Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63397	Alfuzosin	GSE92742	SKB	Human	24h	10uM	EID0354

Response Information :

Types	Number	Response transcription factors
Up-regulation	153	ERBB4; SPDEF; HOXB6; CREB1; WT1; HOXB5; SOX2; HOXB2; HSF4; BARX1; ZNF85; BNC2; ZNF350; ZNF195; ZNF224; ZNF91; EN1; CEBPG; ZNF219; MYBL1; NCOA2; ZNF232; VPS72; TCEA1; FOXK2; MYBL2; ZFPM2; MEIS2; CDK2; ZNF74; E2F4; COPS5; HIRA; ID4; ZNF611; PBX3; ZNF532; TWIST1; NR2F6; MNDA; POLR3C; ZNF117; TGS1; CDIP1; ZNF544; NFE2; ST18; MYRF; SSBP2; ZNF180; RAD21; TCF7L2; RBBP8; HDAC9; PRDM14; ATF3; SALL2; TCF7L1; KLF1; TERF1; MED14; L3MBTL1; SP140L; CUX2; KLF3; IRF1; WWP1; ZNF665; IRF8; KAT2B; TTF2; ZEB1; ZMIZ1; GATA6; PSMC3; HMGB3; NR5A2; HOXD3; RARG; ZNF43; ZNF273; PIAS4; CD3D; NR2F1; E2F8; ZBED2; NFE2L3; SRY; SOX17; THAP10; PAWR; CREB3L2; TCF21; SSX1; ZNF44; TFDP2; ZNF33B; ZFP36L2; OSR2; HOXD1; PEX14; CCNE1; LIN28A; ETS1; TFAP2A; SOX11; ZIC3; TRIB3; ENY2; YEATS4; MXI1; NANOG; PRKDC; POU2AF1; DNMT1; HIC2; CERS4; EHMT2; PEG3; NR1H2; SIX3; TRPS1; SUPT3H; ID1; TRIM22; BCL11A; MED17; TBX3; TAL1; ZNF467; DDIT3; MYCL; MYCN; ILF2; BHLHE41; FOXE1; ESR1; GRHL2; GMNN; CHD7; TDP2; SOX13; IRF6; SOX9; HHEX; ZNF423; IFI16; CREG1; KLF6; TLE4; PBX1; PAX6; NFATC3
Down-regulation	167	ARID4A; USF2; TADA3; ARID5B; SFPQ; SNIP1; LHX6; SMAD2; ZNF384; ATF1; CRK; ZMYM2; ERBB2; PHF8; PATZ1; SNW1; NAB1; NRIP1; ELF2; YBX1; NUP62; BMI1; NPM1; KAT5; BRF2; HOXC6; YWHAB; SATB2; TRIM28; HSF2; BAZ2B; SETD2; NELFB; SUV39H1; TBX2; ZFHX4; SMARCA5; RUVBL2; CHD3; PDLIM1; BRPF1; TCEB2; ZFY; ZMIZ2; HOXC10; ZHX3; DDX5; TXNIP; KDM5D; PSPC1; JARID2; ZEB2; IKZF5; NFKBIB; TGFB1I1; SMAD7; ELK3; MAZ; MSX1; BASP1; COPS2; PURA; KAT7; EDF1; NFYC; RNF141; CREB3L1; BRD8; TRIM32; GTF3A; NONO; TBP; KDM5A; RNF6; STAT5B; NFAT5; HIPK3; OLIG2; SMARCA2; RNF4; HDAC1; RBM14; DRAP1; PIAS2; BRD2; PHF1; BCLAF1; TRIP6; POLR2A; ZBED1; SAP18; CDK8; NR1H3; ZBTB18; HSBP1; TSC22D2; TRIM16; MAF; MED1; MITF; NCOA4; NLK; HMGA1; NFKB1; HMBOX1; ZBTB1; ZBTB38; ZIC1; MED23; ALX1; ELK1; CEBPA; NCOA3; TSC22D1; CTBP1; ZNF226; ZMYND8; REPIN1; TCFL5; FOXO3; NCOR2; XBP1; BBX; PHF20; FOXO4; TCERG1; PPARGC1A; HDAC6; MED24; ELF1; MAGED1; KDM2A; MYCBP; RBL2; MYT1L; DDX17; ZNF24; NR2F2; ZNF580; GTF2IRD1; FOSB; TCF12; RBBP4; HEY1; NFATC1; MBD2; TAF10; MXD4; ERG; HLTF; IRX5; ARID4B; KLF4; BATF; HOXA10; ID2; FOXC1; NFIB; NFX1; STAT5A; MEF2A; NRBF2; TBL1X; ZNF281; KLF2; NKX3-1; ZNF131