Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID65083	Proxymetacaine	GSE92742	NEU	Human	24h	10uM	EID0360

Response Information :

Types	Number	Response transcription factors
Up-regulation	117	BHLHE40; PHF1; CNOT6; DAXX; ZNF239; NAB2; RXRA; GTF2I; NFKB2; MED16; DNAJC1; SP140L; WNT4; ZNF276; E2F6; IRX5; RCOR1; THRA; SSBP3; GTF2F1; TEAD4; NPM1; MYCN; MBD2; ETV5; RING1; RERE; FOXJ3; EP300; CDK2; HOXC10; NR0B1; NFIC; ERBB2; AR; HOXA1; TXNIP; MED21; ERF; PITX1; PRDM1; PAX6; IRF6; SIAH2; ARNTL2; NOC2L; HLTF; SREBF2; ZSCAN31; NR2F1; TP63; DDX54; SLC2A4RG; VGLL1; SMARCD3; NR4A1; ERCC3; WT1; ITGB3BP; KAT2B; CBFA2T3; AES; TBX21; SALL1; CREM; NFYC; IRF5; CBX6; CITED2; TLE2; MNAT1; ZSCAN18; TGIF2; NFE2L2; TGFB1I1; MECOM; KLF6; TBL1X; IRF9; BRD2; ZNF274; ZNF512B; BRD4; PTTG1; NKX2-2; FOXL2; CDK9; SMAD6; JAK2; CTNNB1; ARID5B; TGIF1; FOSL2; OSR2; TAL1; NR2F2; HMG20B; RFX5; FOXO3; ERBB4; FOXC1; BHLHE41; ESR1; ID1; PFDN5; TBX2; CBX7; ELF1; KLF2; CEBPD; NR4A2; SIX1; ZBTB38; HHEX; HOXA5; TGFB1; MTA1
Down-regulation	136	ZMYM2; ZNF131; HIF1A; ZNF302; MAF; HOXD1; DMTF1; NPAT; NUP62; ZNF468; ZBTB20; NR1I2; PROX1; BPTF; INSM1; ZNF652; UBE3A; TLE1; RBPJ; TMF1; MED14; HAND1; GFI1; RYBP; BCL3; CNOT2; TBX3; NCOR2; TAF1D; FOXF1; PMS1; ZNF224; MDM2; ZNF107; PHOX2B; BTAF1; TEAD1; NFAT5; ZMYND8; DDX17; PLAG1; NFIL3; NR1H3; UBE2L3; ZNF232; BAZ1A; PAXBP1; MED13; MTF2; ZNF573; SPI1; FOXO1; ZNF611; SAP18; SMARCB1; KMT2B; LMCD1; KLF9; TULP4; SAP30; ZNF83; WWP1; ZNF292; ISL1; PITX2; NR2C1; NFE2L1; ZNF264; ZNF146; ZKSCAN1; NR2F6; ELF5; ZNF165; MLXIP; SATB1; ZNF22; GTF3A; TCF7L2; ZNF721; FUBP1; ZBTB1; ZNF248; HTATIP2; TOX3; MSX1; ERG; SOX10; KLF7; ID3; ASCL1; E2F8; E2F3; BIRC2; HOXB7; TCF7; ZNF44; NFATC4; MTDH; SREBF1; CHD7; PEX2; HDAC6; FOXA2; ZBTB18; LEF1; NR1D2; ZNF195; ZNF160; CERS6; AEBP1; ZNF587; HMBOX1; ZFPM2; MED1; ST18; CSDE1; FOSB; NFATC3; NCOA3; WWTR1; RUNX1; ZNF589; PHF20; PBX3; NKX3-1; BTG1; MEOX2; MYC; ABL1; VPS72; HOXB5; PDLIM1; KDM5D; ATF3; HOXB6; FOXG1