Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63608	Tolbutamide	GSE92742	SKB	Human	24h	10uM	EID0354

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	SPDEF; ERBB4; SOX2; CREB1; HOXB2; MYBL2; ZNF623; PBX3; MEIS2; ZNF74; NKX2-1; HOXB5; ID1; FOXM1; NR2F6; BNC2; HIRA; ZNF195; HOXB6; ZNF232; RBBP8; POU2AF1; RBFOX2; CDIP1; ZNF552; ZMIZ1; BARX1; MED14; RAD21; ZFPM2; VPS72; INSR; ETS1; PGR; TULP3; ZNF532; BNC1; ST18; ZIC3; POLR3C; SALL2; HIC2; PRKDC; ATN1; SUPT3H; ZNF589; ASCL1; ZBED2; NR1H4; FOXK2; GATA6; AR; TCF21; TTF2; NR2F1; WT1; ZNF611; ZNF117; PBX1; CUX2; RXRA; NANOG; HDAC9; NFE2L3; THAP10; TCF7L2; SOX11; TRIB3; TFAP2A; SIX3; MYBL1; HLX; GRHL2; SOX17; GTF2A2; ISL1; E2F8; BACH2; NEUROD1; CHD7; CTBP2; NR5A2; TCF7L1; PEG3; NFE2; ZEB1; ZNF43; TCEA1; HHEX; TEAD4; ILF2; LIN28A; FOXE1; IRF6; MYRF; HOXD1; BCL11A; MNAT1; MECOM; FOXF1; IFI16; TP63; ZNF423; ARNT2; DACH1; TRIM22
Down-regulation	157	VGLL4; USF2; ARID5B; ZNF148; EGR3; SCAND1; NUP62; ZNF226; BRD2; BATF3; ARID4A; BRPF1; SUV39H1; NEDD8; ZMIZ2; CRK; SMAD2; HOXC6; TADA3; BCLAF1; ORC2; ZNF672; MAF; NR1H3; PHF8; ZBTB11; DDX54; TBX2; ATF1; PEX2; JARID2; NFKBIB; SNW1; TBP; MSX1; ZNF266; BMI1; RELB; ZNF263; TRIM32; NFAT5; ZIC1; KAT6A; BRD8; PDLIM1; SMARCA2; BCL3; TRIM28; PATZ1; ING2; IKZF5; SAP18; ZHX3; ADRB2; PSPC1; NAB1; KAT7; TBPL1; OLIG2; ERBB2; SFPQ; EDF1; DRAP1; TAF1D; SMARCA4; NFATC1; TRIP6; MED1; HOXC10; PHF1; BATF; HSF2; ZSCAN31; MED23; ZBTB18; ZFHX4; CBFB; TSC22D1; BAZ1A; RNF141; IRF7; TSC22D4; MAFB; HDAC1; NELFB; STAT6; KLF9; CARHSP1; MITF; ZNF443; CTR9; PQBP1; BAZ2B; FOXC1; HLTF; MSC; NR2E1; RUNX1; RUNX3; ZNF281; NFKB1; PURA; TXNIP; SFMBT1; STAT5B; PIAS2; NCOA4; POLR2A; EGR1; NCOA1; ID2; MBD2; KDM2A; PRRX2; RELA; NFKBIA; FOXD1; ING3; SATB1; HSBP1; TOB1; KAT6B; SPEN; CRY1; RBL2; IRX5; MEF2A; NR2F2; MXD4; KLF2; HDAC6; TCFL5; FOSL2; FOSB; BASP1; CTNNB1; KDM5D; ZBTB38; ARID4B; IRF5; PCGF2; PHF20; BBX; LMCD1; TSC22D2; HEY1; FLNA; GTF3A; TAF10; ELF1; STAT5A; EZH2; HOXC4; MAGED1; BTG1; TLE1; SIAH2