Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63614	Betahistine	GSE92742	SKB	Human	24h	10uM	EID0354

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	ZNF589; IRF8; NKX2-1; FLI1; HOXB6; ST18; ERBB4; NR1H4; HOXB5; ZNF141; TULP3; SOX3; RBFOX2; HOXB2; MYBL2; ZNF117; TFDP2; ZNF22; INSR; ZNF232; SALL2; POU2AF1; NANOG; SOX11; OVOL2; HOXD1; ISL1; PBX3; NR1H2; MYBL1; NFE2; MEIS2; FOXA1; TCF7L1; NEUROD1; TOX3; ILF2; CUX2; KLF11; WT1; TRIB3; VPS72; TFAP2A; HHEX; ZBED2; FOXF1; KAT2B; FOSL2; SOHLH2; INSM1; CEBPD; E2F8; CTBP2; TERF1; ZFPM2; ID1; LIN28A; ID4; MECOM; FOXG1; GATA6; TLE4; MNDA; TCF21; TCF4; RBPMS; BCL11A; ARNT2; DACH1; IFI16; BASP1; NFATC3
Down-regulation	103	BIRC2; ATF6; KDM4C; USF2; NFE2L2; JUNB; SMAD2; NFYA; NFKBIB; KLF6; NR4A2; BATF3; BCLAF1; BHLHE40; HIVEP2; UIMC1; LHX6; MBD2; FOSB; TLE1; NR4A1; KDM5B; BRPF1; RUNX1; BATF; NFE2L1; DMTF1; BRD2; MED24; IKZF5; ZMYND11; CTR9; TADA3; RNF14; TOB1; ATF3; ETV1; NCOA6; SUV39H1; HOXC6; MED23; EGR1; PIAS2; PAX8; BAZ1A; ZMIZ2; TRIM16; STAT5B; FOXD1; SFMBT1; MEF2A; NAB1; RNF141; MSX1; HTATIP2; DDX5; KAT7; ID2; COPS2; BTG1; HMGA1; BLM; STAT5A; BMI1; EDF1; ZKSCAN1; TSC22D1; YWHAB; RBL2; AFF1; PRRX2; NFATC1; DNMT3B; SMARCA2; KLF2; CREB3L1; RBBP4; FOSL1; HOXC10; KLF9; PRRX1; MED1; PURA; EYA2; CRY1; NR2F2; MTA1; MEF2C; PCGF2; IRF7; FOXC1; ZBTB38; SIAH2; STAT1; KDM5D; ZBTB18; NKX3-1; ELF1; ZNF652; TSC22D2; IRX5; LEF1; MEIS1