Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63006	Thiotepa	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	143	HMGA2; ERBB4; NHLH2; ZNF232; ZNF91; MYT1; GFI1B; CAMTA1; ZNF415; ASCL1; TCF7L1; ACTL6B; VGLL1; CHD7; ID4; NFATC3; ING4; L3MBTL1; PLAG1; WDR77; RBBP8; ZNF334; ZNF93; WNT4; KLF1; BCL11A; SOX17; YEATS4; GATA1; INSM1; ZNF667; XRCC6; IRF4; PSMC3IP; TCF7L2; ZNF675; VPS72; ARID3A; FOXO1; FUBP1; GATA3; CREB3L2; SOX13; ZIC3; NFE2; PBX3; NR4A2; SIX3; ZNF492; ZFHX3; SMARCA1; TAL1; HOXB5; ISL1; BRD7; MXI1; NKX2-1; CBFA2T2; IRF8; CERS4; ZSCAN18; SERTAD2; SP100; MEIS2; ZNF516; ST18; TBX3; NFATC4; CUX2; ZNF165; MEOX2; ZKSCAN7; GATA6; ZNF83; PSMC3; FOXC1; NR0B2; ZNF331; CEBPD; BACH2; MYBL2; TAF4; SALL1; TOX3; INSR; DACH1; ZNF107; FOXA1; ZBTB16; SOX11; HINFP; FLI1; CDK2; HES1; NR2F1; ZNF266; ZNF43; ZNF350; HDAC9; IFI16; PBX1; MYCL; ZMYND8; ZNF85; SNAI2; IRF6; HHEX; HMGB3; DLX2; SOX10; HOXB2; IRF9; AEBP1; TFAP2A; RNF138; PKNOX2; CBFA2T3; PHF20; CRYM; TOX; TSC22D2; ZBED2; SHOX2; ZNF423; CITED1; ZFPM2; MYB; HEY2; ATF3; ZNF589; NFE2L3; MNDA; ETS1; HIC2; NEUROD1; KLF13; TCEA2; JUP; PEG3; ESR1; ERG; POU2AF1; LEF1
Down-regulation	132	PARP1; USF2; TSC22D3; RNF10; SMARCA2; ZBTB38; EZH2; TRIP6; CEBPA; TRIM28; POU4F1; RBPJ; SAP30; NFKBIA; TRIM32; BIRC2; DDX54; ZNF576; ZMIZ2; EMX2; ELK1; NFE2L1; PCBD1; ZNF672; ORC2; ZBED4; KAT7; CIC; GTF3A; ERF; CCNA2; TRIM16; PRMT2; MITF; CCNC; NEDD8; CENPB; DNAJC1; MLX; NR1H3; GTF2I; MYC; PPARG; SAP18; ZNF148; MED15; ZNF189; NONO; RBBP4; NELFB; NCOA4; CREBZF; MAGED1; THAP11; DR1; SREBF1; MTDH; SMAD3; SMAD6; HLTF; MZF1; SMARCA5; MED6; ZNF146; KLF2; SLC2A4RG; ELF3; MAFB; VGLL4; AFF1; YAP1; ING1; BMI1; TGFB1; MYCBP; BRPF1; TP53; PIAS2; CREG1; ID2; PRRX1; RUNX3; ZZZ3; CASZ1; HOXB7; FHL2; ATF7IP; EDF1; ING2; TLE1; PSPC1; ELF1; ELK3; KLF6; PSIP1; MAX; ZNF281; MYRF; NFAT5; NPM1; REPIN1; KAT2B; RUVBL2; NKX3-1; RCOR1; BCL3; ZMIZ1; SFMBT1; HLF; CITED2; DDX5; YBX1; TCEA1; BHLHE41; ENO1; HOXC6; ERBB2; NRBF2; ATF6; TBX2; KLF9; RELB; ZMYM2; RFX5; EGR3; TWIST1; NR0B1; JARID2; ETS2; KAT6B; FLNA; MNAT1