Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID64019	Proadifen	GSE92742	ASC	Human	24h	10uM	EID0356

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	EED; GATA2; FOXO1; TBX3; TCF7L2; HOXB6; ZFP36L2; PATZ1; EN1; PKNOX2; XRCC6; HDAC6; BTG1; PRRX1; HMGB2; ATF4; FHL5; RXRA; HOXC4; HOXC6; MEF2C; TCEA1; SF1; HEY2; CENPB; RNF141; SIX6; TCF4; HHEX; TAF10; NKX2-2; TFEC; CBX7; ZNF384; ARID1A; ATN1; FUBP1; SPEN; GTF2F1; SRF; TAL1; MAFB; SOX13; MEOX1; IRF3; ID3; AEBP1; NR1H3; HOXA5; HLX; HOXB7; IRF8; SAFB2; EDF1; SLC2A4RG; ZBTB16; CTBP1; NR4A2; KMT2A; HLF; PCGF2; ERBB2; ZBED2; SNAI2; CREB3L2; ZKSCAN1; MSX1; CSDE1; LEF1; ZZZ3; ARNTL2; MEOX2; IRF2; GATA3; ZBED1; PEG3; HOXB2; ATF3; ELF1; REPIN1; PBX3; ZNF264; JUND; ARID4B; EGR3; FOXC1; NR0B1; SAP30; PPARGC1A; CUX2; ERG; ZHX2; CREBL2; PPARG; ING2; INSR; CALR; CTNNB1; SMAD3; NR2F1; KLF2; ZMYM2; HOXC10; NR1H2; SATB1; HEY1; IKBKAP; SMAD1; MXI1; ZNF589; PITX1; NFIL3; ATF5
Down-regulation	93	FOXJ3; ELF3; ZNF587; ZMIZ2; C1D; ZSCAN9; DNAJC2; ZBTB38; NRBF2; ELF2; BACH1; ZNF586; NR1D2; TBL1X; PPARD; NFE2L3; PAX5; HSF2; PMS1; CRYM; LDB1; CARHSP1; MITF; MED23; RBPMS; TOPORS; E2F5; RUNX3; ATF2; TTF2; PHF20; TULP4; BAZ2B; ZNF593; ABL1; MECOM; ZNF468; ZNF134; NFIC; PSMC3IP; VDR; PARP1; ZNF544; ELF5; BNC2; NFE2L2; ID2; SP3; TFCP2L1; SMARCA2; JUP; MAGED1; MEIS1; FOXG1; CREB3L1; AHR; KAT6B; CITED1; ZNF12; SSBP2; GTF2IRD1; MKL2; FOS; POU2AF1; KDM5D; TXNIP; TCERG1; JUN; RBPJ; BHLHE40; TFDP2; BASP1; DACH1; GABPB1; PLAGL1; STAT1; TCF12; TP53; TSC22D1; TOB1; TRIM22; TFDP1; KDM5A; ID1; WT1; ECD; DMTF1; HMGN3; NFIB; MYBL1; ETV1; ZFP36L1; E2F2