Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63136	Chlorphenamine	GSE92742	SKB	Human	24h	10uM	EID0353

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	XBP1; RB1; TRIM22; GTF2I; UBE2B; EPAS1; IKZF5; HIPK1; TEAD4; INSR; C1D; HMGN3; MEF2A; TAF9B; AFF1; DDIT3; ZZZ3; MYF6; TFCP2; GTF3A; RERE; TFE3; AGO2; BHLHE41; PAX5; SAP30; KLF2; TRAK1; NFIB; SETD2; BRD8; HOXA5; FOXJ3; SOX11; RUNX1; ZSCAN31; TAF9; TFAP2C; CBX3; ELF1; MEF2C; SMARCD3; PIR; ID2; NKX2-2; SIX2; ECD; NR2F1; MNAT1; LYL1; FUBP1; ZBED1; MAGED1; DDX5; TXNIP; MYC; WWC1; PIAS1; TSC22D3; ZNF165; NFE2; HTATIP2; DMTF1; DAXX; THAP10; POU4F1; TGFB1; ATF4; MECOM; MED6; EMX2; TAF12; HDAC1; SOX9; MEIS1; HHEX; AHR; MED17; STAT6; NR0B1; TCF12; ZNF410; NKX2-1; NR1D2; ZBTB18; NCOA4; FOXE1; ZHX2; ZMYND8; HMGB2; IRF9; IKBKAP; MYRF; SMAD3; POU2AF1; GABPB1; ST18; ETV5; SERTAD2; FOSB; ARID5B; HOXC6; VGLL4; ERBB2; ATF5
Down-regulation	137	ZNF512B; SATB2; MXI1; LIN28A; PLAGL1; BRD7; CD3D; NKX3-1; TRIP6; TOX; XRCC6; TCEA2; ZIC3; ENO1; CREB3L2; PITX1; ZNF345; ZEB1; ZNF586; MBD2; ZNF652; ZNF44; ZNF232; SSRP1; TAF5; ARL2BP; TFDP2; ZNF184; C1QBP; FOXF1; PBX2; HDGF; LITAF; DACH1; ETS1; CREB5; JAK2; CDX1; MAFB; LMCD1; NR1I2; UBE3A; PRDM14; SALL2; HMGB3; RBPMS; PA2G4; ZNF224; IRF6; BNC2; RLF; SNAI2; CNOT2; MAF; ZNF426; RAN; NCOA3; KMT2B; DDX17; PHF1; ZNF91; NANOG; SREBF1; KLF5; ZNF264; ZNF3; TCF7L2; ZNF22; SSBP3; ZBTB20; TDP2; ZIC1; ZFHX4; RXRB; ERBB4; HDAC4; ZBTB7A; NFE2L3; MITF; EYA2; TCF21; FOXL2; ZNF180; ZNF124; SP140L; TP53; RUNX3; ABL1; KLF11; NCOA1; MYCL; EHF; IRF4; KLF4; NCOA2; CCNE1; ZNF654; KLF13; USP21; SUZ12; SMAD7; ZNF93; HOXB7; HOXB13; FOXG1; TRPS1; TBX3; MSX1; CARM1; ID1; JUN; PKNOX2; SMAD1; MEOX2; SPIB; BTG1; HIF1A; BCL3; ZNF589; CBX7; SAP18; CARHSP1; FLNA; TRIM29; SCAND1; CRK; NFATC1; TLE4; TBX2; ZNF331; NFATC4; WWTR1; TOX3; BCL11A; NFATC3; WT1; FOXO4