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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID63616 Doxorubicin GSE92742 SKB Human 24h 10uM EID0354
Types Number Response transcription factors
Up-regulation 274 ERBB4; CREB1; LHX3; HES1; SPDEF; TOX; MEIS2; MYBL2; ZNF85; FLI1; WT1; SOX2; ZNF816; ZNF415; ZFPM2; ZNF75D; BNC2; BARX1; TBX21; SSX1; TWIST1; CBX4; ST18; ZNF682; ZNF117; CDIP1; HOXB5; PRDM14; ZNF701; ZNF623; ZNF74; ZNF91; ID4; CHD2; SSX7; NR2F1; HDAC9; SHOX2; HSF4; FOXF2; TGFB1; ZNF224; CALR; HOXB2; SRY; TP73; VENTX; TTF2; NR5A2; E2F4; ZNF350; ZNF667; ZIC3; ZNF345; NFE2L3; RARG; ZNF835; SOX17; ZNF154; HOXB1; NR4A2; GLI2; TCF3; KLF15; ZNF440; ETS1; SALL2; MYBL1; PRDM1; CD3D; PSMC3; ZNF43; ZNF235; GATA6; ZNF215; ZNF141; HOXB6; SPI1; BPTF; ZNF675; ZNF695; NHLH2; BNC1; NFATC4; NKX2-1; TCF21; SRCAP; ARL2BP; NR1H4; THRB; ZNF232; ZNF665; HOXD3; VGLL1; ZNF257; ZNF180; GRIP1; NR5A1; POU4F2; ESR1; NEUROD1; RAD21; PEG3; SPIB; E2F1; SOX11; ZNF44; ZBTB44; ALX4; PBX3; ZBED2; DCC; ZNF589; E2F2; HLX; LIN28A; ZNF225; HOXD1; TRPS1; ZNF611; PGR; TSHZ2; DBP; FOXH1; CCNE1; HIRA; ACTL6B; KLF3; NCOA2; RBFOX2; RING1; TERF1; IRF6; POU4F3; NR2F6; ZNF551; ZNF544; PBX1; HHEX; STAT4; PIAS4; CUX2; NR1H2; ID1; PAX9; MYRF; ZNF331; HMX1; SOX3; GRHL2; AR; SOX18; OSR2; TCEA2; ELF4; PRDM12; ELK4; NANOG; TFAP2A; TBX1; VPS72; ZNF532; ZNF573; YAP1; CBX2; FOXA1; E2F5; KAT2B; ZMIZ1; NEUROG2; ZNF195; E2F8; TCEA1; FOXE1; ZNF492; ZBTB20; AEBP1; GFI1; INSM1; WNT4; ZNF107; FOXF1; ZNF273; HOXA2; CHD7; ATN1; ISL1; SUPT3H; PRDM13; L3MBTL1; RBBP8; ZSCAN9; TAL1; PHOX2B; SOHLH2; PCGF3; HIC2; TAF9B; CREBL2; THAP10; ARID3B; ACTL6A; BACH2; ATF3; ZSCAN18; IRF1; NFE2; IKZF2; FOXK2; CBX7; ATOH1; MXI1; ZNF177; ZNF239; MNDA; TGIF1; HOXA1; SIX3; EHMT2; SSBP2; KLF11; FOXM1; ID3; ARNTL2; CAMTA1; FOXA2; GATA1; KLF1; COPS5; CDK2; JUP; EHF; PAX6; LITAF; TRIB3; SOX13; HAND1; MYCL; PITX1; YEATS4; POU2AF1; GTF2A2; TDP2; CREG1; TP63; TCF7L1; MYCN; KLF13; DACH1; ZNF467; PAWR; IFI16; DNMT1; ZFP36L2; AES; ZNF264; HOXB13; GMNN; HMGB3; SMARCA1; CERS4; ZNF423; FOXJ1; CREB3L2; MEIS1; FOXG1; CITED2; LEF1; ZHX2; MEOX1; TOX3; ARNT2; BCL11A; TRIM22
Down-regulation 416 PUF60; SCAND1; ZMYM2; TSC22D3; NUP62; CRK; USF2; MYC; USP22; ERBB2; EGR3; NCOR2; FOXJ3; FOXO3; TBP; SNW1; PPRC1; ARID4A; MLX; PMF1; SSRP1; CENPB; SFPQ; BHLHE40; ING2; ATF1; BRPF1; KAT8; KAT5; CBX3; ZBTB11; NRIP1; ZHX3; SNIP1; BIRC2; WIZ; VGLL4; NCOA4; FHL2; SMAD2; NELFB; BRD3; MED24; PHF8; TRRAP; ECD; KAT7; PATZ1; NCOA6; ZFP64; ZMIZ2; SMARCD2; TRIM32; ZNF148; ASXL1; TRIM28; DDX54; GABPB1; CARM1; RBM14; ZNF672; SMARCA5; TADA3; MED23; PKNOX1; REPIN1; MED1; CTR9; ZNF263; YWHAB; XBP1; SMARCA4; GABPA; CREB3L1; STAT6; SF1; SETD2; ZNF408; SAP18; BCLAF1; BAZ1B; TRIP6; BRD8; RNF6; NFE2L1; ZFHX4; ATF7IP; PCGF2; HOXC6; ING1; SMARCC1; PHF2; BMI1; TMF1; REXO4; ZZZ3; SUV39H1; TP53; ZSCAN5A; RB1; HSF2; TBPL1; MED6; NEDD8; RUVBL2; KAT6A; ADNP; DPF2; RBM39; MED4; TAF10; ZNF574; KDM2A; GATAD2A; PIAS3; HDAC2; KDM5A; POLR2A; BATF3; BAZ1A; CUX1; ZNF629; NFKBIA; NFIL3; UBP1; NKX3-1; MAGED1; ZBTB18; DNAJC2; ZNF189; CENPF; CHD8; UIMC1; RUNX1; ZNF302; BCL3; PPARG; CCDC59; COPS2; MAZ; MED16; ZNF384; NSD1; AATF; ELK1; MNT; PSPC1; ASH2L; ZBTB24; PIAS2; EDF1; USP16; MYOD1; ZBTB40; ZNF764; TCF12; NFYC; ZNF143; YAF2; KDM5B; HNRNPD; NFKB1; ORC2; MAML1; ZNF292; IKZF5; HOXC10; MAX; PLAGL2; HMG20A; PSMD9; GCFC2; SREBF1; NFAT5; ZNF410; CDK8; NFKBIB; ZBTB38; ZBTB48; NONO; ATF4; HR; CREB5; IKBKAP; SMARCD1; HDAC7; MGA; ZNF226; NCOR1; MAF; DDX5; ZBTB43; BRF2; CNOT1; SMARCE1; TRIM16; SMARCA2; SAP30; BAZ2B; KLF2; TAF1D; ZBED4; SMARCC2; TSC22D1; AFF1; MEF2A; MLXIP; HCFC2; PCGF1; ZNF3; CHD1; RNF4; KLF4; PIR; NR2F2; NKRF; REST; JARID2; SETD3; TFE3; FOSB; C1D; PHF20; RELA; ZBED1; TBL1X; GTF3A; ZBTB1; GTF2IRD1; RBBP4; MED13; SP3; FOSL2; DR1; KLF12; CIZ1; KMT2B; YBX1; RNF111; SMAD7; TRAK1; ADNP2; NRF1; RNF10; SND1; ARID4B; CEBPZ; RBBP5; PAX8; RBPJ; TULP4; OLIG2; TGFB1I1; BRD4; PPARGC1A; FOXO4; ZNF24; FOXC1; KDM4A; ATF5; CLOCK; DEAF1; HMBOX1; PRPF6; UBE3A; AGO2; SOX4; MED7; TRIM27; PURA; KLF6; PDLIM1; IRF2; BBX; FOSL1; RELB; MEF2C; MAFF; SMAD4; NFIB; KLF10; NAB1; TRIP4; MNAT1; CASZ1; UBE2I; ETV1; CBFB; ID2; HDAC5; SIX1; ZNF443; BRD2; SATB2; STAT5B; TTF1; ING3; HMG20B; HSBP1; MBD2; RNF141; ZNF146; NRBF2; SIM2; HDAC4; NFATC1; FOXN2; VDR; SIX2; ELF1; SAFB2; MSX1; BATF; IRF8; THAP1; HMGXB4; ZNF473; TSC22D4; TSC22D2; PBRM1; STAT1; HIVEP2; WHSC1; SREBF2; TFCP2; CCNA2; LPIN2; DNAJC1; EGR1; ZFX; ZNF512B; STAT5A; TEAD1; APEX1; ZNF783; MMS19; DRAP1; TFAM; RUNX3; ENO1; ARID1A; WWTR1; HDAC6; MEN1; ZEB2; SERTAD2; HMGA2; ZNF12; ALX1; BASP1; CRY1; IRF7; RFX5; TCERG1; PTTG1; RARA; MITF; TXNIP; MSC; BCL10; HTATIP2; RERE; HIVEP1; RNF14; FOXD1; SPEN; HDAC1; FLNA; SOX9; HEY2; SMAD3; SUB1; SATB1; ZNF267; SIAH2; EZH2; SP110; TFEB; CHD3; NPAT; BLM; RLF; NR4A1; BTG1; CHD9; IRX5; TLE4; SP100; RNF138; TBL1XR1; MAFB; ABL1; EYA1; HLTF; DDX17; ELK3; ZNF468; KAT6B; SMARCD3; ZFP36L1; RORA; CRYM; CTNNB1; SMAD1; MXD4; AHR; TLE1; NFX1; DNMT3B; BCL6; ZNF281; TCF4; HEY1; ETS2; EYA2; ETV5
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