Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID63005	Harpagoside	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	122	EGR2; HDAC6; ZNF419; ZBTB38; CARF; PLAG1; ZNF623; HMG20A; CTNNB1; RUNX1; SMARCC1; NRBF2; DDX17; NCOA3; ZEB2; SOX2; SUPT7L; MED7; NKX3-1; ZNF134; MED13; CRY1; STAT5A; POU4F2; STAT5B; TCF7L1; L3MBTL1; ZNF24; CXXC1; POU4F1; LIMD1; MED1; AHR; ARNTL; TMF1; BLZF1; KDM5A; BPTF; MZF1; PBRM1; BRIP1; LMCD1; CERS4; ZNF264; NR1D2; STAT4; ZNF302; EYA1; TAF7; ZNF224; ZNF532; ZNF667; ZNF12; ZNF593; ENO1; PDLIM1; FOXE1; CHD8; HOXA5; ZNF274; BTG1; ZNF131; TFDP1; ZNF426; MDM4; BATF3; THAP10; TOPORS; HIRA; BCL11B; MBD4; SOX11; FOXN3; PSIP1; FOSL1; CBX5; SMAD2; CD3D; MEIS1; ZNF551; TCERG1; MAF; ETS1; ELF5; MYBL1; RAN; BASP1; TCF7; ASCL1; SIM2; ZIC1; ZNF165; FOXC1; PTRF; PLAGL2; TBX2; ZNF652; BMI1; HIPK3; TCEB2; SNAI2; SCAND1; TCF4; TOX; KAT6B; FOXO4; SIX2; NR1H2; MED24; PLAGL1; BNC2; CARHSP1; BHLHE41; CEBPB; SIX1; MEIS2; CEBPD; NFE2L2; TCEA2; CCNA2; ID1; ZFPM2
Down-regulation	133	MYCBP; SCMH1; HIVEP1; E2F8; CHAF1B; MED17; FOXF1; ID3; NFYC; HIVEP2; CREBZF; THAP4; HOXB6; CDYL; DDX54; HOXB2; ETV4; GTF3A; AFF1; CCNH; HMGB2; TOB1; MED4; CEBPA; MYCL; RREB1; RFX5; NPAT; CCNE1; YAP1; SRF; BCL11A; PA2G4; TDP2; NFE2L1; HOXD10; RNF111; UBE2B; EMX2; OSR2; GMNN; ZEB1; EP300; DLX2; CREB3L2; USP16; PAX5; ZMYND8; ATF7IP; ZSCAN18; E4F1; PIAS1; SPDEF; EGR3; BARX1; FOXK2; NCOA2; PHF1; URI1; SLC2A4RG; PBX2; CBX7; TAF9; NRIP1; SMARCA5; NFKB1; PCGF2; CASZ1; CHD4; CREBL2; ESR1; ZNF217; TBP; IRF7; MAFB; SP100; CNOT3; TAF6; ZNF91; RLF; DEAF1; SP2; MAZ; ZBTB18; ZMIZ2; BIRC2; ELF1; SSBP2; CTBP2; SFMBT1; CNBP; BRD4; LEF1; NFIC; RNF6; NR3C2; TRIM22; ARID4B; HLTF; DLX5; SFPQ; YBX3; HOXD1; ATF3; ZNF331; BCL3; TOX3; TGFB1I1; VDR; HMGB1; RELA; ASH2L; HDAC2; MNDA; CRYM; JUND; HOXB7; GATA2; CHD7; TCF7L2; RBBP8; DMTF1; HOXD3; ID4; NR4A2; NR4A1; LOXL2; KLF13; MYRF; TXNIP; NR3C1; PBX3; RELB