Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65124	Benzonatate	GSE92742	NEU	Human	24h	10uM	EID0360

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	TFCP2L1; HMGA1; CAPN15; WNT4; IRF6; MED20; ZXDC; NFATC1; NEUROD6; ZNF331; SOX13; HOXC5; TAF5L; DAXX; GFI1; TCF21; SHOX2; ZNF266; SP140L; E4F1; UIMC1; TRIM24; NCOA4; ELF5; BCL11A; HLX; TOB1; TRIM22; ZNF239; TFAP2A; LHX3; ZNF426; STAT5A; ARL2BP; FOXJ2; ZNF589; SERTAD2; LMCD1; KLF1; IRX4; FOSB; PRDM10; HES1; LZTR1; GATAD2A; LYL1; WT1; CEBPG; AEBP1; TFAP2C; HIC2; TCEB2; HOXA1; KLF10; LIN28A; GATA1; ZBTB16; SOHLH2; CCNH; TGIF2; MLXIP; KLF13; GATA4; NCOA6; FOXI1; PRDM14; TRIM25; CDK9; HDAC9; HIRA; ID1; KDM5C; EGR2; CRYM; ELF1; PEG3; NANOG; UBE2I; FUBP1; TGIF1; CBFA2T3; KLF3; GRHL2; KLF6; ELF4; AFF1; SATB2; MECOM; RUVBL1; BTG1; MYCL; NFE2; NR4A2; IFI16; SCAND1; ZNF281; RNF6; ARID5B; PFDN5; PSMC3; CCNE1; MAFB; CEBPB; GATA2; MYBL2; ETS2; ATF5; JUND; MEIS1; MYBL1; PBX3; HOXB2; VPS72; MKL2; FOXC1
Down-regulation	165	USP22; PSIP1; RUVBL2; TLE1; DDX5; ZMYM2; HLTF; ZNF23; BCL3; TERF1; NRIP1; TBP; CRK; ARID1A; NUP62; TRIM28; HIVEP2; EYA1; BAZ2B; SIX2; BAZ1A; KDM5A; SAP18; NCOA2; PLAGL1; BBX; SUPT7L; BASP1; APEX1; GTF2IRD1; ZMYND8; CITED1; SMARCD3; MYT1L; PAXBP1; ELF3; ZNF33B; TCF7; TRIM29; INSM1; BRD8; VGLL4; HSF2; ZNF473; RBPJ; NR1I2; SMAD5; DRAP1; ZFHX4; EMX2; ZKSCAN1; ZNF146; PATZ1; KAT6A; PSPC1; HIVEP1; BPTF; NR2C1; BMI1; ZNF226; TLE4; HDAC6; SMAD7; ASXL1; RBPMS; NAB1; ZNF536; HMGN3; TOX; C1QBP; RBBP4; ZNF7; KAT7; ETV5; MED23; MYB; ZNF3; EZH2; SMAD4; ATF2; ZNF292; HDAC2; POU2AF1; MDM4; TSC22D1; IKBKAP; MTF2; TCF12; DPF2; ARID4B; PBXIP1; NHLH2; CAMTA1; CBX3; HOXA7; BCOR; FOXD1; PHF8; ZIC1; TAF1D; ZNF302; PCGF2; MAGED1; PCBD1; ZSCAN18; CBFB; ID3; JUN; TCERG1; BCLAF1; NFE2L1; ZBTB24; WWTR1; ZNF274; ASCL1; MTDH; HOXB7; CTR9; SATB1; BATF3; HLF; ZNF652; ID2; PITX2; NFAT5; RFX7; TSC22D2; MSX1; RUNX3; RNF111; ESRRG; CRY1; ZBED2; ZNF248; ZNF587; RYBP; NR1D2; HIPK3; AHR; POU4F1; HMG20A; MGA; TRRAP; ZNF721; PBX1; HMGB1; ZNF160; SALL1; SMARCA1; REPIN1; ZBTB38; BHLHE41; JARID2; TRIP6; PEX2; ZBTB18; SIX1; PUF60; KDM5D; ATF3; PDLIM1; HOXB6; ZNF12; SOX4; ZEB1