Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63461	Mexiletine	GSE92742	SKB	Human	24h	10uM	EID0354

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	CREB1; GLI2; ZNF623; POU2AF1; TOX; BNC2; SOX2; ERBB4; RAD21; CDIP1; ZNF195; BARX1; HIRA; ZNF682; TCEA2; PLAGL1; ZFPM2; RBFOX2; WT1; IRF8; ZNF835; BNC1; ZNF74; SPDEF; ZNF345; ZNF232; FOXF2; PGR; ZMIZ1; TGFB1; ETS1; CD3D; FOXO1; TCF7L1; ZNF44; SALL2; POLR3C; CUX2; NR2F6; MED14; ZNF117; MEIS2; ZBED2; YEATS2; FOXK2; NCOA2; RBBP8; HOXD1; ZNF589; FOXM1; ZNF544; NKX2-1; WWP1; MDM2; ZNF611; TERF1; SP140L; NR1H2; NAB2; GATA6; L3MBTL1; ST18; ZNF43; EHMT2; NR2F1; SOX13; TCF7L2; ZIC3; CERS4; PRKDC; ISL1; ZSCAN9; ZFP36L2; SMARCA1; HOXB13; SOX17; TRIB3; DNMT1; CBFA2T2; TCF21; MYBL1; YEATS4; TCEA1; KLF11; VPS72; CREB3L2; BACH2; ILF2; TFAP2A; IFI16; IRF6; CBFA2T3; ID1; TDP2; MEOX2; MNDA; AEBP1; ZEB1; GMNN; JUN; TLE4; HHEX; BCL11A; PEG3; ID4
Down-regulation	135	USF2; CRK; ARID4A; GABPA; TAF12; BRPF1; NUP62; MLX; SNW1; IKZF5; SUV39H1; PDLIM1; TRIM32; EDF1; ATF1; ZNF672; TOB1; ING2; ASH2L; BATF3; DDX54; SFPQ; UIMC1; BMI1; ZBTB18; HIPK3; HOXC6; YWHAB; ORC2; OLIG2; ZNF226; HSF2; KAT7; BRD2; YAF2; ZMIZ2; MYCBP; MED1; MSX1; BAZ1A; KLF4; ELK1; KAT6A; NFE2L1; HTATIP2; TADA3; STAT5B; SMARCA2; CHD1; RNF4; BCLAF1; PPARG; HSBP1; TBP; JARID2; CREBZF; BATF; FOSB; PSPC1; RNF141; CREB3L1; ID2; KDM5A; PURA; LMCD1; RBBP4; DRAP1; RBM14; SAP18; KDM2A; CRY1; STAT3; ZIC1; SATB1; PIAS2; ELF1; NFKBIA; NR2F2; HOXC10; SAP30; MEF2C; TRIM28; KLF5; PCGF2; ZEB2; MITF; IRX5; DDX5; TAF10; TXNIP; RUVBL2; TSC22D2; PIR; FOSL2; YBX1; ING3; ZNF24; FOXC1; ZNF281; TRIM16; NFKB1; BASP1; TCFL5; NCOA4; NKX2-2; BTG1; NFIB; MXD4; AFF1; DNAJC1; KLF9; IRF7; ZNF267; GTF3A; KLF2; TCEB2; RFX5; BBX; SIAH2; SPEN; KLF6; ETS2; CITED2; SMAD3; RBL2; KAT6B; HLTF; EZH2; MEIS1; MAFB; DAXX; MAGED1; KDM5D; ZNF131; NFATC3