Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63251	Harpagoside	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	SMAD4; TRIM22; CEBPA; TAF1D; E2F3; HIPK1; FOXJ3; ELK3; XBP1; CTBP2; BLZF1; CHD1; MED7; BCL6; ZBTB1; ZNF24; BAZ1A; ZNF267; ELF4; STAT2; MECOM; ZNF623; TOB1; ERG; PIR; PHF20; MEF2A; RUNX1; NR2F2; ELF5; MTF2; RNF138; TSC22D3; RCOR1; CCNH; TCEA1; CLOCK; COPS2; CSDE1; TCFL5; DDX5; NUP62; SPDEF; NFE2; NAB1; CHD9; SMAD1; NFIB; ZBED4; PAXBP1; CBFB; KLF10; BIRC2; HDAC7; PRMT2; RBFOX2; SMAD2; TDP2; ZMIZ1; E2F5; TAF4B; ZNF3; PIAS3; MAFG; HMGN3; CCNC; RNF4; RUNX3; HOXD1; FUBP1; ZNF281; HIF1A; NR2C1; NR2F1; DMTF1; MNT; ZNF124; MED17; PAWR; RBPJ; VPS72; MEF2C; CITED2; TGFB1; CRK; NRBF2; SOX12; ZNF532; TSC22D4; MYC; ATF4; DAXX; RORA; ST18; HDAC2; HES1; HDAC9; THAP11; SMARCD3; YWHAB; BASP1; MYBL1; CDK2; NFATC4; ERBB2
Down-regulation	97	MED24; SFMBT1; PREB; AATF; TLX1; NKX3-1; PHOX2B; SSRP1; TFDP2; HIRA; CTCF; MED27; GATA3; PAX5; CIZ1; TCEA2; ABL1; HAND1; TCF21; SLC2A4RG; RAN; MLXIPL; EHMT2; FOXO3; CD3D; SSX1; SATB2; AEBP1; PRPF6; NELFB; TOX4; BTG1; RLF; UBTF; FOSL2; TP53; JUN; PARP1; POLR2A; POU2AF1; CNOT6; BRD2; KMT2B; GATAD2A; ETS1; PTTG1; HEY2; NFKBIA; TXNIP; CAMTA1; REXO4; MAF; MED1; WT1; PRDM10; HSBP1; PITX1; TBX3; SSBP3; PSMC3; HDAC4; DACH1; HOXB13; ZNF350; CBX4; C1QBP; ZNF93; SAP18; TCEB2; NR1H2; HLX; INSM1; BHLHE41; MEOX2; FOXL2; HOXC6; FOXF1; CBX7; CARHSP1; ZBTB38; ZNF331; ZNF264; JUP; TBX2; SALL1; BCL11A; RXRA; SCAND1; MYCL; EGR2; MSX1; OSR2; MAFB; ZBTB20; ZNF589; KDM5D; NFATC3