Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63184	Eplerenone	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	236	XBP1; ZNF217; REST; BMI1; TRIM22; TRIP6; ZBTB11; MED4; RNF6; ARID4A; NUP62; FOXJ3; MED7; C1D; BAZ1A; BAZ1B; AFF1; ZBTB18; CRY1; IRF2; TSC22D3; EGR3; BCL10; HDAC6; KLF2; ZFP64; TRIM16; LPIN2; ZNF304; CTR9; CBX3; NFAT5; PPARGC1A; PHF8; ELF2; ING2; STAT1; TAF1D; TEAD1; ZBTB1; BATF3; ZMYM2; SMARCA5; ZNF267; UBP1; ATF7IP; FHL2; ZNF468; ADNP; ELK3; SMARCA2; ATF1; GTF2IRD1; RBM14; USP22; KAT7; ZMIZ2; PLAGL2; ELF5; SMAD2; ZNF432; BIRC2; BCLAF1; ELK1; CHD1; NR2F2; TLE1; RB1; SPEN; SMAD4; SIM1; MLLT10; PSPC1; HOXC6; ARNT; HIPK1; PCBD1; MAGED1; RBPMS; SIX1; NFE2L1; PRRX1; TMF1; ZNF131; PMS1; HSF2; KDM4A; DNMT3B; REPIN1; SMARCA4; JARID2; MTDH; SETD2; HMG20A; POU3F1; SUV39H1; BACH1; MDM2; MED1; ELF1; PLAGL1; GTF3A; BLZF1; KLF10; NR1I2; PITX2; ZSCAN12; CIITA; YAP1; ZZZ3; NFIB; HOXC10; TSC22D4; FOXN3; ZEB2; ZBTB24; UBE2B; CDK8; POU5F1B; ZBED1; BRPF1; STAT5A; YWHAB; ATF2; ZNF587; MAX; MED23; PIR; PSIP1; RUNX1; SAP30; BCOR; MSX1; ARID4B; EZH2; ERBB2; ZNF146; HCFC2; SUB1; BRD3; RCOR1; NFKB1; NRIP1; BBX; MSC; RNF10; EDF1; KLF5; PHF20; FOXD1; WWTR1; STAT6; TOPORS; BAZ2B; PKNOX1; NCOR2; NFATC3; ZNF329; NCOA4; ELF3; PBRM1; MEOX2; SFPQ; CREB5; ZNF23; SAP18; MYOD1; MYC; BHLHE40; DPF2; ENO1; RBBP8; CREB3L1; HNRNPD; STAT3; BASP1; SNIP1; RFX5; SNW1; ZNF84; TBL1X; AHR; NFYC; ZNF574; ALX1; PIAS3; HTATIP2; SMAD7; TXNIP; HIF1A; POU4F1; HSBP1; TOX3; ZFX; SATB2; ATF4; TSC22D2; ZBTB38; ZNF226; CITED2; FOSB; WWP1; HOXB7; NRBF2; SP110; TAF10; PCGF2; YBX1; SMAD1; IKBKAP; BCL3; FLNA; KDM5D; IRF8; KDM2A; DNAJC1; SERTAD2; ZNF443; SMAD3; HDAC1; FOXO1; TRIM28; ZNF107; NR1D2; MAFB; SMARCD3; NFE2L3; HOXA10; TRIM29; EGR2; ZBTB20; ETV5; TOB1; FOXO4; ZIC1; PPARG
Down-regulation	237	GTF2F1; ZNF232; SOX21; DNMT1; TDP2; HSF1; CD3D; RFXANK; HIRA; ZNF544; ZNF467; LIN28A; RING1; E4F1; ATOH1; LHX3; TFAP2A; CTCF; KLF15; MXI1; NKX3-2; TP73; NPM1; HIPK2; PSMC3; FOXA2; ABT1; RUVBL1; ZNF665; ZNF91; ZNF219; PRDM14; ZKSCAN4; TEF; PGR; ZNF611; PHIP; IRF6; ZNF444; NEUROD2; FEZF2; REL; POLR3C; VGLL4; TFDP2; ZNF688; ZNF354A; EN1; POU2AF1; SMARCB1; EPAS1; CBX2; LZTR1; ZNF273; SUPT3H; STAT4; ZNF215; HDGF; BNC2; SSBP3; INSR; MYCN; CDIP1; PRDM12; HMGB3; BCL11A; TAL1; BNC1; ZNF394; FOXF2; PROP1; CDX1; GATA1; RARG; ZFP36L2; MTA2; SOX11; CTNNB1; ZNF44; SIX3; BTF3; ZNF430; ARID3B; SRY; TCEA2; PRDM10; YEATS2; LYL1; ZIC3; SOX3; MEIS2; CBX6; ZNF195; THRB; TRIB3; CUX2; ZNF43; AR; GMNN; ZNF500; ZNF33B; HOXD10; MXD3; ZNF345; SOX18; ZSCAN9; ILF2; ZNF74; PFDN5; TAF9B; BARX1; GFI1; ZKSCAN1; NFE2; TBX1; ZNF85; TCF7L2; GRHL2; SOX13; NFYA; AIP; TCF7; WT1; CNOT6; NEUROD1; ZNF239; EHMT2; BRD7; KLF9; ACTL6B; CBFA2T3; SALL2; KLF13; ZNF235; TGIF2; KLF1; HOXD11; ERBB4; PRDM1; ZNF331; NEUROD6; ATN1; RBM39; ZNF557; HIC2; CBX4; ZNF117; CEBPG; MYB; FOXF1; TAF5; MNDA; HOXD3; NR5A2; BRD4; AEBP1; TTF1; FOXJ1; HLX; ZNF224; SPDEF; CREM; HMGB1; ZNF652; ID1; HOXA11; FLI1; FOXE1; SIRT7; CSDC2; SOX17; ZNF423; ZNF93; NR1H2; VGLL1; TBX3; GFI1B; AES; SPIB; ZNF22; HDAC4; HEY1; ESRRG; WNT4; PBX1; ZNF415; ID4; CDK2; PCGF1; TRIM27; MEIS1; MKL2; ARID1A; FOXG1; TCF21; TOX; ZHX2; THAP7; PITX1; ZFHX3; ST18; NFATC4; TRPS1; IFI16; FOXM1; PAX6; HOXB13; ZFPM2; MYBL2; ZNF136; IRF9; TCEB2; ETS1; CNOT3; NAB2; ESR1; MYBL1; ZNF264; FOXK2; SOX9; GATA6; CDK9; VPS72; ZNF589; CRK; MYRF; BTG1; SSBP2; CUX1; MLXIP; ATF3; SALL1; HDAC9; CALR; HHEX; TCF4; OSR2