Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65548	Chlorprothixene	GSE92742	NPC	Human	24h	10uM	EID0362

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	MYCN; CEBPD; VDR; TBX2; PCGF1; STAT3; ZBTB16; TP53; FOXJ2; ZNF415; VPS72; ZNF141; SMAD3; E2F8; BHLHE40; ZNF573; CIR1; IRF6; SAP130; TGFB1; ZNF267; KLF13; DLX5; TCF25; SOX13; NFKB2; PNRC1; SP3; MNDA; EHF; ZNF33B; NCOA3; TDRD3; PCGF3; ELF4; NHLH2; MED15; CCNE1; STAT1; SATB2; TLE2; CDX2; ZNF665; ZNF91; MECP2; SOX9; SPI1; HEY1; ZNF423; HOXD1; RNF6; ZNF85; CCNH; CDX1; NFAT5; BHLHE41; ZNF264; MYCL; FOXO1; RUNX3; TSC22D1; MAF; ARID5B; EYA2; KLF9; TULP4; PFDN5; ATF3; IRF9; HIC2; SSBP2; ZNF394; MBD2; SNAI2; SOX17; SHOX2; ZFP36L2; ZNF43; HOXB2; ZFHX3; FOXC1; TRIM22; ZNF124; PIR; ELF5; TRPS1; HOXB6; CHD7; ZNF14; TFAP2C; KLF10; HIRA; BTG1; HTATIP2; TWIST1; MSX1; IFI16; MYBL1; CITED2; ETS1; BRD4; MYB; ESR1; ZKSCAN1; HDAC9; MAFB; ZBTB18; TCEA2; CRK
Down-regulation	109	MYC; TCERG1; RAN; DDX5; CEBPZ; PUF60; SMARCE1; MED1; KAT7; TADA3; SP140L; RBM14; TSC22D2; SOX2; NFIL3; EZH2; MED13; NKX3-1; BCOR; SPDEF; THAP1; PSIP1; PRKDC; PARP1; BPTF; SIM2; PBRM1; PSMC3IP; TAF11; MED24; ELF2; TCF12; BRD8; ASCL1; BRPF1; CARHSP1; SMARCA4; VEZF1; HSF2; HDAC2; SUV39H1; C1QBP; DEK; SSRP1; MYRF; PHF8; KDM2A; SFPQ; ING2; ETV1; EDF1; ID4; ZNF672; ZIC1; UBP1; CDK7; SREBF1; CRY1; PTTG1; NELFB; PREB; SCAND1; NFKBIA; PITX2; BRD2; ERBB2; KAT6A; NCOR2; TFAM; MAGED1; NR2F2; TLE1; SETD2; ARNTL2; ZNF226; BCLAF1; HMGA2; MNAT1; HOXC6; TOX; BRIP1; YEATS4; PEG3; KDM5D; CTBP1; DAXX; KLF2; AEBP1; NUP62; BBX; HMGN3; NR2F1; HOXC10; HHEX; PAWR; DMTF1; PBX3; ZBTB20; JUND; HMGB2; HDAC1; TCF4; TRIM16; TLE4; POU2AF1; NRIP1; BASP1; E2F2; EGR1