Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID64727	Phenformin	GSE92742	NEU	Human	24h	10uM	EID0359

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	MEF2C; ADRB2; KDM5A; CREG1; GATA6; GATA3; IRX5; CITED2; GATA2; RAN; ZNF160; ZNF611; ZNF721; TRAK1; NFKBIB; RFX2; IL16; EP400; MAF; HDAC11; NRBF2; SCMH1; BARX2; BCOR; CHAF1B; BATF; ZNF292; GFI1; TRIM24; LMCD1; EP300; HOXA7; ARNTL2; ELF3; NCOA4; WWP1; CHD7; POU2AF1; CBX3; ZNF44; HEY1; DLX2; ZBTB1; SMAD6; EWSR1; PAX5; TOX; HMGB3; FOXJ3; PIAS2; EDF1; BAZ1A; SOX2; YWHAB; TBX2; ZNF562; TAF12; EGR2; CARHSP1; ZNF131; HNRNPD; FOXG1; LIN28A; ZNF24; DNMT3B; ELF4; ID1; ZNF665; RBBP4; ANKRD1; HOXC4; WWTR1; RBBP5; FOXC1; MLXIP; ENO1; YBX1; ZBTB20; CAMTA1; INSR; ARRB1; CREB5; TAF1D; MAFG; HOXA5; TBL1XR1; HIC2; SMARCA1; KLF6; SMARCA5; HDAC1; PITX2; FOXD1; ATF5; CDK7; ZNF117; KDM5D; PAX6; HMGB2; NR2F1; KLF4; MNDA; SOX11; LITAF; KAT6B; KLF10; TCEB2; MAFB
Down-regulation	195	THAP11; TAF6; ELK3; CTBP2; CDX2; TSC22D1; ST18; ZNF12; SSX1; BRD2; TGFB1; NR1I3; HOXB2; HMGA1; TGIF2; SALL2; TERF2; PBRM1; AEBP1; TCF25; ARID5A; SIX6; RING1; HMGB1; RELA; MED13; MYBL2; JUNB; DNAJC2; TGFB1I1; ESR1; ZNF354A; MEOX1; POLR3C; ERF; HBP1; ZNF146; JAK2; TGS1; PCGF1; ZKSCAN5; MYB; ZNF423; KDM4C; HIVEP1; MXI1; ETV5; HDAC7; CCNC; ZBTB16; NRIP1; SP100; IRF2; COPS2; ZEB1; SIN3B; SIM2; ARNTL; TRIM28; JUN; KLF9; CRY1; CLOCK; EHF; SND1; ZFP36L1; ZNF552; ZNF467; RBPMS; ZNF148; NPM1; ETV4; NFKB1; ZNF331; ZNF33B; ING3; SUB1; BRD8; ILF2; BCL11B; ZNF444; TRIP6; PHF1; URI1; DPF2; SP2; OVOL2; HIPK3; CBX6; HLTF; SFMBT1; PATZ1; E2F4; DEK; DAXX; TCEA1; ZKSCAN1; CNOT3; PBX3; CERS6; KAT7; DRAP1; RNF141; SMARCC2; ATF6; NKX3-1; SP3; SOX17; PBXIP1; CDK8; RYBP; PAX8; UBP1; ZNF273; PPP1R13L; HEY2; ZNF415; SIX2; NFIL3; SPDEF; HOXB6; EHMT2; ZNF239; STAT4; OLIG2; IRF9; ARID1A; RBM39; IRF7; ZNF580; MYC; ZNF589; STAT1; CHD9; NR3C2; ZBTB18; BRD4; RFXANK; MED4; CNOT6; PGR; RARA; PSPC1; TCF4; RNF4; KAT2B; CEBPB; RNF6; HDAC4; ITGB3BP; ZNF14; DMTF1; NFIB; NR0B1; CUX2; HOXC10; MYCL; SFPQ; ZNF302; BCL6; FOSB; RFX5; RUNX3; HDAC9; MKL2; WT1; OSR2; IFI16; FOXO3; LEF1; HIVEP2; PRMT2; AR; GATAD2A; CRYM; ZFP36L2; RBFOX2; CREB1; PRKDC; ZSCAN18; TXNIP; ERG; RHOA; PBX1; MSX1; REPIN1; AES; ZBED2; NR1H2; IRF8; FHL2; NFKB2; DACH1; RB1; NKX2-2