Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62965	Mexiletine	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	85	IKZF1; HDAC6; GATA3; IRF8; NFATC3; ZBTB44; HIVEP1; ZNF74; SSBP3; REL; MYCL; CEBPE; FOXO1; ECD; FOXI1; CNOT6; SALL2; PSMC3; ESR1; HOXC11; FOXL2; TFAP2C; ARID3B; IFI16; KAT2A; OSR2; MBD4; MNDA; CALR; ATF6; ZNF264; CBFA2T3; ERBB4; BCL11A; TCF3; SSRP1; LITAF; ZNF331; RREB1; ZNF274; NCOA3; TRAK1; ZNF224; TRPS1; PRMT2; SF1; AR; HOXC10; ZNF32; APEX1; MSX1; NR4A3; ACTL6A; ZEB1; MYB; MYBL1; NAB2; TRIM22; SNAI2; ASCL1; NR4A2; ZNF394; ZBTB20; GATA2; CREB3L2; TP63; SOX17; PGR; BLM; JUP; EMX2; ZNF107; TOX3; CD3D; TRIM29; BNC2; IRF7; ZNF652; HDAC9; CEBPB; FOSB; ZBTB16; NFE2L2; HOXC6; TCEA2
Down-regulation	92	HNRNPD; SAP30; CEBPG; FOXD1; ID3; DR1; MED4; SOX9; CHD1; ZBTB38; PEX2; ARNTL; ASXL1; NLK; SMARCA5; PAX6; KLF10; TEAD1; C1D; VEZF1; MEIS1; TOB1; HCFC2; MNT; CRY1; RFX7; ELF2; SMARCE1; SAFB2; RNF6; TGFB1I1; MAGED1; HOXA7; FOXF1; ARID4A; ELF1; PIAS2; SMAD5; FOXF2; TDP2; GTF2I; NR2C1; HMGB2; VDR; ZBTB18; TLE4; PDLIM1; ZBED2; ELK3; MEF2C; BCL6; DDIT3; MYCN; ING2; TRIM32; BATF3; NPAS2; TBPL1; MEOX2; ZFHX4; TCEB2; ENY2; SP3; WWTR1; ELF3; TBL1XR1; SSBP2; ELF4; ARID4B; HMGN3; TGIF1; SATB2; WWC1; ZMYM2; CTBP2; NKX3-1; TCEA1; RNF14; TAF9B; TSC22D1; HOXA5; ZMIZ1; RELB; AEBP1; PITX1; ZFP36L1; PBX3; LEF1; BHLHE41; BASP1; PEG3; TXNIP