Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65146	Pirfenidone	GSE92742	NEU	Human	24h	10uM	EID0360

Response Information :

Types	Number	Response transcription factors
Up-regulation	133	ADRB2; HMGA1; TCFL5; ZNF571; MYCBP; DAXX; IRF6; ZNF239; POLR2A; IRF8; NFKB2; NEUROD1; NR5A2; MED27; TEAD3; TFDP2; E2F6; LHX6; MAX; ANKRD1; ARID5A; ERBB4; AES; PIAS4; SAP130; TGIF1; SOHLH2; ZSCAN5A; SIAH2; CREM; MECOM; HIC2; ZNF335; LIN28A; WNT4; RBL2; SOX18; OSR2; HOXD10; TBX21; AR; ZNF226; ZNF589; THAP7; TGIF2; ZNF345; E4F1; DMRT1; ZNF492; PGR; OLIG2; NAB2; NOC2L; ZNF500; CBFA2T3; CUX2; IRX5; ING4; NKX2-2; NFIB; CALR; JUP; NANOG; KLF1; MYCL; FOSL2; PREB; POLR3C; BANP; MTA2; CRY1; MED15; USP21; RNF14; TFAP2C; BACH1; POU5F1B; GFI1B; YAF2; PAX6; TXNIP; LYL1; NR0B1; SOX10; SSBP3; ID2; ZNF350; HOXA11; SKI; SERTAD2; FOXM1; NCOA1; STAT4; ELK3; HHEX; PEG3; BTG1; FOXE1; HIRA; WT1; CTNNB1; SLC2A4RG; TLE2; RREB1; WWTR1; MEOX1; ESR1; ZFP36L2; CDK9; TBX3; CEBPB; TGFB1; HEY2; KLF2; MNDA; TAL1; MYBL1; DACH1; NFE2; ABL1; ID1; SSX1; NFATC3; SALL1; FOXC1; YBX1; MEOX2; SOX9; MYBL2; TRIM16; PDLIM1; ATF3; HMG20B
Down-regulation	176	USP22; KAT6B; DMTF1; NUP62; BAZ1B; DDX5; EED; CTBP1; BPTF; NCOR2; HIVEP2; MED12; TAF7; BRD7; ZKSCAN1; ETV1; WWC1; YAP1; TLE1; BAZ1A; DDX17; HOXD1; SETD3; KAT2A; PHF8; ASCL1; ZNF337; SUZ12; CIR1; ZMYM2; RAX; INSM1; HOXA4; NCOA2; TULP4; UBE3A; TSC22D3; MLXIPL; TRIM33; TAF1; BASP1; AEBP1; NR2F1; GFI1; RSF1; ZNF783; MDM2; CRK; TTF2; MBD2; TMF1; HOXB1; POU2AF1; SMAD5; CNOT2; HIPK1; CCNA2; PRRX1; BCLAF1; IRF2; HDAC6; IKBKAP; WWP1; L3MBTL1; TOPORS; HAND1; ADNP; ZBED4; MED13; ZNF419; SAP18; ZNF91; SNAI2; ZBTB24; KLF9; NFE2L1; TOX3; BLM; ETS2; MAFF; PSIP1; ZBTB1; EP400; RBFOX2; TAF1D; RRN3; CHD7; LEF1; BCOR; ZMYND11; ZNF264; CTR9; AATF; TAF9; EYA1; NR1D2; MAF; RYBP; ZBTB38; RUNX1; ZNF248; ZNF302; COPS2; MTDH; ZBTB20; ZNF7; ATF2; PROX1; MTF2; RBBP5; CBX5; ZMYND8; ZNF587; VGLL4; MED1; ZNF652; RFC1; SAP30; TAF5; CBFB; PHF2; ZNF611; CHD4; BRD8; BAZ2B; SMAD2; CRYM; PPP1R13L; FOSB; RBM14; HDAC2; VDR; BMI1; HIPK2; ERBB2; KDM5D; ZFHX4; GATA6; TBX2; ZNF721; SATB1; ZNF281; CSDE1; MED6; RBM39; ID4; HLF; KAT7; CERS6; RNF6; PIR; ISL1; SPIB; STAT1; ZNF160; MAGED1; HOXA5; RFX5; HEY1; ZNF83; FOXO1; NFAT5; BNC2; PATZ1; ZBTB18; MYC; MEIS1; FOXD1; ID3; MYB; HOXB7; NCOA3; PBX3; ZIC1; HOXB6; ZBED2