Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65558	Norcyclobenzaprine	GSE92742	NPC	Human	24h	10uM	EID0362

Response Information :

Types	Number	Response transcription factors
Up-regulation	63	NR1H2; JUP; E2F8; VPS72; EN1; CNOT3; BHLHE40; ZFP36L2; NR5A2; ZNF117; POLR3C; TRIM24; TSC22D1; IRF9; ACTL6A; ZNF124; CEBPD; TFCP2L1; FOXI1; AHR; ZNF165; ELK3; ZNF273; ZIC1; MED17; AR; MYCL; ST18; RBL2; RCOR1; PNRC1; RAD21; NKX2-2; TRPS1; ZNF85; ZNF574; TCF7L2; ZNF43; TGFB1; LITAF; SSBP2; VDR; TRIM29; ZEB1; HIC2; IRF6; ZNF331; ZSCAN18; KLF13; FOXG1; ZNF91; CHD4; MYB; TLE1; INSM1; ESR1; HDAC9; MNDA; MED6; EHF; NFIB; TFAP2C; CRK
Down-regulation	79	HMG20B; PSMC3IP; ZBTB38; CARM1; EYA1; EDF1; NR2F2; TCEA2; MED24; RAN; TADA3; ING2; BRPF1; PCGF2; PHF8; ASCL1; SP140L; ZNF24; SMARCE1; BAZ2B; NKX3-1; BATF3; GTF2IRD1; CITED2; MAX; CHD7; PAXBP1; PLAG1; PATZ1; BASP1; KDM2A; MTDH; TBL1X; NPAS2; VGLL4; PREB; KDM5D; NFKBIA; JARID2; ZBTB48; FOXF1; TSC22D2; WWC1; BRD8; SIAH2; TCF21; CDK7; TRIP6; HSF2; ETV1; HOXC6; PTTG1; NR2F1; ZNF131; SIX2; FHL2; CREM; SCAND1; BTG1; PHIP; PAX5; ERBB2; ZMYND8; HMGB2; MEIS1; NUP62; HDAC1; AEBP1; FOXJ3; MNAT1; DAXX; SNAI2; PBX3; NFKBIB; TLE4; POU2AF1; NFATC3; PEG3; E2F2