Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63361	Tolbutamide	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	177	XBP1; TRIM16; BAZ1A; TRIP6; ZBTB11; BMI1; C1D; FOXJ3; BAZ1B; HDAC6; BATF3; BCL10; PHF2; CTR9; ELK3; NR2F2; TRIM22; SMAD4; RNF6; BCL6; IRF2; TBX2; NUP62; ZNF432; CBFB; CDK7; TAF1D; ZFP64; UBP1; CHD9; ARID4A; ZNF131; RB1; SMARCA5; RNF111; REST; MTDH; GTF2IRD1; ZMYM2; SMAD2; ZNF217; EZH2; SOX11; FOXD1; SP100; ZZZ3; ZBTB38; ELF1; CHD3; MED4; CRY1; SMAD7; HIVEP2; KLF2; ATF6; ING2; TSC22D3; ARID4B; BAZ2B; MYT1L; DNAJC2; SPEN; PSPC1; BRD8; PRMT2; ZBTB24; MEN1; PSIP1; BIRC2; ECD; NFE2L1; KLF5; ID2; RBM14; AFF1; TCF12; TRIM32; SETD2; TAF9; FHL2; COPS2; TMF1; RUVBL2; RERE; ZNF143; CREB3L1; HMG20A; MED6; NCOA4; MEOX1; CRK; RBBP5; BATF; MED13; BCL11B; RNF10; ZBED1; DNAJC1; RBPJ; HNRNPD; NCOR2; BTF3; TADA3; NFKB1; ZNF468; TCERG1; KDM5D; NCOA3; BHLHE40; SMARCA4; MYC; NRBF2; PIAS3; CCDC59; TAF7; RUNX1; DAXX; ZNF692; ATF1; ZNF23; ATF2; ZNF146; TLE1; NEDD8; SIX1; ETS2; ELK1; SP3; MECOM; SCMH1; DPF2; HOXB7; CBX3; ERBB2; ZNF587; MDM2; GTF2A2; MAGED1; SMARCD3; TRAK1; ZNF189; MSX1; TLE2; PHF20; YBX1; TXNIP; CUX1; YWHAB; PCGF2; HOXB6; IKBKAP; MNAT1; TRIM28; USP22; CREBL2; RBPMS; MED1; ELF3; CITED2; BASP1; SUB1; SAP30; STAT6; ETV5; IRF8; SMAD3; TGFB1; HDAC2; TLE4; EDF1; VGLL4; POU2AF1; TSC22D2; HOXC6; HEY1; SALL1; RHOA
Down-regulation	137	DACH1; CD3D; HMGB3; TFAP2A; KLF9; PRDM12; RORB; LIN28A; TRPS1; PRDM13; CEBPD; PHIP; HSF1; ZNF331; DLX2; EN1; TFAP2C; NEUROD1; ZNF266; SMARCA1; JUND; TFDP2; KLF11; NKX2-1; ZNF711; ZIC3; IRF6; WT1; WNT4; ZNF345; SALL2; BNC1; SOX18; NR4A2; PRDM14; SOX3; NR4A3; ZFP36L2; INSM1; RFXANK; PGR; EHF; CDX1; MXI1; AR; CIITA; HDAC4; HAND1; HOXC4; FOXL2; NCOA1; XRCC6; VGLL1; MED25; ZNF571; TAF9B; HIC2; TBX3; ZNF232; TOX; ZNF573; DBP; ZNF426; SSBP3; ZNF611; ST18; ZNF215; TAL1; SLC2A4RG; AEBP1; HBP1; SOX13; SMARCB1; GATA6; GFI1; RREB1; CBX6; ZNF43; ZNF235; ZBED2; CBX4; CREB3L2; NAB2; MYCN; SIX3; NR5A2; HOXD3; ZNF350; CHD7; FOXA1; BTG1; MAF; MYCL; KLF13; TGIF2; ZNF415; LMCD1; FOSL2; OSR2; ARID5B; CDK2; BNC2; NFE2; BCL11A; JUN; ZNF136; PAX6; CEBPG; ZNF93; STAT1; ATF3; HEY2; IRF9; ZNF264; RAD21; MYBL2; CTBP2; SOHLH2; CALR; SPIB; NFATC4; RXRA; MLXIP; ERBB4; ZMYND8; ESR1; ID4; JUNB; VPS72; PBX3; TOB1; JUP; LEF1; HHEX; ZBTB20; NFATC3; ZNF589