Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID64051	Brimonidine	GSE92742	ASC	Human	24h	10uM	EID0356

Response Information :

Types	Number	Response transcription factors
Up-regulation	327	TCFL5; SUV39H1; FOSB; FOXJ3; NFATC1; ZNF131; SMARCC1; PURA; ADNP; KDM5B; SERTAD2; EP400; TXNIP; PAX5; ELF5; ASCL1; PQBP1; NR3C1; RELA; BCOR; SIX3; NFYC; POU4F1; RUNX1; POU2AF1; IRX5; SMAD2; ZNF778; RUNX3; DEAF1; IRF2; L3MBTL1; URI1; HCFC1; FOXA1; ZNF711; PPP1R13L; ZBTB48; RBM14; BCL11B; NR4A1; CHD9; BAZ1A; ZBTB1; NAB1; SNAI1; SIM2; MTF1; TCF4; FOXE1; PHF20; CBFA2T2; MZF1; CHD7; RBL1; PRKDC; SOX21; SOX10; RERE; CBFA2T3; BPTF; ZNF692; E2F5; HDAC6; ETS2; DLX4; KLF10; BATF; OLIG2; BTG1; TULP4; PHIP; ANKRD1; CREB3L1; SMARCA1; TOX3; HEY1; TSC22D2; ZNF783; NKX2-1; HNF1B; GLI3; HOXB1; GTF2I; YY1; NSD1; NOCT; MAGED1; BLM; ID4; GRHL2; MED12; SMARCA5; MED13; TP73; HOXA5; PAX8; BHLHE41; GATA2; KDM4A; BAZ1B; BMI1; HOXC10; MKL2; SOX13; MNT; SMARCD2; YWHAB; NCOR1; LEF1; RARB; ZNF556; HLF; CNOT1; CIZ1; TCF20; TAF4; NCOA6; DPF2; IFI16; FEV; POU3F1; HDAC1; NKX3-1; NFX1; IRF4; ZNF107; BACH2; MAFG; NFKBIB; REL; IRF9; HMGN3; IRF3; PIR; TCF7; DDX17; GTF2IRD1; HDAC4; USF2; FOSL1; IFNB1; PREB; ELF3; ZNF629; HLTF; PBRM1; TCF12; TLX3; HIVEP3; PIAS3; PHF8; MYRF; TFCP2; ZKSCAN1; ZNF146; TOB1; ZMYND11; IL16; ZNF764; ZMYND8; NR4A2; ARID1A; ZSCAN18; PCBD1; CBFB; ZBTB24; ZNF160; CDYL; NR4A3; EYA1; FUBP1; MNX1; ZNF331; EZH2; RARG; DLX5; ZMIZ1; TCERG1; RBBP5; PUF60; ING1; TFAP4; BRD7; EYA2; SIX2; PLAGL2; WWC1; MED24; PBX3; ZHX2; CBX2; PIAS2; SOX11; AATF; FOXD1; ZNF652; JUNB; CREBZF; ZBTB44; MXD1; PRRX1; NFKBIA; ZNF721; DRAP1; ZNF267; RBL2; HOXA1; NR0B1; TERF2; SREBF2; NR1D2; HOXC6; HDAC2; SP2; ZNF274; AEBP1; RSF1; ID1; ID2; BASP1; DBP; EZH1; ZBTB39; NPAT; BBX; TRIM24; IRF1; STAT3; IRF7; EED; KAT5; CHD8; SMAD4; ZNF771; MDM2; ZNF202; RBBP8; MEN1; LZTS1; THAP11; KAT6A; WDR77; BCL6; MYB; RHOA; YBX1; ZNF430; MYBL2; SMARCC2; MBD2; NFIC; ZBTB38; NCOA1; HES1; BRCA1; MYC; FOXO1; SFPQ; TRIM22; TGFB1; EGR3; ZFY; CD3D; CNOT6; SMAD6; NFE2L2; CBX5; GLI2; ZNF165; HSBP1; KDM5D; ERBB2; TP53; ZFHX3; PMS1; PATZ1; SATB2; PAWR; NUP62; TFCP2L1; CTR9; CREB3L2; NHLH2; BHLHE40; CENPF; STAT1; ZNF124; TRRAP; ING2; BAZ2B; TBX2; CHD4; MYCL; TAF7; SIX1; ERG; ZNF24; KLF4; SHOX2; EHF; HOXB2; CERS6; VGLL4; EGR1; SSBP3; MXI1; CTBP2; FOXN3; TFDP1; ETS1; SIAH2; ZBTB18; SOX9; TCEA2; HMG20B; TFDP2; IKZF1; HTATIP2; SCAND1; NR2F1; TFAP2C; BIRC2; CRK; EGR2; ID3; ATF5
Down-regulation	257	CDK7; DAXX; ZNF83; TSC22D3; DNMT1; APEX1; ETV4; TULP3; CBX3; CEBPD; PPARG; MED15; ENY2; ZNF32; ZNF189; TSHZ2; TRIM29; LOXL2; MLXIPL; HIRA; MEIS1; ZFPM2; ESRRG; TGFB1I1; ABT1; ZNF646; MEOX1; TONSL; FHL2; SP140L; ERBB4; TAF12; ZNF76; YEATS4; ING4; JUP; ZNF468; SIX6; HMGA1; ZFX; RNF4; ZNF205; NR5A2; PRDM4; RYBP; ZNF177; RREB1; YBX3; NEUROG1; XRCC6; TDP2; NKRF; TOX4; UBE3A; ZSCAN2; MEOX2; NR1H2; TCF15; TRAF6; NELFB; ZNF816; ADNP2; LIN28A; ZFHX4; ESR1; ZNF410; RFC1; TLE4; SUB1; RXRG; PNRC1; POLR3C; ZNF358; HMX1; IRX4; WWP1; ZNF281; MED21; PTTG1; CREG1; ZNF302; ATF4; NANOG; SP110; TRIM27; CERS4; ZNF12; ZNF562; ARID5B; ZNF415; ARL2BP; ZNF345; ZNF3; PEG3; ZNF44; HIVEP1; ZNF239; ZNF184; SMAD1; BLZF1; FHL5; MED23; E2F3; RNF10; SP100; PTRF; INSR; FOXM1; HDAC7; ZBTB43; CDIP1; TAL1; ZNF500; ZNF384; MECOM; ZNF219; CAPN15; NRIP1; ATF2; CRY1; E4F1; ST18; TWIST1; EMX2; THRA; RBPMS; SIX5; MNDA; ZNF75D; DACH1; CDX2; ZNF573; TLE1; IRF6; ARID5A; ARNTL; TCEB2; PBX1; REXO4; CNBP; KLF1; HOXA3; RNF6; SAP18; THAP10; MMS19; KLF6; MAF; FOXF1; ZBTB16; ZNF350; TRIP6; SUPT4H1; NFE2; ZKSCAN5; TMF1; KMT2B; NR3C2; TEAD4; HOXA7; TAF6; ZNF467; MTA1; ZNF33B; HINFP; TAF9B; NR1H4; EN1; KLF11; ZNF8; ZNF224; ZNF140; CTBP1; HOXB7; CALR; HLX; ZSCAN32; ELF4; SOX17; SRCAP; TCF21; CITED2; FOXJ2; NR2F2; FLNA; ZNF45; PA2G4; KLF13; JARID2; ZNF211; TRPS1; CARM1; TEAD3; SETDB1; PPRC1; ZFP36L2; MAX; KLF2; TBX3; SUMO1; PMF1; RBPJ; PCGF3; GATAD2A; MXD3; ZNF264; ZNF136; ZNF593; NFKB1; SMARCD3; COPS2; DDIT3; POU5F1B; ZNF200; ZEB1; GTF3A; BCL3; MEIS2; AGO2; AR; BRD4; PIAS1; TRIM16; KDM5A; PAX6; ATF1; ARNTL2; OSR2; PLAGL1; PITX2; ARID4B; PSIP1; HCFC2; KLF7; ZNF266; NFIB; NFATC4; BRD2; NPM1; MXD4; ZNF22; HIC2; ELF1; GATA6; FOSL2; RAD21; KAT6B; SSBP2; ABL1; ZBTB20; SALL2; FOXG1; HMGB3; FOS; LITAF; MSX1; SATB1