Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65805	Spiperone	GSE92742	NPC	Human	24h	10uM	EID0363

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	IRF6; PFDN5; ELF5; ZNF507; ZNF589; HMGXB3; HIRA; OVOL2; EN1; ZNF394; HHEX; TFCP2; ATN1; JUND; SPDEF; AR; ZNF467; ZNF652; ZNF593; ZNF580; PRDM2; LHX6; FOXD1; TCEB2; HOXC4; NKX2-1; HOXB5; HEY2; STAT4; GCFC2; TRIM27; TRIM16; ATF5; JUN; KDM5A; ZNF354A; CNOT2; CALR; HLX; SOX10; ZNF165; PBXIP1; ZBTB20; ARID1A; CEBPB; EPAS1; MYRF; TFDP2; PSMC3; MAZ; TRIB3; TCF7L2; TCF7L1; NR1H3; INSR; CSDE1; TCF7; FOXA2; TRPS1; SOX9; IRF9; LMCD1; HMGB3; SOHLH2; MYCL; C1QBP; CD3D; FOS; TFCP2L1; MNDA; FOSB; GATA6; TFAP2A; POU2AF1; ST18; LITAF; ID1; HOXB6; TFAP2C; DLX2; ATF3; MYB; JUP; TCEA2; HOXC6; HMG20B; ESR1
Down-regulation	142	CBX3; SPEN; IKBKAP; USP22; SMAD3; SMARCE1; RBPMS; WDHD1; BRD8; TFAM; PSIP1; ZNF189; ZNF443; HDAC9; SUPT4H1; NFE2L1; TLE1; CREB1; ZNF419; REST; PSMC3IP; PPARGC1A; HOXD1; BCOR; EWSR1; MEIS1; ING2; NUP62; ZNF217; ZZZ3; PEG3; PRKDC; BMI1; RARA; PLAGL2; ACTL6A; VEZF1; SMARCA4; HMG20A; PATZ1; LZTS1; EGR3; BASP1; CHD1; ZSCAN12; PKNOX1; MYT1L; BRCA1; NCOR2; ATF2; CENPF; STAT3; MITF; ZBED1; BRD3; ZNF266; SREBF1; MAML1; CHD3; BCL10; ZNF267; NFYB; NFKB1; RXRA; CDYL; ZNF813; ZBTB11; NCOA2; RBM14; ZNF468; ASH2L; UBE2B; ZNF329; TBPL1; PITX2; EMX2; ING3; PURA; KLF10; NPAS2; DEK; ETV1; HIVEP2; ITGB3BP; TMF1; POU5F1B; NANOG; ZNF12; BLM; SATB2; HMGB2; PMS1; EP300; HLTF; KAT7; BAZ1B; STAT1; ZIC1; MYCBP; RNF6; RB1; BIRC2; EED; ZNF587; ATF4; ZBTB38; SMAD5; FOXJ3; NRIP1; ZEB1; HES1; ETS2; E2F8; NAB1; ZBED2; KLF5; ZMYND8; HLF; ZNF331; HIF1A; GTF2IRD1; DNMT3B; IFI16; FOXF1; EGR2; NFAT5; NR1D2; HMGA2; ZMYM2; MAFB; DACH1; ZFPM2; KLF4; JUNB; TCFL5; CDK7; MED13; TOB1; WT1; SNAI2; MECOM; NR4A2