Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63999	Alrestatin	GSE92742	ASC	Human	24h	10uM	EID0356

Response Information :

Types	Number	Response transcription factors
Up-regulation	172	MTF2; TCF21; ID4; KLF5; FUBP1; GATA2; ARID3B; PHF1; SMARCC1; TBX2; ZNF331; FOXH1; ZNF329; SOX11; TDP2; FOXF1; TOB1; ZNF586; PAX1; SUPT3H; MNAT1; ZFPM2; ZEB1; NANOG; CDC5L; PRDM12; TAF5; ZBED2; BRD7; PIR; ZNF180; CDK8; CBFA2T2; ZXDC; ZNF93; ZNF354A; NFYB; MED13; ZNF140; BPTF; TWIST1; PHIP; TERF1; PRRX1; NCOA2; TRIM29; TRIM24; PEX14; MED14; PRDM14; STAT4; BCOR; PQBP1; ZFX; ZNF721; AEBP1; ZNF268; TCEB2; ZNF611; DACH1; PBX2; DLX5; TCF4; IRF2; TAF5L; HIPK1; SMAD4; MNDA; VEZF1; ERBB4; NR2F1; ETS1; MYBL1; HOXB1; NFE2L3; BCL11A; PSMC3; SSX1; ZNF652; ZIC3; PBX1; ZNF423; CUX1; POU2AF1; TP63; POU4F1; DAXX; RBFOX2; TCF3; MEIS2; E4F1; DDX5; HBP1; NR0B1; ZNF623; CTBP2; MKL2; CREM; SUPT4H1; ZNF195; COPS5; FOXE1; ZNF589; INSM1; CNOT6; CDK2; HIC2; NR2C1; ZNF606; E2F5; UBE3A; NKX2-1; ETV1; CBFA2T3; ZHX2; ZNF562; ZNF512B; ZNF217; LYL1; TFDP1; NR4A3; ID1; RAD21; PBX3; FOXG1; SMARCC2; TFAP2A; E2F3; AHR; NFE2L2; TGIF2; SFPQ; TRPS1; ZNF160; IRF7; HMGB3; ZNF232; TCEA2; MAFB; BRD2; FOXF2; HOXD1; EPAS1; HIRA; ARNT2; ING2; KLF13; MECOM; SALL2; CREBL2; MYCL; WT1; CD3D; TFDP2; RBBP8; PPARG; CCNH; TOX; ARID5B; ZSCAN18; PEG3; HMGN3; HMGB1; ZBTB38; THAP11; LITAF; LEF1; SHOX2; ZBTB20; CITED2; CREB1; BASP1
Down-regulation	162	ZNF146; NELFB; HOXB6; PSMD9; FOSL1; NR1H3; HOXB7; SREBF1; SERTAD2; USF2; APEX1; SMARCD2; XBP1; NEDD8; ESRRA; HDAC2; CEBPA; ELK1; NKRF; HABP4; EDF1; HOXB2; SUV39H1; ERF; DNMT3B; NFKBIA; TTF1; MTF1; PAX8; SMARCA2; EGR3; TRIM28; RHOA; ATF4; ZNF384; ZBTB24; BCL6; ERCC2; HDAC5; TAF10; PREB; KLF12; KAT5; MAGED1; HDGF; PUF60; FHL2; DDX54; TSC22D1; RNF141; UBTF; JUND; HIVEP2; RUVBL2; HIPK3; FLNA; RERE; HLF; ASXL1; JUNB; TCFL5; CEBPG; SIAH2; TBL1XR1; YEATS2; AATF; MLXIP; YBX1; TGFB1I1; YBX3; CENPB; NKX2-2; TP53; MTA1; SETDB1; HR; MED24; ABL1; MSX1; ZMIZ2; ID2; FOXM1; NUP62; KLF4; SNIP1; BMI1; ZHX3; ZBTB18; JARID2; HES1; NRBF2; ZMIZ1; SMARCA4; PBXIP1; PATZ1; MED6; MEF2A; TMF1; ZNF580; BCLAF1; FOSL2; MYT1L; HOXC6; PMF1; HSF2; KDM5D; ZFHX4; POLR2A; MYC; SND1; SUB1; SIX2; HOXC10; MYCN; TRIM22; SAP30; HMGA1; TRIP6; AIP; FOXD1; NCOR2; SMARCA1; NFIL3; ZNF593; ELF1; TAF1D; ZNF468; ATN1; RBPMS; DDIT3; ENO1; PRPF6; RORA; STAT3; KLF6; TGFB1; BHLHE40; KDM5A; BCL3; GABPB1; ELK3; INSR; SMARCD3; KAT6B; STAT6; CALR; IRF8; CEBPB; PLAGL1; ZNF226; ATF3; PFDN5; PITX1; NR2F2; EZH2; ATF1; SOX10; ID3; CRK; STAT5B; GATA3; ECD