Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63107	Sertraline	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	142	SALL2; E2F3; TFAP2C; HOXC13; ZFP36L2; PLAG1; HOXC11; TRPS1; SOX2; ZBTB44; TULP3; ARID5B; PRDM14; RUNX1; NFRKB; ARNTL; KLF5; CENPF; ING4; GATA1; TCF3; TRIM29; FOXC1; FOXO3; ZNF239; SMARCD3; GFI1B; TCFL5; ZNF232; BHLHE40; NAB2; ERBB4; MKL2; FOXF2; TAF9B; HOXC10; ID4; FUBP1; ARID3B; MYCL; GRHL2; SOX9; TOB1; ZNF93; GATA3; GATAD2A; ZMIZ1; NCOA2; TCF7L2; NR4A2; DEK; PRMT2; TCF7L1; CREB1; CBFA2T3; YAP1; LOXL2; ACTL6A; SSRP1; ZMYND11; HIC2; FOXM1; MYBL2; HMGA1; HMGB3; HIVEP2; MYBL1; RBBP8; PFDN5; PBX3; ZSCAN32; BRD8; HMGB2; NFATC4; SMAD6; CBFB; TOX; PHF20; VPS72; USP21; NFX1; NFE2; FOXO1; NPAT; ELF4; RAD21; PBXIP1; ZNF331; HOXC6; JUP; ZNF589; KLF10; ZNF266; RXRA; RING1; EZH1; PHIP; SIM2; SPDEF; NCOA3; CREM; VDR; STAT1; HOXC4; LHX3; RFXANK; MEN1; NFIB; ZSCAN18; PBX1; ZNF217; IRF9; NR2F2; HDGF; TBX3; LITAF; CREB3L2; SMAD1; CDK2; HOXA11; ZFP36L1; LEF1; MEOX2; ZBTB16; MYB; IRF6; RCOR1; ID1; ERBB2; ID3; CEBPD; TXNIP; ELF5; NR2F1; DLX2; TAL1; TERF2; MEIS2; AEBP1; EGR3; DNMT1; BASP1
Down-regulation	87	NFKBIA; IKBKAP; NR1I2; HAND1; CAMTA1; USP22; BBX; TLE1; KMT2B; SMARCA2; ZNF148; ZNF189; NFE2L1; EMX2; ZNF536; ZEB2; USF2; PQBP1; NR1H4; ZNF146; GATA4; MYT1L; TCEB2; ANKRD1; ZNF423; PIAS1; ZBTB38; TRIM28; MTDH; NKX3-1; BMI1; HLF; ZNF22; ZNF587; ZNF329; AES; NFAT5; ZBTB18; CREB5; ZNF302; FOSL1; MXI1; MED24; TAF9; XBP1; BIRC2; SALL1; GFI1; CARHSP1; SCAND1; TFEC; COPS2; ZNF551; ZNF468; TBPL1; SFMBT1; CNOT3; HEY1; MYCN; EDF1; TSC22D1; DNAJC1; ST18; MAZ; SPEN; KAT2B; ZNF721; SIAH2; ARNTL2; MNDA; RBBP7; HMGN3; AFF1; YBX3; RUVBL2; BCL3; KLF2; EYA2; ZFPM2; SATB2; NCOA4; ZMYM2; ZNF160; MSX1; HES1; TRIM16; WT1