Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63366	Phentolamine	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	RB1; KLF5; JAK2; GABPA; EP400; DNAJC1; HIRA; ORC2; PURA; TXNIP; PPP1R13L; ZHX3; KLF2; SKI; PRRX1; PSPC1; PITX1; ATF6; POU3F2; HOXA5; PPARGC1A; NFKB1; SOX4; STAT5B; ELF1; TFEB; SAP18; YAF2; BMI1; ZBTB18; HIVEP2; MEF2A; SOX10; BRD2; KMT5A; NCOA1; RNF141; CEBPA; TBPL1; MEF2C; ID3; HOXA7; WHSC1; UBE2I; PEG3; NFKBIA; HDAC4; RNF14; MEIS1; MAX; ELK3; RELB; HSF2; TSC22D1; ZBTB38; BTF3; ZNF528; RUVBL2; BIRC2; PBRM1; EYA1; SMARCA2; SMARCE1; ELK1; PSIP1; FOXO3; KLF4; TCF4; RUNX1; MAFF; BHLHE40; HOXD11; PQBP1; NCOA6; NAB1; SCAND1; CTNNB1; MNAT1; DLX5; HSBP1; PIAS2; RBBP4; TBP; ZMYM2; TGIF2; TP53; ZNF148; ID1; HEY1; TRIM29; NONO; PAX6; HEY2; TP63; BACH2; DACH1; VDR; HNRNPD; KLF6; RXRA; TCEB2; POU4F1; TLE1; YBX1; BCL3; CARHSP1; EDF1; NFATC1; CCNE1; IRF8; FOSB; HDAC1; PTTG1; NFE2L2; TSC22D2; TOB1; TBX2; MSX1; BASP1; MAF; LEF1; RHOA; HMG20B
Down-regulation	107	HOXC10; ZIC3; TRIP6; LIN28A; PHIP; SMARCA1; ZNF44; PCBD1; SSX1; ARNTL2; ELF5; PBX1; NLK; THAP11; TRIB3; KLF13; TRIM22; TAF6; ATF5; ZNF580; RBPMS; EMX2; SALL2; SOX3; TRIM24; ZNF195; RBBP8; EN1; RREB1; GATA6; INSR; CRYM; ZNF215; CREB3L2; NANOG; ZNF232; ZNF124; MYB; ZNF611; SIX3; HOXD1; ZKSCAN1; IRF9; ERBB4; DNAJC2; AR; FOXG1; TFAP2C; MED17; HMGN3; NFE2L3; ZNF43; MYRF; E2F5; LMCD1; NR5A2; ZNF239; CRK; SOHLH2; BNC2; MEIS2; ARID1A; STAT6; E2F8; ZNF415; ZNF85; HTATIP2; SMAD7; SPDEF; THAP10; CREG1; MYCL; DMTF1; HDAC9; MNDA; ZNF107; ESR1; ZSCAN18; INSM1; CUX2; ACTL6A; ZNF551; ZBTB16; ZNF117; TERF1; CDK2; SSBP3; ZNF394; TAL1; MYBL1; PIR; HOXB2; IKBKAP; IRF4; VPS72; TGFB1; ZNF589; MKL2; ZNF91; IRF6; ABL1; ERBB2; TBX3; RAD21; PBX3; ATF3; KDM5D