Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID64648	Pirfenidone	GSE92742	NEU	Human	24h	10uM	EID0358

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	SMAD2; RB1; HAND1; SMARCA5; RUNX1; BIRC2; CERS6; TLE1; REST; TSC22D2; NPAS2; KDM2A; CREG1; PHOX2B; CTR9; DLX5; TBX2; KDM5D; TRRAP; SUV39H1; BRPF1; MSX1; SIM2; HMGN3; NUP62; RBPJ; HLTF; KMT2A; ZNF24; RBBP5; EMX2; ZNF177; DDIT3; DPF2; TAL1; NFYC; KDM5A; BTAF1; TAF1D; PEG3; MTF1; ZNF721; BATF3; CDK7; RBM14; BHLHE41; CHD9; FLNA; TBL1XR1; RLF; DRAP1; ZNF23; ERBB2; BRD8; ZNF248; PATZ1; ZMYM2; ZNF146; ECD; ZNF160; SMARCC1; KDM5B; ZNF273; TCF4; PCGF2; SUZ12; PTTG1; ZNF611; SAP30; TCEB2; CARM1; MTDH; NFAT5; FHL2; WWTR1; ZNF426; MED1; ZNF532; BCL11A; EDF1; MEIS1; DNMT3B; KAT6A; DLX2; SIX1; BBX; SMARCD3; TCF12; MBD2; MITF; TBL1X; TRIM29; TBP; BASP1; MYCN; MAF; TCERG1; MECOM; ZKSCAN1; ZNF589; PIR; ELF5; PAX6; TRIP6; MYB; ZNF652; ABL1; PLAGL1; FOXF1; EZH2; SCAND1; GATA2; NCOA4; TBX3; VGLL4; LEF1; NFIL3; CITED2; POU4F1; MTF2; TLE4; ZMIZ1; RBPMS; HHEX; PBX1
Down-regulation	86	THAP11; SPDEF; BNC1; CTBP2; ACTL6A; PNRC1; KLF10; PSMC3; RORA; ARID5B; HOXA5; CLOCK; ZFP36L2; JUP; RHOA; RAD21; ZNF239; MSC; OVOL2; KLF3; PRMT2; NPM1; CNBP; CNOT6; SRCAP; BCL3; RARB; TGFB1; BNC2; ATN1; ERBB4; ELF4; RNF6; SOX9; ID1; MYBL1; FOXG1; TGIF2; KDM4C; FOXJ2; ZNF557; NR4A2; KLF4; CEBPD; JUND; GATA6; STAT1; FOSL2; ZNF331; NR3C2; NR4A1; CREBL2; LITAF; TP63; SSBP2; TXNIP; KDM5C; ZNF22; KLF9; KLF7; KLF2; ARL2BP; ZFP36L1; HMGB1; LMCD1; TDP2; PCGF1; PEX2; HDAC9; CRYM; MEOX2; ZBTB16; ARNTL2; ERG; FOXA2; RXRA; ATF5; PPARD; BHLHE40; KLF13; FOSB; ZHX2; IFI16; IRF6; TRPS1; NR3C1