Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63210	Nimodipine	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	363	PAX8; GATA3; KDM5B; IKZF1; ZNF131; BRCA1; WDHD1; ZNF510; NUP62; PPP1R13L; HDAC6; NHLH2; BRIP1; EN2; ETV1; RCOR3; MLLT10; EGR1; SOX10; ZNF432; PGR; JAK2; NRIP1; TFAP2C; RB1; RBL1; ATF7IP; TTF2; IRF1; TXNIP; HR; XBP1; CRY1; RBPMS; LIN28A; ZNF202; ZKSCAN8; BHLHE41; PRDM13; NEUROD1; MBD4; GTF2I; IRF5; ZNF248; ZBTB25; ZSCAN18; ARID4B; TP63; BARX2; MECP2; FEV; PPARD; PITX1; ADRB2; PARP1; BAZ1A; KMT2A; STAT5B; ZNF257; ZNF160; ZNF274; ZNF226; ZNF492; ZNF273; MXD1; ZNF141; ZNF460; TRIM33; EHMT1; WNT4; ZFP69B; HNF1B; SMARCA2; PHIP; ZIC3; INSM1; CBX8; DMTF1; BMI1; TOX; ZNF711; GABPA; KLF3; TAF9B; NFRKB; BCOR; SOX4; ZNF721; ZNF468; TLE4; MDM2; IKZF5; POU5F1B; SOX30; SP140; AGO2; PKNOX1; ATF6; AFF4; BRWD1; ZNF80; GLI2; MAPK8IP1; ZNF493; EGR3; ZNF480; MTF1; ZNF227; AFF3; HMGN3; BANP; ZNF675; ZFY; ST18; PHOX2B; ZNF639; BHLHE40; BIRC2; BACH1; TBR1; SHOX2; BATF; TRIM29; PRKDC; ANKRD1; RUNX2; SP1; LHX2; E2F1; HLF; PHF8; FLI1; ZNF329; BAZ1B; ASCL1; ZKSCAN7; ZNF157; ZNF611; EHF; FOXN1; SIN3B; ZNF528; SMARCA4; NR2F6; DNMT3B; HIVEP2; HMGA1; RAN; ZNF165; RBBP8; ZNF682; ZNF814; CAPN15; RORA; ZNF695; ZNF236; ZNF613; CEBPA; FOSB; POU1F1; ZBTB14; KDM5D; ZNF107; FHL2; NACA2; ZNF41; MYT1L; RFX7; FOXL2; ZNF440; TBL1XR1; KMT2D; ZMYND11; POU2F3; SATB1; PCBD1; PRMT2; SP140L; FOXN3; HSF2; ID2; SFMBT1; GFI1B; PEG3; IL16; MGA; HTATIP2; ELF5; ATF7; CDIP1; IRX5; MNX1; CREBZF; RFXAP; ZNF217; ZNF426; ZNF133; WHSC1; ZNF45; BNC1; MEOX1; STAT5A; CHD1; FOSL1; ZBTB44; DOT1L; OVOL2; KLF4; MXD4; HCFC2; HIPK3; NR3C1; LYL1; ZNF253; DDX17; FOXD1; LHX3; PSMC3IP; ARNT; TAF4B; DNAJC1; RBBP4; KDM4C; RBL2; DBP; TAF1A; NPAT; PML; ZNF10; HDAC3; ZNF614; ZNF225; NKX2-1; HOXC13; PAX6; TAF1; ZHX3; WHSC1L1; KDM4A; TFDP2; CTBP1; SSBP2; AFF1; HLTF; ARRB1; BCL11B; HMGB3; ING2; MNDA; ACTL6A; RNF111; NCOA3; ATF1; MZF1; ZNF93; EBF2; IRF4; MEOX2; TRIM25; DDX5; IKZF2; ZNF701; HOXC6; ZNF665; SUV39H1; ENO1; GLI3; NR4A2; PRDM1; ZNF816; ZMYM2; YAP1; FOXG1; TSC22D1; TSC22D2; ZNF337; CBX6; ARNTL2; ZNF143; RNF14; TAF7; MYCN; HOXC4; SOX3; ISL1; SPDEF; MAFG; SOX13; NCOA2; ELK4; NR0B2; TFEB; ELF3; ARID3B; PURA; NR1H4; ZNF264; PEX14; MDM4; MLX; FOXE1; HOXC10; ZNF410; TSC22D3; REL; PLAG1; BTF3; IFI16; TRRAP; PQBP1; ETV6; NR2C1; TWIST1; BNC2; SSX1; YEATS4; PCGF2; HOXB13; ADNP2; FOXC1; FUBP1; CHD9; KLF11; ZMIZ1; UBP1; NEDD8; YBX1; GRHL2; ZNF654; HOXB2; ZBTB20; SALL1; PRDM2; EGR4; TRPS1; TEAD3; CCNC; HIF1A; JUND; RHOA; POU4F1; TOB1; BCL3; WWTR1; MAFB; HDAC1; CBFA2T3; ZMYND8; MKL2; IRF8; MYBL1; NR1D2; ZIC1; EDF1; CREB3L1; ZEB2; TBX2; EYA2; OSR2; NFATC3; ESR1; ID4; EGR2
Down-regulation	350	NFE2L1; KAT8; THAP4; CTCF; PA2G4; PBX1; SP100; HOXB5; GTF2F1; BRD2; TCF25; MAZ; PRPF6; PFDN5; ABT1; RING1; KLF10; SRCAP; CHD4; MMS19; YBX3; PPRC1; THRAP3; HMGXB3; MED13; NFKBIA; PDLIM1; SIRT2; SUPT4H1; SREBF2; ZEB1; TRIM16; USP16; SMARCA1; RNF10; COPS2; DNAJC2; TFAP2A; CREB3; PTRF; PCGF1; CREG1; TCF7L2; AATF; MTA1; ZNF12; TULP3; ID3; SLC2A4RG; RNF6; ZNF668; CBX4; CXXC1; SUMO1; ZNF444; SAFB; RYBP; MXI1; CCDC59; BRD4; KLF7; BPTF; KAT6B; ZNF688; CBFB; LDB1; TSHZ2; ABL1; SREBF1; HMGB1; CALCOCO1; TDP2; HOXA3; CNOT2; PSMD9; CREB3L2; VGLL4; PLAGL2; NFIL3; ERF; CBX5; ZNF512B; RFXANK; GMEB2; JUN; MAFF; NR2F2; TCF3; TBP; HIF3A; HDAC5; ARL2BP; SOX11; FOS; RUVBL2; STAT6; PRDM12; RARG; CIR1; CDK2; RARA; TFCP2; EED; ZNF423; ZNF91; GTF2A2; ZKSCAN4; SNAI2; PREB; BTG1; EHMT2; SMARCB1; MED12; CDX1; E2F5; ID1; WDR77; ENY2; MED15; ZSCAN32; DEK; ZNF768; ERCC3; HEY1; RELA; C1D; LOXL2; FOXO3; URI1; ZNF232; MED25; RBM39; CALR; REXO4; HOXB1; TTF1; MED17; MAML1; GCFC2; ZNF335; TBX10; CDX2; ZNF394; TERF2; ZBED1; MITF; SUB1; UBTF; CBX3; ZNF771; HIC2; KAT5; CENPB; TAF12; CERS6; RRN3; TCF4; MECOM; STAT1; ZNF770; CERS4; COPS5; AEBP1; THRA; KDM5C; TCEA1; ETV4; SMARCD3; GATA6; MYF6; ZNF35; TP53; INSR; HABP4; TRIM27; ZNF222; XRCC6; PMF1; ZFP30; ZKSCAN1; TCF12; ZNF263; MYCBP; GTF3A; ZNF532; SAP30; NR2F1; ZFP64; EPAS1; KLF5; IRF6; ATN1; HOXB6; SMAD3; SOX18; ZNF112; EN1; GMNN; KMT2B; RBBP5; PBX2; MYOD1; HEY2; ZNF302; SETD3; HIRA; ZNF24; SOX9; ZNF580; FOXO1; TBPL1; CEBPD; PMS1; FOXJ2; NFATC4; CNBP; CEBPG; ZNF606; BRF2; TGFB1I1; CIC; SAP18; SMARCC2; TFAM; ZNF573; IRF9; ING1; TAF11; MXD3; PSIP1; MYOG; SND1; ZNF148; FOXF2; SAP130; CNOT3; SPI1; CRTC1; KLF13; AES; PHF20; EZH2; TGIF1; CSDE1; PSMC3; SP110; KLF9; NAB1; JUNB; TADA3; VPS72; CNOT6; CARM1; ECD; HDGF; TGFB1; ELF1; TLE2; RBFOX2; RXRG; ZFP36L2; TRIP11; MNAT1; ZFHX3; ARNTL; POU2AF1; RXRB; ITGB3BP; HMG20B; TBX3; ATF4; PTTG1; PBXIP1; ZBTB17; IKBKAP; SMAD6; SMARCA5; MED6; TOX3; ZNF345; PKNOX2; RNF4; ESRRA; VGLL1; ZNF646; ZNF189; HOXD3; SMARCC1; SCAND1; HOXA11; ZNF22; PIR; USP21; ZNF593; RNF141; MED21; ZBTB7A; ZNF576; CDC5L; SPEN; MBD2; APEX1; ZFX; THAP7; MEF2C; EMX2; DR1; VEZF1; HNRNPD; SIX3; ZNF467; THAP10; NFATC1; ATF3; ALX1; ZNF430; RREB1; NR5A2; ZNF281; ZNF589; SMAD1; FOXF1; FOXJ1; TRIP4; MED1; WWP1; FLNA; PROX1; NR0B1; MEIS2; MSX1; ZFHX4; SOX17; MTF2; MYRF; ZFP36L1; ERBB4; SPIB; ETS1; NFE2L3; GABPB1; ETV5; CDK9; CCNE1; HOXA10; ARID1A; ZBTB16; WT1; MAGED1; BASP1