Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65676	Trimipramine	GSE92742	NPC	Human	24h	10uM	EID0363

Response Information :

Types	Number	Response transcription factors
Up-regulation	311	PPARG; DLX5; CEBPA; HOXA10; PPP1R13L; PPARD; KDM5D; PAX8; FOSL1; STAT5B; MXD1; STAT5A; IFNB1; IKZF1; CREB3L2; ZBTB18; SREBF2; GATA3; FOXO4; NCOA1; HOXC10; BHLHE40; POU2F2; HOXC6; KDM5B; MYB; HOXA11; TSC22D1; BHLHE41; ARID1A; SMAD3; TRRAP; ZNF107; MDM2; PLAGL1; HCFC1; NSD1; MED12; SP1; EZH1; TBL1X; CTR9; NFATC4; MSX1; ZNF556; BATF; RELB; SERTAD2; PGR; KLF2; RORC; AEBP1; ERCC2; ATN1; NR3C1; SPEN; ZNF586; ZNF282; ESR1; ZNF117; NCOA2; WHSC1L1; RUNX1; MYBL2; HIPK3; VDR; MTF1; TSC22D3; PCBD1; LDB1; GABPB1; FOSB; KLF1; NFIX; FOSL2; MYC; GLI3; ASH2L; POU6F1; STAT2; CHD3; ZNF507; SSBP3; RBPJL; ZFY; SOX4; MITF; SIAH2; HNF1B; ZNF324B; THRA; IRF2; PHF8; TXNIP; TRIM25; SP100; DLX6; GFI1; KAT6A; HOXC8; HOXB7; AFF4; HOXB5; BRF2; TSC22D4; ETS2; ZNF783; MXI1; RBPMS; ZNF528; PHF1; PBX2; BCL11A; FOXO3; E2F2; ATF6; AR; STAT3; ZNF273; KMT5A; HLTF; HMX1; HDAC7; NFKB2; KDM2A; TBP; HOXB3; CLOCK; RBBP8; RNF14; SLC2A4RG; ZBED2; CBX5; TAF1C; TFEC; ELF3; IL16; NFKBIA; KLF6; SMARCC2; POLR2A; TFE3; MDM4; MAZ; CALCOCO1; SOX13; HOXB1; TAF7; NFKB1; PURA; WT1; SMARCA2; CXXC1; EHF; ELK1; SMARCA5; HDGF; GLI1; ZNF331; HIVEP2; MED25; TCF7L2; SUPT6H; GLI2; ZNF506; PITX1; MYT1L; HOXB6; SNAI2; MSC; IFI16; ZNF467; SMARCD1; GATA1; ZNF212; SMARCD3; NFAT5; LMCD1; THAP11; SKI; ARID4A; WHSC1; CUX1; TSHZ2; MKL2; ZNF771; CBX6; THRB; RB1; SIM1; ZNF224; PIAS3; FOXJ1; AGO2; XBP1; ZNF165; VPS72; RCOR3; DDX54; PKNOX1; ZNF175; HMBOX1; ZNF574; PRKDC; ZNF443; KMT2D; CCNH; GTF2A2; NR2C1; REL; TAF1; NFE2; SNAI1; GTF2I; HDAC6; MLXIP; FHL2; CBFA2T3; PRRX2; CTNNB1; TP53; HOXB2; ZBTB44; TFDP2; SPDEF; NFE2L2; TAL1; ZFHX4; RBL2; FEV; FOXK2; FOXD1; HSBP1; TFCP2; EGR3; RYBP; PIR; IRF4; TADA3; ECD; BTG1; ZNF580; HIPK1; PHOX2A; ERG; KDM5C; CCNE1; OVOL2; YWHAB; NFIC; KMT2B; FOXL2; ZNF589; BAZ1B; EYA2; MAX; ID4; HMGXB4; HOXC4; PNRC1; CDK7; MGA; HEY1; HTATIP2; FOXA2; ALX1; IRF9; NAB1; CSDE1; DNMT3B; KLF13; KMT2A; ELF5; ATF3; ING2; SP140L; ZNF430; ZSCAN18; HLF; ETS1; ZNF652; TWIST1; ZMIZ2; HOXA5; SMARCA1; MAGED1; HAND1; MYRF; CBX7; MED1; CD3D; ASCL1; SSX1; TGFB1; MAF; BAZ1A; RUNX3; ZNF274; TFAP2A; TOB1; ATF1; MBD2; LEF1; TCEA2; MED13; PSMD9; NFIL3; SMARCD2; NFKBIB; CRK; NR1H2
Down-regulation	287	NR2F6; PSIP1; ZMIZ1; TLE1; SOX11; IKBKAP; ZNF232; MED27; INSM1; LIN28A; PAX6; ATF4; CBX3; RFX5; SNAPC4; HIRA; ZNF239; CUX2; CDYL; MYCN; ZNF263; SOX15; KAT6B; GTF3A; CARHSP1; SALL2; PTTG1; LOXL2; RCOR1; HMGA2; ZNF573; TULP3; ZNF112; RXRA; BASP1; BNC1; PMS1; PQBP1; APEX1; RBFOX2; CDIP1; TDP2; ZBTB3; ARID5B; HOXD11; PHF20; ABL1; ZNF668; HIC2; ZNF219; RNF138; PSMC3IP; XRCC6; FOXN3; ZZZ3; NKX2-2; NANOG; DAXX; WDHD1; ITGB3BP; ZNF189; BRD3; ARID4B; DEK; ZNF74; REXO4; SALL1; IRF8; ZNF532; PIAS4; TAF1A; CREB1; CNBP; LITAF; THAP9; MED4; KLF10; HIVEP1; STAT1; E2F5; ETV5; CENPF; TCF25; ZNF177; SUPT7L; CREBL2; TAF11; TRIM32; TRIM24; CBFB; POU3F2; ZIC3; ZNF500; ZNF432; BIRC2; MED14; EED; EDF1; SAFB2; HOXD1; ZNF571; ZNF423; ZNF146; ZNF174; MYT1; HES1; TOX3; CREB3; CCNC; ZNF131; GATA6; FOXJ3; SAP18; NRBF2; TDRD3; JUNB; ING1; CITED2; SCAND1; MAFB; ZNF764; SAP130; VAX2; CAMTA1; TSG101; PPARGC1A; ETV4; RNF6; CERS4; TCF7; THAP10; HOXB13; SPIB; SIX1; ZBED4; PCGF1; WWP1; NELFB; SFPQ; BLM; TFAM; ZNF23; ING4; ZSCAN16; L3MBTL1; EGR2; PEX14; HCFC2; NONO; ZNF667; ZNF410; VGLL4; LHX2; HNRNPD; PRDM4; PRDM10; THAP1; TAF9; TLE2; SUPT3H; TRIB3; FLNA; SF1; HHEX; NEUROD1; SNW1; ZFP30; UTF1; ZFX; SP2; TOX; PBX1; PCGF3; YEATS4; TAF5; HDAC3; ZSCAN12; RBL1; ZBTB11; BCOR; ZNF200; ZNF202; NRIP1; HMG20B; ING3; BRCA2; DLX2; ZBTB14; ENY2; ZNF557; TCF3; PAWR; FOXO1; SOX3; MTF2; MED17; TAF1D; ZNF227; ZNF140; TFEB; ACTL6A; TCF7L1; HINFP; JARID2; MYCL; PAXBP1; NR1H4; CITED1; LHX1; CHD1; ELK3; ID1; MEOX1; ZNF606; SND1; HDAC9; CEBPB; FOXF2; IRF3; TOX4; ZNF84; SOX9; BACH2; AES; ARL2BP; CHD8; ZEB1; CBFA2T2; TP63; ERBB2; MEOX2; CDC5L; PSPC1; MNAT1; TEAD1; KDM5A; UBE2L3; CTCF; ZFP36L2; ZNF529; RLF; ZNF32; BRPF1; HMGB2; ZBTB1; WWTR1; BRIP1; ELF1; ID3; USP22; DACH1; NR1D2; ETV1; CTBP2; TEAD4; RBBP4; RBM39; TBX3; ERF; PIAS1; SSBP2; ZNF536; ZNF415; FOS; ZNF721; JUP; CEBPZ; PITX2; RAN; SMAD7; BRD2; NFIB; NR0B1; GMNN; DLX4; OLIG2; ISL1; AIP; BCL6; ZNF91; ZMYM2; KLF4; POU2AF1; ZFP36L1; IRF1; MEIS1; MYBL1