Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63161	Securinine	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	HDAC6; PCGF3; FOXD1; NFIC; TBPL1; HABP4; MXD4; GTF3A; EMX2; HMBOX1; GABPA; TEAD1; NFIX; ZMYM2; JARID2; TRIM16; BACH1; SETD2; EP300; HOXC10; NFIB; KLF5; TAF9B; NFATC3; SOX4; KLF6; NFYC; RBM14; HOXA1; MXD1; FOSL1; PCGF2; AHR; CHD1; MED6; GTF2I; BMI1; SNIP1; ZNF226; SMAD2; SMAD3; EDF1; RNF141; KLF2; ZBTB1; PIAS1; ZMYND8; MAFG; KLF7; RERE; BHLHE41; RBBP4; NCOR2; ZBTB43; ZNF576; FLNA; SERTAD2; DMTF1; MAFB; TAF10; MEF2C; TRIM25; NEDD8; NUP62; SMAD6; PIR; TWIST1; ID2; RNF4; SIX2; MTA1; PQBP1; DNAJC1; ENO1; YWHAB; SIX1; KLF11; FOXC1; SMARCE1; MNAT1; HDAC1; PSIP1; TSG101; NONO; AR; TP53; TCEB2; RBPJ; ELF3; HOXC6; GABPB1; RORA; IRF8; RXRA; ZNF281; ZEB2; CITED2; KDM5D
Down-regulation	162	HSF1; DACH1; PEG3; ZNF232; PLAGL1; KAT8; CDX1; CEBPG; SMARCA1; RUVBL1; DNMT1; ZNF354A; TCF21; MEIS2; CITED1; TCF20; GLI2; ATOH1; MAZ; SIN3B; PBX1; HIC2; CREB1; ZNF665; ZNF22; MED25; ZNF43; ZNF345; NFE2L3; RAD21; NCOA2; ZKSCAN4; ZSCAN18; PAX5; LIN28A; CDX2; ZNF85; SALL2; THAP11; YBX2; CBX5; HIRA; HOXD1; CD3D; SUZ12; ZEB1; MED13; FOXF1; CBX4; BACH2; PFDN5; ZNF467; PITX1; ZNF331; BCL11A; DEK; CREB3L2; SSX1; SRCAP; ZNF140; CRYM; RXRB; SIX3; USP21; BAZ2A; FOXF2; MYB; REPIN1; TRIM22; CALR; COPS5; ZNF426; CREG1; TDP2; TERF1; TDRD3; ZNF215; TGS1; TGIF1; CTBP2; SPI1; TBX3; CBFA2T2; UBP1; CLOCK; HMGB2; PRDM2; ZNF623; CNOT3; ZFP36L2; FLI1; TULP3; POU2AF1; ZNF93; YAP1; BNC2; AES; EYA1; IRF6; KAT6B; MAFF; ZNF302; NR3C2; IFI16; SMARCC2; CRK; ZNF12; E2F5; TCF7L1; CDK2; TGFB1I1; THRA; TFEC; EPAS1; TOX; MKL2; MYBL1; HEY1; GRHL2; ZNF146; SOX13; ERBB4; CERS6; PBX2; ABL1; WWP1; ZNF239; INSM1; PNRC1; SOX17; MXI1; KDM5C; STAT6; ITGB3BP; ZNF423; ZHX2; LEF1; SHOX2; ZNF117; ATN1; SSBP2; ACTL6A; HOXB2; PAX6; ZNF91; WWTR1; TGFB1; ZNF589; TCF4; FOXG1; ID4; ETS1; ID1; VPS72; AEBP1; NFATC4; GATA6; TLE4; BASP1; FOXO4; ZMIZ1; PBX3