Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63148	Alfuzosin	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	150	XBP1; CEBPA; NFIX; FOXJ3; ERG; BAZ1A; NFIB; RBBP5; KLF5; ASCL1; CTR9; ZBTB11; ZNF226; TCERG1; TRIM16; MED7; HDAC6; SMAD2; AHR; LPIN2; TAF1D; IRX4; NUP62; ZNF131; TSC22D3; CBFB; ZSCAN12; ARNTL; ZHX3; TSC22D1; C1D; TRIP6; SMAD1; NCOR2; ZMYM2; BAZ1B; PKNOX1; MEIS1; TOPORS; BIRC2; PCBD1; UBP1; BCLAF1; NR2F2; BCL6; SMAD5; SETD2; MXD4; DNAJC2; BHLHE41; ING2; CRK; DDX5; ZNF143; BANP; TOB1; ZNF576; NKX2-2; BATF3; CREB3; RBBP7; YWHAB; OLIG2; TMF1; NKRF; SETD3; ZZZ3; PSPC1; GTF3A; ATF7IP; ZBTB18; MECOM; ELF5; PURA; DR1; FHL2; NCOA6; EGR3; KDM5D; RBPMS; RUNX1; BMI1; NFATC3; CBX6; MED23; ZNF468; COPS5; TULP4; SF1; MTDH; BRD8; ELF4; IRF8; ZBTB38; YEATS2; PIAS2; PSMD9; ZNF587; FOXC1; ZNF23; HSF2; ELK1; ZNF532; BCL11B; BRD4; EGR4; EHF; CREB3L1; HCFC2; MAGED1; ZKSCAN1; MEF2C; PHF20; MED13; FOSB; FLNA; RUNX3; HTATIP2; SOX9; SMARCA2; NFKB1; PIR; MAFG; HOXB13; MEOX2; RCOR1; ZNF281; NR1D2; MYC; ERBB2; HMGN3; NCOA4; SIX1; PSIP1; SIM2; BCL3; HEY1; ZFHX4; BASP1; TRIM28; CUX1; NRBF2; MED1; ETV5; HOXC6; TAF10; ZBTB16; HDAC2; RBPJ; EYA2
Down-regulation	160	TRIB3; ZNF232; GTF2F1; LIN28A; HSF1; PFDN5; CREB3L2; RREB1; ABT1; ZNF154; TCF3; POU2AF1; MNX1; SSX1; PRDM14; SALL2; HIRA; ZIC3; THRAP3; CD3D; EHMT2; ZNF93; AIRE; ZNF43; SUPT3H; ARID3A; HSF4; HIC2; BNC2; PCGF3; CDX1; SMARCD1; ATOH1; HDAC4; ZXDC; ZKSCAN4; ZNF711; NKX3-2; SLC2A4RG; BACH2; BTG1; AES; PBXIP1; ZFP36L2; NANOG; SRCAP; TCF7L2; PHF1; ZBED2; KAT5; ZNF215; PHIP; GFI1; TFAP4; FLI1; CALCOCO1; IRF5; SSBP3; SMARCA1; KDM5C; EN1; SMARCB1; HMGA1; HMG20B; ZNF695; MXI1; STAT4; SIX3; UBTF; MAZ; ZNF250; CTNNB1; KLF11; ZNF85; ZNF91; ZNF354A; PRDM1; TFCP2; NEUROD1; EMX2; MED16; CBX4; TCEA2; ZNF345; TOX4; GATA1; PRPF6; SOX13; PIAS4; CRYM; VEZF1; TFAP2C; TGIF1; ZNF665; ZNF117; PSMC3; ZNF107; IRF6; MLX; HMGB1; NR5A2; KLF10; ID3; TCEA1; ZNF22; ZNF253; DACH1; ERBB4; ZNF74; E2F8; TFDP2; ID1; CALR; PBX3; PRDM2; HOXB2; NFE2; ZNF136; JUP; E2F5; IRF4; HOXD3; FOXO1; AR; KLF1; HEY2; MNDA; RXRA; CARHSP1; TDP2; MYBL2; ARID1A; CNOT3; CBX7; BCL11A; IRF9; DDIT3; TERF1; CHD7; ZNF331; NFE2L3; OSR2; NCOA2; MEIS2; ATN1; PBX1; TRPS1; STAT1; MKL2; RAD21; SALL1; MYRF; TCF7L1; ZNF589; DAXX; NFATC4; DLX2; HHEX; TBX3; ID4