Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63118	Betahistine	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	FOXJ3; XRCC6; ZNF512B; UBE2I; DDX17; CREB3L2; KLF1; PTRF; OSR2; FOXL2; CREG1; CNOT2; WDR77; TGFB1I1; CREB3; GFI1B; LITAF; CSDE1; ZFHX3; MITF; HDAC1; MED15; IRF9; SMARCA2; GTF3A; ID4; EGR2; ATF4; BAZ2B; NCOA3; SOX9; PSMC3; ZNF667; ZNF652; YWHAB; ZNF131; ATF6; ZNF175; ELF5; NKX2-1; SNAI1; NFX1; TAL1; ZFP36L2; STAT1; ZNF93; GMNN; MYBL1; CBFB; ZBED2; HIRA; MYCL; ESRRG; VGLL4; ZNF91; SUB1; FOXC1; ARID5B; MKL2; MEOX2; SALL1; NAB2; MAF; RARA; JUP; SIAH2; TFEB; RBBP7; HLF; MXI1; MAFF; IRF7; SSBP2; APEX1; TCF7L2; ENO1; CDK2; GATA2; ZMYND8; NFIB; PHIP; IFI16; PBX1; AHR; LMCD1; TOB1; ZSCAN18; HOXA11; HES1; NR2F2; PAXBP1; SMAD3; HDGF; NFIC; SHOX2; TRIM24; CEBPD; TRPS1; PIR; SIX2; RAN; CEBPB; NR2F1; FLNA; SCAND1; PBX3; ID2; ZBTB16; ATF3; ZFP36L1; TCEA2; POU2AF1
Down-regulation	103	CCNH; PTTG1; CEBPG; PAX6; USP22; TFAM; EZH2; URI1; MAML1; GTF2A2; ASXL1; ZNF506; MED7; CCNA2; ZNF529; SMARCA5; HAND1; HDAC4; ZNF146; ESRRA; EN2; CNOT6; HIF1A; ING2; NEDD8; ENY2; ELF3; DNAJC2; SAFB2; PEG3; ZNF302; KLF4; KDM2A; BATF3; BCL11B; DR1; ZNF536; NFYA; NPM1; ZNF22; NRBF2; MYT1L; HOXB7; PURA; ZMIZ2; BIRC2; SIM2; EGR3; MED1; MAGED1; MEIS1; MYCBP; BAZ1A; PIAS2; TCERG1; ZNF189; MYB; RFX5; E2F5; BRD8; E2F2; ZNF23; RNF14; INSM1; TAF7; TRIM28; TDP2; HOXB6; NFAT5; ST18; MYRF; MAX; NCOA4; SAP30; KLF5; PITX1; ITGB3BP; HOXB2; RCOR1; FOSB; KLF2; KDM5D; ISL1; HOXC6; TERF2; TWIST1; ZBTB18; SATB2; MTF2; CD3D; NR0B1; TGFB1; BTG1; TOX3; SIX1; BASP1; NEUROD1; TXNIP; WT1; RELB; ZIC1; ID1; LEF1