Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63253	Methantheline	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	160	KDM5A; ECD; GATA2; TBL1X; NFIC; CHD9; ELF2; ZMIZ2; ADNP; MGA; CDK7; ZNF268; NR2F2; SP100; BRD8; TRIP6; TRIM22; MAML1; NKX3-1; ZNF304; PCBD1; TAF11; REST; MEOX1; FLNA; ZNF45; ZNF184; BIRC2; CRYM; PSPC1; RYBP; POU4F2; PIR; RBPMS; EZH2; AFF1; C1D; LPIN2; ZNF148; PEG3; SP140L; ARID4B; NFAT5; TSC22D4; BAZ1A; SMAD7; CEBPZ; ING3; ZBTB11; NFYC; TRIM33; SP3; FOXJ3; HDAC3; PSIP1; NR0B1; CITED2; KMT2A; DPF2; TBX21; CTR9; EZH1; ZZZ3; HNRNPD; PIAS3; PBXIP1; SP110; SOX10; LITAF; MECOM; STAT3; JARID2; ZNF263; HOXA5; ZNF384; ITGB3BP; MED23; SSBP2; PLAGL1; CREB3L1; ZNF112; ATF2; ZBED1; TAF1D; CNOT2; SNIP1; ZBTB38; NEDD8; TCF25; TAF7; ZNF468; HOXA11; IKBKAP; RERE; MED17; APEX1; GTF2A2; DNAJC2; FOXJ2; CNOT1; KAT2B; PTRF; CAMTA1; ZNF84; WWTR1; TLE1; NCOA4; RBBP8; ZNF329; HOXC6; HMGB2; RFX5; CBFB; SUB1; OSR2; SCMH1; KDM5D; TGFB1; PIAS1; RCOR1; RBPJ; TBPL1; ETV6; ETV5; HLF; HDAC1; NFATC3; NR2F1; BBX; PMF1; EMX2; ISL1; ELF3; RORA; SMAD1; MNAT1; TRIM28; YWHAB; ABL1; CCNE1; POU4F1; TGFB1I1; NR1H2; TGIF1; MSX1; TULP3; FOXM1; MAGED1; MNDA; ZFHX3; HDAC2; VGLL4; HOXB2; TSC22D3; IRF8; SALL1; ZBTB16; POU2AF1; HHEX; HMG20B
Down-regulation	123	TCEA2; PPRC1; TFAP2A; HIPK3; HIRA; AEBP1; ZFP36L2; ZNF43; TAF9B; LIN28A; KLF10; CDX1; E2F5; ETS2; EPAS1; GATA6; ZBED2; HMGB3; MLLT10; RXRG; CNBP; SOX3; BACH2; TFDP2; LZTS1; E2F3; CDX2; ZNF93; ZNF688; ZNF667; ZNF117; HTATIP2; FLI1; MAFF; ZNF665; RFXANK; ZNF652; NFYB; SNAI2; PRRX1; SUPT6H; SREBF1; PDLIM1; PQBP1; HLX; NAB1; GTF2I; ERG; CITED1; PRDM14; STAT2; CEBPG; NPAS2; SATB2; KMT2B; TGIF2; TDRD3; MYCN; MKL2; FOXA2; SMARCB1; ZNF302; ZSCAN18; DACH1; ZNF74; SPEN; ZNF85; BRD4; KLF11; ZNF711; NR5A2; INSM1; HIC2; TFEC; PAWR; SOHLH2; EGR3; ATF3; SOX13; FOXG1; LMCD1; TOB1; PSMC3; TRPS1; HEY2; TDP2; LEF1; MEF2C; FOSB; SOX11; CREM; MAF; MDM2; PROX1; NFATC4; ATF5; ERBB4; KLF13; NCOA2; PBX3; ID4; NR1H3; PAX6; TP53; ZNF331; ZNF91; ZFHX4; DLX2; KLF6; NFATC1; BCL3; ZNF264; ZIC1; KLF4; WT1; HDAC9; MYBL1; ZNF589; TBX2; CDK2; TBX3; ID1; EGR2