH1; CREB5; FOXG1; NR1D2; NCOA3; NFATC1; CHD9; BRCA1; NFE2L2; SOX10; CREB3L1; YWHAB; TRIM28; NAB1; MTF2; NR2F2; SCAND1; BCL11B; IRF4; CHD7; ERBB2; TCF4; ASCL1; TOX3; MYCBP; CRK; RBBP8; TCFL5; MED13; SIAH2; MEF2A; HEY1; DMTF1; CEBPZ; EED; NFATC3; NFIL3; NFKBIB; EGR1