Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63069	Prazosin	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	IKZF1; TRRAP; HBP1; TSG101; BCL11A; TP53; ZKSCAN1; PLAG1; GATA3; IRF8; PTTG1; FOXO3; SIX2; MED20; RBL2; ZNF783; HLX; NCOA3; TRIM22; HEY1; ZNF264; TRIP6; TDP2; WIZ; TAF10; VPS72; FOXD1; ASCL1; SSBP3; ID4; PDLIM1; YBX2; ZBTB38; HMG20A; SOX13; KDM5D; ATF1; GFI1B; TLE2; TGIF1; APEX1; HTATIP2; ZNF22; STAT5B; HDAC6; SLC2A4RG; KLF2; AR; KLF5; EZH2; SIAH2; FOXO1; TBX2; HDAC2; MYB; MEOX2; CHD9; STAT1; SPDEF; ERBB4; INSM1; SMAD6; ZNF652; FOXF1; SMAD7; ZNF83; MED24; HOXA5; GABPB1; TOX; HMG20B; BACH2; CUX1; MAFF; TP63; BHLHE40; RBBP8; LITAF; IFI16; CHD7; GTF2IRD1; ZSCAN18; TERF2; ETS1; ZIC1; SOX11; ERBB2; BAZ1A; CD3D; KLF9; PBX3; NR1H2; HES1; BTG1; PITX1; MSX1; EGR3; ELF5; CCNA2; TCEA2
Down-regulation	76	TRIB3; HDAC4; ZSCAN5A; TFAP2C; UBE2B; SMARCA2; ZNF536; SOX12; NFE2L1; ZNF443; MAFB; E2F8; LMCD1; VDR; PQBP1; CHAF1B; EGR2; SMAD2; MED15; ZNF510; TEAD4; BACH1; OSR2; MEOX1; CTBP2; NR4A3; ZNF410; ZNF532; ZFHX4; NCOR2; MTDH; ATF7IP; TGFB1I1; ERF; ZNF593; PIAS2; ZBTB18; IRF5; SAP30; ZNF184; SIM2; USP22; MITF; USP16; NR1H4; CHD4; KLF10; BASP1; ZBED2; KAT2B; RUNX3; CREBL2; TBL1XR1; WWC1; ELF3; ELF1; HOXC6; TFCP2L1; TFEC; SPEN; NR0B1; ARID5B; TWIST1; BHLHE41; ARID4B; ID3; NFIB; GATA2; ZMYM2; MYRF; AEBP1; ZNF589; EMX2; RELB; PEG3; TXNIP