Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65736	Desmethylclozapine	GSE92742	NPC	Human	24h	10uM	EID0363

Response Information :

Types	Number	Response transcription factors
Up-regulation	303	PPARG; EZH1; DLX5; PAX8; OVOL2; TRRAP; PPARD; HOXA10; TBX2; HMG20A; STAT5B; HIPK3; NFATC4; IL16; IKZF1; MSC; TFE3; KLF2; SIM1; ZBED2; CCNE1; SOX5; EYA2; MITF; STAT4; GATA3; WHSC1L1; TWIST1; TFEC; FOXD1; SREBF2; CHD3; HOXB2; FOXO4; HIF3A; BHLHE40; RELB; PLAGL1; RAX; ZNF556; GBX1; ALX1; PRDM13; PGR; RORC; DLX6; BATF; IRF2; TBX4; MXD1; IRF4; HOXB3; WNT4; JAK2; SMARCA2; KDM5D; THRB; STAT5A; SMARCD3; CRTC1; IFNB1; PIR; SUV39H1; NR3C1; SP140; TXNIP; PITX1; MYBL2; PRMT2; PLAG1; SP1; SIAH2; AFF4; NEUROD1; NR1H3; PDX1; LZTS1; ZBTB7B; VDR; FOSB; KAT5; SREBF1; NFIX; ILF2; ELF3; COPS5; HOXB5; TSC22D4; FOSL1; ATF6; CBX7; TP73; KDM5B; FLI1; SSBP3; EGR3; TLX1; TSC22D3; MYB; ELK1; NCOA1; CDX2; STAT6; GABPB1; CDK2; ZFY; ZNF208; ETV7; TGS1; POU2F2; PRKDC; RNF141; BRF2; PCBD1; GLI3; ZNF507; CCNH; NSD1; BCL11A; PPP1R13L; PKNOX2; CBX5; HDAC7; BAZ1B; HOXA11; HR; NAB1; FUBP1; PRRX2; HOXB1; GFI1; ZNF506; TFAM; TAL1; STAT3; SIN3B; NFKBIA; CALCOCO1; ZSCAN18; VPS72; NFE2L3; MED12; BACH2; FOXO3; SNAI2; THRAP3; NCOA2; GLI1; HTATIP2; SHOX2; PHF8; HLTF; EHF; CARF; SHOX; HOXC8; FOXA2; IRF1; BTAF1; KLF4; GLI2; SMARCA1; CDX1; PRDM2; TBL1X; ZNF580; FOXB1; POU4F1; CENPB; TAF7; NR3C2; TFAP4; ESR1; LMCD1; PBXIP1; ZNF324; TERF2; ARRB1; PBX2; KLF3; HOXD3; HOXC10; ZBTB18; XBP1; CIC; TEAD1; BARX1; FEV; KMT2A; ETS2; TGIF1; FHL2; LZTR1; RB1; SOX21; PHOX2A; CCNT1; KAT2A; THAP11; ZNF331; MDM2; SOX10; CHD7; ATF3; ACTL6A; NFE2L1; KLF5; ID4; HOXA1; FOSL2; BCL10; AEBP1; ASCL1; NFYC; HMGXB4; DDX17; ZNF107; ETS1; CD3D; KDM4C; HMGB2; TRIM22; BRCA1; TLE2; HMGA1; WT1; HDAC6; DBP; FOXE1; RSF1; HBP1; ECD; MED24; CEBPB; ZNF587; CTR9; ELK4; HAND1; AFF1; HOXC6; HOXB6; TP53; WWC1; SNAI1; AR; NLK; YBX2; VGLL1; GTF2I; TBX21; TFDP2; ZNF217; IRF8; ST18; RARA; TFAP2C; SERTAD2; CIITA; ZBTB44; MXI1; ZIC1; PURA; PEX2; CBX6; NFAT5; HDAC1; SOHLH2; CSDE1; HMGB1; MECOM; ATF1; NKX2-1; MEOX2; FOXL2; SMARCA5; RBL2; SOX17; HLF; SSX1; BHLHE41; NFE2L2; ZNF467; TSC22D1; CEBPG; BCL11B; BNC2; TRIM16; ETV1; NFE2; CDK7; KLF9; SUB1; IRF6; GTF2IRD1; ZNF274; BCL3; DMTF1; POU2AF1; IFI16; SMARCD2; PSMD9; NR1H2; EGR1
Down-regulation	347	ZMIZ1; NR2F6; RHOA; TLE1; KAT6B; TRIM24; IKBKAP; ZNF45; ZNF232; SOX11; HMGN3; TULP3; RFX5; MED27; ZNF44; ZNF140; APEX1; NR2F1; PHIP; ZNF573; PAX6; WWTR1; PHF20; PAWR; ZNF426; ZNF189; CNOT2; CCNC; CBX3; HIRA; NONO; ZNF200; PQBP1; ZNF112; ZNF239; TDP2; ADNP2; NFKB2; ZNF263; PRDM4; ZNF551; CITED2; ZNF227; ETV5; HOXD1; ABL1; FLNA; SPEN; TAF11; ZNF419; ZSCAN5A; CDYL; PEX14; CARHSP1; SFPQ; ZNF446; BTF3; PBX1; ATF4; ZNF219; NANOG; ZNF174; ZNF668; ZNF432; EYA1; ZNF764; RCOR1; DACH1; DR1; SALL1; ARID4B; ETV4; ZNF250; BIRC2; MYCN; ZNF184; ZNF84; ZBTB16; MAFB; BTG1; ARID5B; DAXX; ZSCAN16; PRDM10; FOXF2; AHR; CENPF; TOX3; SRF; ZNF611; PSMC3IP; SUPT3H; ZNF35; SNW1; ZNF7; SAP130; LIN28A; TCEB2; ERF; BRD8; THAP10; ZNF544; ING1; SF1; FOXJ3; DNAJC1; RXRA; STAT1; POU3F2; LITAF; ZNF74; ZBED4; CREB1; SNAPC4; ZSCAN12; ZEB1; ADNP; YEATS4; ZNF146; TOX; CNOT1; INSM1; PRDM14; ZNF268; ZNF473; TOX4; MEOX1; MED17; ZNF93; ZNF160; ZFP37; ZZZ3; BRD2; FOXF1; POU5F1B; ZFX; RNF138; ZNF180; VGLL4; HES1; CRY1; ZNF16; NR1H4; HOXA7; RBBP5; RNF4; ZKSCAN5; SCAND1; NKRF; HMGB3; PMS1; CAMTA1; ZNF177; BRD3; YBX3; ZNF131; ZNF468; ZNF155; RLF; JARID2; ZNF124; IRX4; ZNF292; ZFP69B; ZNF85; ZNF423; ZSCAN32; ZNF696; ERCC3; CTBP2; PCGF3; ZNF3; HNRNPD; WWP1; SP2; CHD8; TCF7; BAZ2B; ENY2; NEDD8; REXO4; BRCA2; TCF3; ATF2; ZKSCAN7; ZNF224; ZKSCAN4; SOX9; NRBF2; TRIM32; ZNF669; PSPC1; MYT1; TRIB3; PHF2; ZFP36L1; FOXJ2; ZNF410; KLF7; ZNF329; ZNF197; PTTG1; GATA6; GTF2F1; ZNF430; ZKSCAN3; HDAC3; ID3; RNF111; MEIS2; ZHX2; MYCL; RAN; UBE3A; DPF2; ZNF142; ZNF211; BLZF1; NR0B1; BANP; LOXL2; ZNF557; TAF5L; PIAS4; ZNF721; ZNF350; RFXANK; HIVEP1; ZNF32; SOX15; ITGB3BP; MKL2; TRIM27; E2F3; RREB1; MNT; MED6; CBFA2T2; IRF3; FOXM1; MNAT1; ZMIZ2; REPIN1; PSMC3; ZNF529; NRIP1; SOX3; ID1; TTF1; ZNF302; HHEX; NKX2-2; TAF5; TBX3; ZNF532; EGR2; ERG; HEY1; ZBTB7A; RUVBL2; POLR3C; CUX2; ZNF665; SMARCE1; ERBB2; CREB3; DLX2; PPARGC1A; NR2C1; ZNF91; KDM5A; ZNF12; TEAD4; ING2; ZNF667; TULP4; ZFP64; TGFB1I1; GMNN; FHL5; SALL2; FOXG1; YBX1; ZFP30; ZBED1; CHD9; BRPF1; CREM; ARID3B; SAP30; TCF7L2; ZNF606; CBFB; MTF2; TCF12; INSR; REL; ARL2BP; NPM1; ZNF354A; THAP4; CTCF; BCL6; ZNF148; BRIP1; BCOR; PITX2; RBM39; ZBTB43; IRF9; PROX1; GATAD2A; HDAC4; BMI1; NPAS2; HOXB13; ISL1; OLIG2; HIC2; NKX3-1; CDK9; USP22; NFATC1; E2F6; AES; TGFB1; ZNF281; PAXBP1; ZMYM2; SSBP2; DNMT3B; NFIB; FOS; CEBPZ; C1QBP; LYL1; FOXC1; KAT2B; BASP1; ZFP36L2; OSR2; FOXO1; GATA2; MEIS1; CRK; HOXA5; ZKSCAN1