Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63349	Losartan	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	HDAC6; ELK3; NKX3-1; NFIC; TXNIP; MEOX1; IRF2; ZSCAN16; SMAD1; ISL1; BCL6; TRIM32; E2F2; RELA; PEG3; HOXD11; HIPK3; NFIB; ZNF3; PFDN5; FOXN3; KLF5; TCF12; MECOM; RBFOX2; DDX5; FOXO1; NFYC; BCL11B; CBX6; BIRC2; KAT5; ZNF516; HSBP1; NR2F2; NR3C2; KLF7; TFAP2C; NEDD8; MBD2; HMGA1; SMARCE1; PLAG1; SMAD3; ELF1; AES; ZNF654; BTG1; MAFB; WNT4; SAP30; FOXA1; FLNA; SIX2; MEOX2; PCGF2; POU4F1; HIPK2; KLF2; CCNH; VEZF1; PURA; TBL1X; TSC22D2; FOXO3; DLX5; NCOR2; MNAT1; CBFB; DNAJC1; PSIP1; ZBTB38; TGFB1I1; LITAF; SIX1; EDF1; TWIST1; FOSL1; CUX1; ATF5; ZFP36L1; OSR2; MAGED1; MSX1; CDK2; ARID5B; TCF4; HOXC6; HMG20B; ERBB2
Down-regulation	51	CDK7; IRF1; LIN28A; ZNF512B; GATA6; TAF9; TRIM22; TFAM; CDC5L; RBPMS; MED24; CTR9; MYB; PRKDC; BCL11A; NR4A3; HOXB2; ID4; CEBPG; HOXD1; PLAGL1; DNAJC2; ZNF224; ALX1; PBX2; ZNF329; CIR1; CREB3L2; TERF1; DNMT3B; MTA1; GATAD2A; WT1; NCOA2; ZNF22; ZSCAN18; RBM39; MNDA; LMCD1; FOXF2; MXI1; HMGB2; WWP1; ZNF117; RAD21; TGIF1; ZBTB20; KDM5D; ZNF589; EGR2; HHEX