Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID64468	Pyrazolanthrone	GSE92742	NEU	Human	24h	10uM	EID0358

Response Information :

Types	Number	Response transcription factors
Up-regulation	165	HOXC6; RRN3; STAT6; EGR2; JUNB; TGFB1; CBX7; HDAC9; FHL2; RERE; LITAF; GRHL2; ZNF444; ELF3; MEF2A; TRIM22; TAF5L; HOXC4; CNOT3; CAMTA2; BHLHE41; TAF1; TOB1; TFCP2; TGFB1I1; TAF4B; SP1; HOXA4; TMF1; TFEB; PPP1R13L; KLF10; PAX8; PTRF; EGR4; HOXB6; NFKBIB; THAP11; MED15; BNC1; EGR1; NFE2L2; VGLL1; ACTL6A; BAZ2A; HOXC10; SMAD7; HES1; HIPK3; MITF; NAB2; NR4A1; TFEC; FOXC1; HOXB2; ZNF12; PNRC1; OVOL2; PGR; IRF1; YEATS4; EGR3; CRYM; ZNF394; NFKB2; POU2AF1; STAT2; RBL2; HOXB5; SSX1; KAT2A; SMARCA2; NR1D2; IRF2; SNAI2; MED14; HOXA1; MAFF; EHF; UBE2B; ATF3; TGS1; FOXK2; IRF3; HLF; IFI16; NR0B1; KLF9; VDR; TTF2; IRF5; CERS6; RING1; TFCP2L1; NFE2L3; FOSB; FOXE1; AHR; TP63; MYCL; MYC; ZNF557; IRF9; TFAP2C; ADRB2; JUP; ETV5; NFE2; CREBL2; BAZ1A; SSBP2; DBP; PCBD1; IRF7; ETV6; TFAM; ELF5; EYA2; IRF8; KLF4; ELF1; UBP1; RBPMS; FOXF2; IRF6; TRIP4; ZKSCAN1; ESR1; IRF4; TOPORS; REL; TAL1; SAP18; SUB1; NFATC4; JAK2; HOXB7; POLR2A; CREB3L2; ARID5B; THAP10; ZBED2; SOX9; ZNF264; TBX2; NR1H2; PRRX1; CALR; MKL2; ZNF652; ING3; CBX6; IL16; SPIB; SP100; HOXA5; JUN; SMAD3; ZBTB38; OSR2; NCOA2; PEG3; ZBTB16; STAT1; EMX2
Down-regulation	227	SOX11; BACH2; KAT6B; MEIS2; E2F5; ZNF302; ZNF532; HDGF; PUF60; ZNF281; WHSC1; SMARCA5; CHD7; MNT; ZNF93; ID1; ATF4; FOXG1; CEBPZ; SOX2; UBE2I; ZFHX4; BRD3; HOXD10; CENPF; ZXDC; UBE2L3; USP21; KMT2A; DACH1; PRPF6; ZNF257; PATZ1; RAN; RNF4; LZTS1; TBL1X; ZNF24; GTF2IRD1; EYA1; WIZ; ZNF573; SMARCA4; ZNF423; BIRC2; RBBP4; PMF1; PIAS2; ATF7IP; DRAP1; CITED1; DEAF1; TCF4; ZNF334; TCEB2; ZNF562; CAMTA1; HNRNPD; KLF7; NFKBIA; ZNF248; TOX; LDB1; ZEB1; MAGED1; ENY2; EDF1; ZKSCAN7; ARID3B; PITX2; KAT5; SMARCE1; ZNF711; E2F6; ISL1; PARP1; ZNF358; ZNF177; XRCC6; ZSCAN12; RBM39; KLF3; ZNF506; ZNF253; SUZ12; KAT6A; SUV39H1; YBX1; TAF1A; CCNE1; PSMC3; HSBP1; SIX3; CLOCK; TCF25; APEX1; SCAND1; NELFB; CHD8; SOX4; ZSCAN9; CSDE1; ASXL1; POU2F1; NFIC; VEZF1; BASP1; NFIX; CUX2; ZNF443; ZNF189; ERBB2; SOX12; SMAD1; NUP62; ENO1; HMGB1; RBPJ; TOX3; RBM14; ZNF43; SMARCC1; DNMT3B; GFI1; ILF2; HMGB3; HDAC1; ZNF219; PBX3; MKL1; CARM1; ZNF783; CENPB; CRY1; RFC1; INSM1; KLF11; NCOR1; YWHAB; KDM5D; HMGB2; STAT4; URI1; BANP; CREM; NFKB1; ADNP2; SREBF1; CUX1; RHOA; NONO; ATF5; HEY1; ZFP64; DMTF1; SPEN; PFDN5; SALL2; FOXJ3; L3MBTL1; PTTG1; DDX17; HMGXB4; KDM2A; SMAD6; TAF10; PHF20; USF2; ZNF292; SATB1; HMGA1; ZFPM2; TCF12; ZNF3; CTBP1; CDYL; HMBOX1; TULP4; MED7; CCNA2; RNF138; CARHSP1; HIRA; MED16; HOXD3; POU3F2; GTF3A; BRD4; NEDD8; SALL1; TFDP2; RSF1; BAZ2B; KDM5B; NCOA6; RORA; MYCN; BCLAF1; AFF1; SMARCA1; BTG1; LPIN2; WT1; BCL10; HIC2; GATAD2A; PCGF2; TCF7L1; MEIS1; TCFL5; TCERG1; XBP1; TGIF1; EP300; TSC22D1; ZNF44; NR4A2; TRIM28; PQBP1; POU4F1; MECOM; HMGN3; NCOA4; ZHX2; JARID2; IRX5; ID4