Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63022	Xylazine	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	189	EGR2; HOXA10; IRF8; ZNF623; DDX17; NCOA1; ZNF236; TFAP2C; FOXC1; BRCA1; LZTR1; PMF1; HOXC8; MYOD1; ZNF74; KAT2B; HOXA1; TSG101; ZBTB44; SERTAD2; RXRA; GATA3; SOX13; TLE4; ZNF112; TBX19; IRF4; HOXA11; MYF6; KLF4; MAFB; ZEB1; MAFK; HMG20A; BLZF1; UBE2L3; CBX4; SIX3; TBX1; ZBTB25; ZNF787; ATN1; ASCL1; LMCD1; TERF1; NRBF2; ZNF45; FOXN3; PAWR; CDK7; RERE; SOX4; ID4; THAP7; GMNN; VGLL4; FOXL2; OVOL1; ZBTB39; KDM5D; HIC2; ZBTB6; KLF10; CDX1; ZNF227; ZFP36L2; BARX2; BCL6; PDLIM1; SMARCC2; POU2F1; MYCL; RORA; TP63; ZNF764; PSMC3; PITX2; CREB3L1; ZBTB16; BATF; NCOA3; EP300; CDYL; PAX6; TBX2; TCF21; MED7; PGR; ZSCAN32; CDK8; TAF5; HDAC11; MMS19; RBFOX2; CIZ1; MEF2A; ZNF211; PPP1R13L; SP140; WT1; ZNF93; ZBTB20; ZKSCAN7; WNT4; ARID1A; ZNF248; TBPL1; SOHLH2; HMGXB4; GATA6; MSC; SMAD6; BCL10; MAF; IFI16; SMAD2; PLAGL2; THAP10; ZBTB43; FOXO1; BACH2; ZNF350; WWTR1; IRF1; CTR9; ZNF83; ZNF226; PBX3; TCEB2; ZNF202; TULP4; TRIM22; SSBP2; MEIS2; IRF7; JARID2; TAF10; HSF2; BHLHE40; HEY1; SPDEF; ZFP36L1; LHX3; CBX7; LITAF; HMG20B; MNAT1; GATA2; LYL1; TCF7L2; GLI2; EDF1; PLAGL1; BLM; ELF5; SOX10; ENO1; BIRC2; EN1; ZNF552; ZNF107; MEF2C; BNC2; CTBP2; JUP; ZNF589; ARID4B; HOXD3; MNDA; ATF6; ZFPM2; PSIP1; MEOX2; DNMT3B; IRF6; TOX; BHLHE41; NR1H2; HHEX; ZMIZ1; SCAND1; ID2; MLXIP; TOX3; HOXA5; NCOA4; CEBPD; SHOX2; ID1
Down-regulation	191	CCNH; MGA; SAFB2; SMARCA5; ZNF512B; SREBF1; FOXO3; BRD8; HMGB2; NCOR1; CCDC59; SFPQ; EED; SCMH1; MLXIPL; RYBP; SUPT6H; HIPK2; SAFB; ZNF10; DNMT1; ZFP69B; TLE1; MEIS1; CIC; FUBP1; ZNF165; PA2G4; NFYA; TSC22D1; ZNF140; ORC2; HNRNPD; NKX3-1; KLF2; MTDH; CCNC; NR1D2; RBM14; PNRC1; SIN3B; KDM4C; HDAC7; CCNA2; PRPF6; ZNF544; CERS6; BANP; TRIP6; RNF10; ZZZ3; ZNF467; RUVBL1; SMAD4; UIMC1; ING1; ZBED2; ARL2BP; SUPT4H1; TFAM; YWHAB; NFKBIB; CBX5; PQBP1; ING3; PROX1; POU4F2; MYT1L; WHSC1; PHF8; TCERG1; STAT5A; CHD1; MED12; RFX5; HIRA; KAT2A; DEK; AFF4; CNOT1; TCEA2; MED1; CNBP; ESR1; ARNTL; NEDD8; STAT5B; SAP30; PTTG1; RLF; HMGN3; RBPJ; CTBP1; POU3F2; PHF1; PRMT2; ZMIZ2; HMGA2; TFDP1; ZNF84; CREB3; MTF2; TOB1; NR0B2; NKX2-2; PFDN5; EYA2; TFDP2; USP22; RAD21; GTF2IRD1; SSX1; ZNF273; HIPK1; CRY1; SUMO1; NFAT5; SF1; ARID5B; ZNF532; ZNF692; SSRP1; TCF25; AFF1; HDAC2; CLOCK; TGIF1; NPM1; TGIF2; KLF7; NFKB1; HMBOX1; TOPORS; CBX6; NRIP1; VDR; SMAD1; PITX1; PRKDC; MYCN; ETS1; HOXB3; ZNF117; MED23; JUND; SOX9; RHOA; TRIM16; MAX; BAZ2B; DNAJC1; HIPK3; DDIT3; BAZ1A; HMGA1; NR0B1; SMAD3; ELF1; FOXM1; HSBP1; EHMT2; TERF2; MKL2; ATF3; SPEN; MYCBP; TAF9B; ZNF131; HTATIP2; ETS2; NANOG; NFE2L2; SATB1; FOXO4; PEG3; RAN; LOXL2; CITED2; SP3; ZSCAN18; FOSL2; BRD2; ZMYND8; ENY2; NEUROD1; NR3C1; ZNF721; KAT6B; HES1; AEBP1; EGR1