Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63262	Ropinirole	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	185	XBP1; BCL10; MED7; C1D; MTF1; FOXJ3; RNF6; REST; TRIM22; NR2F2; GTF2IRD1; NUP62; ZBTB1; BAZ1B; FHL2; HDAC6; USP22; RNF111; HMGA2; UBP1; ZNF783; SIX1; TSC22D3; MTDH; MED4; SFPQ; ADNP; BIRC2; ARID4A; MED13; ZFP64; TBL1X; RAN; SP100; ZBTB11; ZNF217; ERG; ANKRD1; SMAD2; BAZ1A; TRIM16; COPS5; LPIN2; BMI1; ZMYM2; RBM14; ATF1; SMAD7; PCGF3; BLZF1; BPTF; CBX3; MEOX1; HOXC10; HOXA10; CRK; HABP4; TEAD1; ASH2L; SMAD1; ZZZ3; TFE3; PHF8; ZNF7; ZNF468; RSF1; GTF3A; HMG20A; RNF4; RBPMS; SOX15; TAF9; MBD2; NR1I2; CBFB; BCL3; ELF1; FOXD1; CTR9; TMF1; PRRX2; ATF2; KLF5; CDK8; REPIN1; NFE2L1; CARM1; RBBP5; ZBED1; TCERG1; SMARCA4; RB1; PTRF; ENY2; CLOCK; SIX2; ATF4; ING2; SMARCA5; MEOX2; PLAGL2; KDM5D; BRD8; MDFI; NRBF2; TAF7; CREB3L1; TSG101; KLF2; CBX6; WWTR1; NFAT5; AHR; SMAD6; ASCL1; BANP; SP140L; ARNTL; CHD9; TADA3; ELF5; BCOR; HLTF; DMTF1; NFKB1; RCOR1; NFATC3; ERBB2; BASP1; PHF20; NCOR2; SIM2; HMGN3; COPS2; MECOM; DDX5; TAF1D; EGR3; ZNF146; YBX1; FLNA; UBE2B; RBBP8; MNT; MNAT1; ELK1; RUNX1; HNRNPD; MAGED1; HIF1A; BRD3; ZKSCAN1; PIAS3; DR1; SAP30; YWHAB; NR1D2; TSC22D1; SNW1; MYCBP; TSC22D2; NCOA4; TSC22D4; NFIB; TRIM29; PURA; PATZ1; SMAD3; MYC; TGFB1; PAWR; CUX1; ZMYND8; STAT6; ENO1; HDAC1; VGLL4; HOXC6; WWP1; RBPJ; HDAC2; ZBTB38; IKBKAP; TOB1; IRF8
Down-regulation	162	GTF2F1; TFAP2C; LIN28A; GATA4; DNMT1; NOC2L; PBXIP1; EN1; PFDN5; PHIP; HIC2; E4F1; PSMC3; HOXB5; ZNF43; GMNN; ZFP36L2; JUN; SMARCA1; LHX2; ZNF266; NR1I3; FLI1; ZNF232; IRF6; CD3D; TCF21; ZNF274; SSX1; RING1; PRDM14; ZNF345; ZIC3; RREB1; PNRC1; ZNF219; EN2; ZKSCAN4; FOXL2; NKX3-1; SLC2A4RG; ZNF571; ZNF85; RFXANK; SIX6; NKX3-2; HAND1; ZNF711; ZFPM2; POU2AF1; BCL11A; NFE2; THAP7; ZNF500; ZNF215; HOXC4; NFYA; NCOA1; ZNF93; ZNF74; SSBP3; ZNF136; HEY2; TCF25; RBL2; TFCP2; CALR; ZNF331; ZNF133; GFI1; HDAC4; CTNNB1; MYCN; ZNF117; TCEA2; TAL1; SIX3; CDK2; CDK9; NR4A3; HIRA; MYCL; FOXF2; VGLL1; BNC2; WNT4; PBX3; PHF1; PRDM1; PRDM2; CREG1; SRCAP; EPAS1; ZSCAN31; ZNF239; MED15; BACH2; TFDP2; SOX17; HOXB6; MNDA; IRF9; HLX; ARID1A; ZNF350; CNOT6; AR; CBX4; EMX2; SMARCB1; ESRRG; HIPK2; DLX5; MXI1; KLF1; NKX2-1; AES; TTF1; NKX2-2; SALL2; GRHL2; IRF4; NR5A2; ZNF394; OSR2; MLXIP; PAX6; NR0B1; PITX1; TBX3; ZNF91; ERBB4; FOXO3; SSBP2; MYRF; HHEX; SALL1; SOX13; DLX2; SOHLH2; CBX7; HOXB2; BTG1; LEF1; MYBL2; DAXX; SNAI2; NFATC1; TP53; MKL2; WT1; MAF; MEF2C; RAD21; ZNF423; FOXF1; JUP; MEIS2; HEY1; ATF3; ID4; ZNF589