Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID64412	Alprenolol	GSE92742	NEU	Human	24h	10uM	EID0358

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	NEUROD1; CREB1; ZNF239; KLF6; ESR1; SUPT7L; ZNF331; ZNF473; CREM; ZNF34; TOB1; ZNF274; NFKBIA; ZNF350; ZNF134; KLF10; ZNF432; NFX1; SMAD7; CUX2; ZNF394; ZNF337; BHLHE41; CERS6; CRK; ZNF512B; CREB3; HDAC6; EMX2; ZNF32; SRF; TFEC; SALL1; TAF5L; PRMT2; REL; MAFB; SOX17; ZNF551; MYB; MYCL; JUP; JUN; ZNF140; ATF1; KLF4; NKX3-1; IRF7; ZNF589; FOXN3; JAK2; NR0B1; FLI1; ZBTB43; SSX1; PCBD1; TLE2; MED6; MED1; ERG; ZKSCAN1; SAP18; TAL1; NR4A3; TBX2; HOXB13; IRF9; ZNF107; AFF1; TOPORS; EYA1; ZIC1; CBX7; PAX6; ZNF124; TEAD4; IFI16; ZNF136; MAFF; ZNF426; ZBTB1; TRIP6; MNDA; TFAM; HHEX; DEK; ETS1; ZFPM2; IRF8; IRF1; SAP30; NFKB2; ZBTB16; FOSL2; ID2; MXI1; ZNF22; ZNF264; SMARCA2; TCERG1; TCF12; ZNF652; TXNIP; INSM1; ZBTB38; TRIM22; EHF; HOXB6; IRF6; SSBP2; KLF9; PBX1
Down-regulation	108	USP22; MNT; ZXDC; SMARCA5; LDB1; SREBF1; MDFI; HDAC1; KMT2B; MED4; BRD3; SPEN; E2F5; TSC22D1; HDAC7; BARX1; POU5F1B; CITED1; TAF1D; FOXO4; PIAS2; TCEB2; RFC1; PEX2; SREBF2; SPI1; NR2F1; CHD4; BIRC2; ETV4; HSBP1; TCF25; IRX4; NRBF2; CBX6; BACH2; NFATC1; ZFHX4; PIAS3; FOXO1; RNF4; SUZ12; DLX5; MYRF; HMGA1; DMTF1; GTF3A; TULP4; KDM2A; SMAD6; TCF7L2; DLX2; HOXA7; ARNTL; RUNX1; RHOA; DNMT3B; HEY2; BRD8; POU2AF1; SMARCE1; KMT2A; ZMYND8; BRD4; SUPT6H; ATF5; CCNE1; AATF; CARM1; RBBP4; RNF6; FUBP1; HOXA5; TBPL1; NANOG; CREB3L1; NR1D2; CCNA2; ZNF131; ISL1; JARID2; PUF60; FOXD1; ZNF711; YAP1; TAF10; CSDE1; CBX3; RBBP8; CAMTA1; DRAP1; MKL2; VPS72; KDM5B; HLTF; FOXF1; TOX3; NCOA2; TCFL5; ID4; LOXL2; TLE4; TCF21; MAGED1; HTATIP2; SMAD3; GATA2; TBL1X