Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63283	Guanfacine	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	180	TAF1D; PEG3; ZMIZ2; USF2; FOXD1; EP400; BCL6; BCLAF1; FOXJ3; BAZ1A; MSX1; ORC2; UBE2I; ZNF783; SIX1; POLR2A; NFAT5; PCGF3; MXD4; NRIP1; REPIN1; HOXC6; SOX10; SREBF1; HOXA5; POU3F2; ZHX3; PKNOX1; ZBTB1; NFIL3; SPEN; MAGED1; ZBTB18; ARID4A; TULP4; MED24; MSC; BIRC2; ATF6; PMS1; ELF1; ENO1; ARID4B; MYCBP; RUVBL2; NFATC3; SUV39H1; KAT6A; SIM2; BRPF1; HIVEP2; MYOD1; MED1; EDF1; NFKB1; RBM14; RELB; SMARCE1; USP16; SETD2; ZNF516; NR2F2; TCERG1; KDM5A; MNAT1; MLLT10; CASZ1; TBL1X; PARP1; BHLHE40; ERG; RNF4; HLTF; PURA; HMBOX1; UIMC1; MBD2; HOXA7; ZNF384; SMARCD2; NEDD8; RNF141; KDM2A; SMARCA4; TEAD1; TRIM28; HOXA10; CEBPA; GATAD2A; BRD3; ZBTB38; NFIB; NCOR2; SFPQ; ELK1; DRAP1; FOXO3; FLNA; ZNF226; BASP1; BANP; TAF10; SERTAD2; MZF1; PAX5; CREB3L1; KLF7; BCL3; APEX1; TBP; DDX17; ZNF3; MYCN; WHSC1; PIAS2; WWTR1; NFKBIA; KLF2; FOSL1; SCAND1; TCF4; PITX1; USP22; PIAS3; MDFI; TSC22D2; HDAC7; DDX5; HSBP1; HNRNPD; MED23; CBFB; ZNF146; TXNIP; KLF5; SAP18; BRD2; POU4F1; STAT1; BTG1; KAT6B; ERBB2; ZMYND8; MYC; SMARCA2; NELFB; RCOR1; TSC22D4; TLE4; FOXO1; BBX; PCGF2; YBX1; ZNF302; NFATC1; NR1D2; VGLL4; TCEB2; CARM1; FOXL2; BHLHE41; RUNX1; TRAK1; SOX9; HOXB7; HDAC1; ZFHX4; ASCL1; ID3; CUX1; TSC22D1; CCNE1; DAXX; KLF4; ATF4; HEY1; PTTG1; ATF5; HMG20B; KDM5D
Down-regulation	164	TRIB3; ZNF232; TFAP2C; CD3D; LIN28A; SSX1; NKX3-1; ZNF217; TFAP2A; NFYB; DNMT1; FOXI1; NR1H4; ZIC3; ILF2; SOX18; BNC1; ZNF354A; TOX; ZNF74; ZNF32; GTF2F1; ZNF43; SOX3; SUPT3H; ZNF665; ZNF473; SRY; GMNN; ATF3; ZSCAN18; RREB1; SALL2; ZNF345; HDAC9; HIC2; TDP2; ZFPM2; TP73; MKL2; RBPMS; HOXD1; IFI16; DEK; ZBED2; ZNF85; SIX6; CREB3; THAP11; FOXF2; TERF1; JUN; ZNF623; NCOA2; HMGB3; E2F8; SOX13; MYBL1; RAD21; PBX2; TAF5; PRDM14; ZNF136; PBXIP1; JUP; NFE2; TBX1; CRYM; FLI1; ZNF557; HLF; BRD7; ARID5A; SUMO1; HOXB2; POLR3C; PSMC3; NR4A2; ZNF195; TRIM24; PBX1; ZFP36L2; CBFA2T3; ZHX2; TCEA2; PHIP; ZNF91; SPDEF; ZNF124; ARID5B; CREBL2; ZNF215; WT1; LITAF; MYCL; BCL11A; ZNF239; CDK2; ZNF140; ZNF415; ZNF331; FOSL2; MYBL2; PRDM1; ZNF394; ZNF180; BNC2; CUX2; NANOG; NR4A3; NFE2L3; ZNF467; IRF6; PNRC1; CREG1; CTBP2; ZNF350; FOXE1; TAL1; WWP1; SSBP3; MED17; TRPS1; SRCAP; THAP7; DACH1; ZFP36L1; NAB2; HMGB1; ERBB4; ZNF430; FOXK2; IRF9; CRK; ID4; SOX17; SOHLH2; CBX7; MEIS2; CNOT3; RBBP8; NR5A2; HHEX; GATA6; NR2F1; NFATC4; ZKSCAN1; SNAI2; MNDA; FOXF1; TGFB1; SALL1; RUNX3; SSBP2; CALR; NR1H2; VPS72; EGR2; POU2AF1; CITED2; DLX2; LEF1; HES1; TBX3