Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63281	Aliskiren	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	FOXJ3; ZMIZ2; PPARD; TBL1X; ZBTB18; SETD2; FOXD1; POLR2A; CENPF; KDM4A; ELK1; MTF1; BCL6; ZNF783; RBM14; NR2F2; WHSC1; DPF2; EP400; BANP; HOXA5; XBP1; PIAS2; KDM5A; SOX10; IRX4; ELF1; MXD4; BIRC2; EDF1; NCOR2; UBE2I; PHF8; TAF1D; SUV39H1; LPIN2; ZBED1; SMARCA5; RBBP5; TRIM28; RERE; FLNA; SPEN; BATF; DDX54; PURA; NFYC; RUVBL2; DRAP1; SF1; BRD3; ELK3; BHLHE40; SMARCA4; CASZ1; HNRNPD; MSX1; FOSL1; NFKB1; TRIM32; RUNX1; MSC; INSR; CITED1; KDM2A; NUP62; KAT6A; BRD8; BCLAF1; MDFI; EWSR1; FHL2; GATAD2A; BAZ1A; RELB; CTR9; USF2; BCL3; CSDE1; RNF4; PARP1; MED16; ARID4B; BMI1; KMT2A; ZNF148; SMARCD2; ENO1; TSC22D2; SFPQ; RUNX3; ZNF24; RBPJ; NFIB; ZZZ3; ZNF146; SOX9; FOXO3; MED1; UBP1; PCGF2; MAFB; PEG3; SIX1; WWTR1; CEBPA; MKL1; SCAND1; NELFB; HDAC1; TSC22D4; HOXC6; SMARCA2; PSIP1; SP3; APBB1; PIAS3; WIZ; HIF1A; BBX; YWHAB; SMARCE1; CREB3L1; TADA3; ERBB2; ZNF516; CBFB; TAF10; CBX3; KAT6B; MAGED1; ETV5; CRK; ZMYM2; BASP1; HLTF; ABL1; DNAJC1; RCOR1; ZBTB38; USP22; FOXL2; RBPMS; TCEB2; FOXO1; NCOA6; PATZ1; KDM5D; TGFB1I1; RXRA; VGLL4; PTTG1; NFATC1; HOXA10; TP53; MNT; FOXO4; NRBF2; ZIC1; ATF5; HMG20B
Down-regulation	153	TRIB3; LIN28A; ZNF232; HIC2; PHIP; DNMT1; TDP2; ZFPM2; ZFP36L2; ZNF273; DACH1; SSX1; TOX; TFCP2L1; ZNF345; ILF2; HSF1; ZNF195; EHF; ZNF33B; SOX18; ZNF225; YBX2; CREB3; ID4; ZNF117; ZNF571; TERF1; GMNN; ZNF354A; PFDN5; ERBB4; TFAP2C; ZNF184; ZNF711; POLR3C; OVOL2; IRF6; ZNF75D; CDX1; NCOA2; ATF3; HIRA; ZNF268; EN1; KLF13; ZNF423; TFEC; SIX6; AEBP1; ZNF557; CD3D; RREB1; ZNF623; ZNF22; ID3; JUP; HDAC9; NR3C2; ZIC3; SRCAP; MED14; TFAP2A; TCF21; JUN; TCF7; TBX3; ZNF180; KLF11; ZNF74; REL; HOXD1; ZNF107; MYB; SNAI2; ZNF32; ZNF140; TCEA1; MYCL; ZNF215; HBP1; TDRD3; ZBED2; FOXF2; PBX1; ZNF85; ZNF331; ELK4; KLF9; CBFA2T2; TAL1; CUX2; CBX4; FLI1; ARID5B; ZNF394; CIR1; EPAS1; PAWR; CDK2; LEF1; NANOG; NFE2; ZNF239; THRA; CREG1; ZNF652; POU4F1; ITGB3BP; BACH2; THAP7; SOX17; MEIS2; MECOM; BCL11A; ZNF12; E2F5; SPDEF; YEATS4; SSBP3; ZNF43; CREBL2; VPS72; RAD21; IFI16; PNRC1; MKL2; EMX2; POU2AF1; ID1; HHEX; IRF9; SOHLH2; ZBTB20; INSM1; ST18; ZHX2; FOXE1; CALR; MYBL1; ZEB1; PBX3; TP63; HOXB2; NFATC4; MNDA; TRPS1; TLE4; WT1; OSR2; HES1; GATA6; NFATC3