Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63213	Mexiletine	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	94	TRIM16; BAZ1B; PPARD; BCL6; HIPK3; ZFP64; NCOR2; TFEC; SREBF1; NFIC; FOXJ3; BMI1; BAZ2B; FOXD1; PLAGL1; ORC2; KLF5; TMF1; BHLHE41; TFEB; ZBTB38; AHR; ENO1; RBPMS; NFKB1; RBM14; NEDD8; SOX9; DPF2; MNDA; ZKSCAN7; SUB1; FHL2; MED6; BASP1; APEX1; MEIS1; BHLHE40; TCF12; TLE4; BAZ1A; SIX2; RUNX1; ELK3; TBL1X; LMCD1; MAFB; NCOA1; SNW1; ZNF189; PCGF2; SIX1; IRF8; CBFB; HSBP1; SMARCE1; DNAJC1; NONO; MAGED1; EDF1; HIVEP2; ZNF146; TRAK1; BCL3; MNAT1; TADA3; AR; CRK; TCEB2; FLNA; RXRA; PIAS3; TSC22D1; GABPB1; VGLL4; KLF4; TSC22D3; EMX2; TRIM28; ABL1; PITX1; HNRNPD; NCOA4; ERBB2; TP53; USP22; DMTF1; HDAC2; MSX1; TCF4; TSC22D2; HEY1; KDM5D; ATF5
Down-regulation	98	HSF1; PAX5; PBXIP1; HOXC5; LHX6; CD3D; BACH2; HIRA; LHX2; RREB1; FOXI1; TFAP2A; ZNF232; SOX18; NFYB; ILF2; DNMT1; ACTL6B; HIC2; NKX3-1; LEF1; HMGB2; E2F2; NR0B2; IRF3; PEX2; NCOA2; TCEA2; ZNF623; MEIS2; IRF9; ZNF573; AEBP1; MYBL2; SHOX2; YEATS4; HOXC4; E2F5; NR1H2; TERF1; ZNF711; ZNF350; WNT4; CREG1; NR4A2; TCF21; BCL11A; CHD7; MYBL1; VEZF1; SATB2; CDK2; NFE2L3; TOX; SUZ12; ATF3; ID3; SOX13; CBFA2T3; DLX2; ZFP36L2; BTG1; WWP1; ZNF107; PBX3; ZNF239; RAD21; MKL2; MXI1; ZBTB16; HHEX; CTBP2; SOX17; MEOX2; GRHL2; TBX3; TOB1; STAT1; ETS1; FOXG1; GATA6; SPIB; TP63; IKBKAP; ZHX2; TGIF1; ZFHX3; MYCL; ZNF331; ZNF589; NFATC4; INSM1; WT1; ID4; CALR; JUP; ERBB4; NFATC3