Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID64896	Jak3-inhibitor-v	GSE92742	NEU	Human	24h	10uM	EID0359

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	GATA6; ADRB2; PPARG; PPARD; ETV1; FOXF2; IKZF1; TFAM; POLR3C; GATA3; VPS72; HOXC11; ZNF124; SPDEF; NFYA; ZNF512B; ELF4; JUP; HOXB2; MED14; SMARCD2; CDIP1; HOXD11; EED; PROX1; TRIM25; TXNIP; HLX; MEIS1; FOXL2; NR0B2; KLF7; IRF9; NAB1; PAX8; TAF9B; BCL3; NEUROD6; LHX3; PBXIP1; RBL2; MYC; TCFL5; BACH1; NFATC4; VDR; IFI16; CSDE1; RBFOX2; STAT6; ACTL6A; NFAT5; FOSL1; ZNF131; PPP1R13L; ERBB4; MLXIPL; RFXANK; KAT2A; KLF9; RUNX1; HOXB6; CBX6; ZNF665; CEBPD; NFE2L2; AR; KLF11; ATF3; FOXO1; SOX17; MLXIP; AHR; IRF6; KLF10; SLC2A4RG; ETS1; CREB1; BCL6; HOXB5; MED13; WT1; FOXC1; HOXB7; ZBED2; SMARCD3; SERTAD2; ZNF117; ELK4; AIP; ZNF264; LOXL2; HOXD1; MKL2; RB1; RELB; BCL11B; PDLIM1; RBPJ; CD3D; EYA2; MITF; KDM5B; HHEX; TRIM29; ZBTB38; CEBPB; SOX9; KLF4; PEG3; TBL1X; MAFB; ESR1; TCEA2
Down-regulation	157	ZNF281; INSR; CENPB; CTBP2; ZBTB18; ZBTB24; ZNF423; HMGA1; NFIB; NKX2-1; EGR3; RCOR1; SOX2; TRIM28; SOX12; ZMYM2; ZNF516; NPAT; NR2C1; TBL1XR1; USF2; AGO2; ZBTB1; TCEA1; TLE1; BRCA2; USP22; TBPL1; BHLHE41; PSPC1; TRIM24; CHD7; PTTG1; MYB; ZNF146; PPARGC1A; ID3; RCOR3; ISL1; DPF2; ZNF443; DACH1; KAT2B; MGA; EYA1; RXRG; SFPQ; BAZ2B; PSIP1; TSC22D3; CBX5; ING1; SMARCC1; ZSCAN16; PCGF2; SUZ12; ZNF268; TBP; EDF1; ZBTB11; IRF4; POU3F2; ETV5; PATZ1; SMAD7; ZNF184; TBX3; ADNP2; ZNF14; SMAD4; ZNF302; BASP1; PSMC3IP; CCNC; TGIF1; BRPF1; ORC2; JARID2; SALL2; MYCBP; ATF5; SMAD6; SAP18; RBM39; MAGED1; SMARCA2; SALL1; ATF1; RUVBL2; REPIN1; RNF138; BRD3; DNAJC1; HSBP1; HNRNPD; TAF10; PLAGL1; LIN28A; TCF4; TAL1; SAFB2; NFKBIB; IRF1; CREBZF; SAP30; ASCL1; ID1; DAXX; TCF12; HSF2; ZNF536; ZNF84; ARID5B; DNMT3B; SMAD2; CAMTA1; ENO1; HMGN3; MAFG; POU4F1; YBX1; CRYM; MAZ; RREB1; NR3C2; HDAC1; ZNF532; HMGB3; HMGB1; SATB1; ABL1; FLNA; POU2AF1; ZIC1; SMARCA5; ZNF551; SMARCE1; ITGB3BP; AFF1; ZEB2; JUND; ZFHX4; BIRC2; ZNF107; RORA; RBBP4; RFX5; SIX1; BMI1; XBP1; PBX1; KLF2; FOXG1; TFAP2C; MNAT1; DMTF1; ZNF586