Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID64583	Proxymetacaine	GSE92742	NEU	Human	24h	10uM	EID0358

Response Information :

Types	Number	Response transcription factors
Up-regulation	117	STAT3; ETV1; RRN3; REL; MYCL; IFI16; ZNF112; RB1; MED15; CREB1; KLF6; SP140L; ZNF267; NR0B1; HLF; PRRX1; TFEB; TULP4; TFCP2; MAFB; PURA; MAFF; FOXF2; ZNF140; ZNF45; CREB5; MED7; NKX3-1; BAZ2B; BPTF; TTF2; SMAD1; EYA1; CRK; TDP2; ING3; TBX3; TAF9; CNOT6; CREB3L1; SP110; HDAC9; TRIM32; RYBP; NCOR2; ASCL1; HDAC4; SIM2; ZNF85; ZNF217; CBFB; PPARGC1A; TAF7; ZNF423; DACH1; ZBTB20; ETS1; YEATS4; ZNF268; EYA2; RNF10; ZBTB38; HIVEP2; ZNF84; IRF2; ZFPM2; KLF5; NFE2; ZNF652; TOPORS; KAT7; WWC1; NANOG; TBX2; GCFC2; TLE2; IRF8; CREBL2; FOSL2; MED13; ELK3; ZHX2; ID4; ZNF264; POU2AF1; AEBP1; ECD; TRIM22; ZNF148; IRF1; ZNF430; ESR1; HDAC6; ABL1; MNDA; PCBD1; FOXJ3; HOXB2; ZFP36L1; FOXN3; ZMYND8; MAGED1; MSX1; RXRA; INSM1; MXI1; SMARCA2; SOX9; KLF2; BASP1; SUB1; ZMIZ1; VGLL4; PBX1; SNAI2; FOXF1; MTF2
Down-regulation	95	PIAS2; ZNF444; E2F5; HINFP; CXXC1; RUVBL2; ZNF211; MED20; BACH2; RUVBL1; SMARCD1; MED27; HSBP1; RBBP8; ZNF302; SMARCA5; KAT8; WWTR1; BANP; ZNF768; ZNF593; DRAP1; DNAJC2; YAF2; MMS19; PSMC3; ZNF219; RHOA; VEZF1; HDAC1; TFEC; PHF1; HDGF; TAF12; GTF3A; ZBTB1; ELF4; TCF4; KMT2A; MYC; DAXX; TRRAP; ATF5; NAB1; ELF2; VPS72; CDK7; SMARCA1; RERE; LITAF; SAP30; HMGB3; MED17; BATF; CEBPG; AIP; MEN1; TRIM28; TCFL5; PUF60; CEBPD; PEX2; SPIB; KLF7; ZIC1; ZBTB16; NFAT5; SATB1; MXD4; TCF7L1; ZNF580; FOXD1; NFE2L1; MEOX2; HOXA5; NFATC1; ZFP36L2; SIX2; WT1; EZH2; PCGF2; BTG1; REPIN1; ZNF22; MKL2; ENO1; HHEX; TRPS1; EN1; NKX2-1; ID2; IRF6; TXNIP; SMAD3; GATA2