Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63302	Protriptyline	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	131	XBP1; BCL10; C1D; BMI1; MED7; CHD9; TSC22D3; ARID4B; NLK; TRIM22; SP100; FOXJ3; RNF6; SMAD1; ZBTB11; MED4; ZNF468; REST; BAZ1A; TAF1D; TRIP6; BIRC2; RAN; USP22; HABP4; HDAC6; MEOX1; ZNF432; NUP62; STAT1; ZBED1; TEAD4; ERG; ATF2; KLF2; CRK; HOXC10; TAF9; ZNF44; HOXA10; PPARGC1A; FHL2; SMARCA4; SMAD2; CRYM; MTDH; SPDEF; AHR; RUNX1; MED6; NFAT5; CBX3; PCBD1; RSF1; RORA; UBE2B; TSC22D4; TRIM16; PHF20; TMF1; KAT7; HIVEP2; CUX1; TAF7; BATF3; HTATIP2; ZMYM2; UBP1; CBFB; NFIB; FOXO1; NPAS2; BHLHE41; KLF5; NCOR2; TSC22D1; YAP1; RBPMS; TBL1X; ZNF84; REPIN1; TLE1; PEG3; SIX2; MYC; PQBP1; COPS2; EGR3; NR2F2; HDAC7; DNAJC2; HIF1A; ZKSCAN1; ZNF226; CREB5; C1QBP; SNAI2; NFATC3; HOXD1; CREB3L1; FOXC1; DMTF1; HOXB7; SIX1; EMX2; SMAD3; SSBP2; ETV5; EDF1; MEF2C; ZNF12; ATF4; PIR; TOX3; TRIM29; HLF; MNT; ELF3; HES1; PCGF2; HDAC1; ENO1; SUB1; TP63; WWTR1; KDM5D; YWHAB; ZFP36L1; BASP1; RBPJ; HOXC6
Down-regulation	124	LIN28A; ZIC3; HMGB3; CD3D; SMARCA1; RING1; LHX3; HIRA; SUPT3H; ZKSCAN4; ZNF512B; TCEA2; SIAH2; ZNF232; MED24; IRF6; TFDP2; SOX3; RFXANK; ZNF274; HEY2; HAND1; ZFP36L2; TCF21; PRDM10; SALL2; DACH1; EN1; VGLL1; RARG; ZNF580; DBP; PRDM14; INSR; ZNF345; NKX3-2; NKX2-1; ZNF516; DNMT1; HLX; FOXL2; ZNF93; PHIP; MYB; MXI1; CHD7; ZNF215; GFI1; PITX1; ZNF711; SRCAP; TAF5; ZNF331; SLC2A4RG; PHF1; WNT4; CALR; GRHL2; ZNF74; FOXF1; DLX2; BTAF1; TFAP2A; TGIF1; PSMC3; JUN; SMARCB1; NCOA1; GATA6; TAL1; AEBP1; PAX6; WT1; HIC2; AR; NR1H2; MTA1; KLF1; SOHLH2; CTNNB1; BNC2; ZNF467; CDK9; TWIST1; SOX11; ZSCAN18; TOX; ID1; PBX2; FOXA2; TBX3; BCL11A; FOXE1; KDM5C; ERBB4; HHEX; FOXJ1; ZNF91; MYCL; BTG1; NR2F1; ARID5B; TRPS1; PTTG1; CNOT3; ID4; ZNF589; NKX2-2; IRF4; ZNF264; MEIS2; TBX2; TCF4; POU2AF1; LMCD1; MNDA; MSX1; OSR2; SOX17; SALL1; JUP; KLF4; ATF3; MAF