Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63114	Pyrimethamine	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	ZNF586; IRX5; ADRB2; ZNF419; FOXJ3; TCF7L1; STAT2; ARNTL; ZNF587; RBM39; ASXL1; NKX2-1; PAX5; MNAT1; HOXA1; CCNT1; ZNF131; PBX3; IRF4; TLX1; NR2C1; OSR2; RCOR3; PAWR; MED16; ASCL1; INSR; ZNF84; CBFA2T3; ZNF551; ZSCAN18; HMGB3; IRF5; GMNN; ATF4; HMBOX1; HMGA1; LPIN2; ZNF415; CDK8; LMCD1; GFI1B; PSPC1; NFX1; MBD1; DDIT3; IRF7; ZBTB16; ATF6; YAP1; TBX3; SMAD6; SMAD2; RAN; NR0B2; SNAI1; CCNC; ZNF331; KLF2; FOXC1; IRX4; SMAD3; PHF20; YAF2; FHL5; TOB1; MAF; ZEB1; RORA; NR4A2; DNMT3B; RXRA; STAT1; ZNF516; BLM; PIR; ENO1; TGIF2; HES1; SERTAD2; RUNX3; IL16; NFIB; TRIM22; ZNF652; NR1H2; PBX1; ILF2; MNDA; SOX10; NR0B1; AGO2; ERG; ZNF423; CHD7; CEBPD; KLF11; BCL11A; HMGN3; MYBL1; MAGED1; ZNF589; MEIS1; PSIP1; IRF6; BTG1; SIX1; CEBPB; GATA2; SOX11; FOSB; BASP1
Down-regulation	131	MYC; IKBKAP; ZBTB14; TFAM; NLK; MYCBP; EHF; ZBED4; PCGF1; RBFOX2; ETV5; UBP1; BBX; LZTS1; SOX9; MED21; EZH2; HDAC1; HDAC7; TAF1; BCL6; ZBTB38; MED7; POU4F1; EED; STAT5A; DAXX; NELFB; SMARCB1; PHF2; ZNF148; NFAT5; POLR2A; CHD8; FOXL2; NRIP1; TSC22D1; ING2; PKNOX1; SNIP1; ZKSCAN7; VEZF1; HLTF; ZNF14; HOXB7; NR1H4; MYB; CSDE1; CBX7; ZNF12; BHLHE41; RBBP7; OVOL2; UBE3A; NR3C2; PAX8; CHD4; MYRF; HMG20B; BAZ1B; PAX6; ZNF468; NEUROD1; HOXB6; GTF2A2; EDF1; MED1; NKX3-1; EGR2; FOXF1; ZMYND11; TBL1XR1; WWC1; BCL3; ZEB2; JUNB; BMI1; HMGXB4; SMARCA4; MAX; TGIF1; ELK3; URI1; NPAS2; ZNF22; MLLT10; TLE4; PITX1; EGR3; STAT6; TOPORS; IFI16; EYA1; REST; ZNF226; CARHSP1; EYA2; SATB2; SP3; CCNA2; SIAH2; MITF; GTF2IRD1; THAP1; TERF2; HDAC9; ELF1; HMGB1; HIPK3; HOXB2; ST18; HOXC6; PPARGC1A; ABL1; JUND; YBX3; NAB1; TXNIP; MLXIP; SATB1; RCOR1; ERBB2; HLF; KLF9; BRD4; PEG3; DACH1; NR3C1; LEF1; KDM5D; ZIC1