Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62899	Fulvestrant	GSE92742	PHH	Human	24h	10uM	EID0352

Response Information :

Types	Number	Response transcription factors
Up-regulation	174	IKZF1; SMARCA1; SUB1; HOXB5; SSBP3; PLAG1; SUPT6H; PEX14; SALL1; BTF3; BRD3; HDAC5; BRF2; MYCL; ZNF232; ZNF771; HIF3A; PRDM1; CUX2; KLF12; ERCC3; DLX2; HOXA11; ZNF671; HOXB6; STAT4; MKL2; ZFP36L2; GTF2F1; HLX; SIRT2; JUP; NKX2-1; CREG1; TCF25; TP53; ZNF140; PCGF3; ZFX; FOXF1; DBP; FOXF2; ABT1; ZBTB39; PA2G4; PAX9; IRF6; CTBP1; ZNF516; IRF2; BATF3; ATOH1; EYA1; LITAF; LHX2; FOXL2; GABPA; ETV4; IRF4; PIAS4; CHD8; SMARCD1; ETV5; DRAP1; HOXB2; ZNF423; NOC2L; SIX2; MYCN; HMG20B; HDAC4; PMF1; PEG3; ZNF580; CHD3; HMGB3; ZKSCAN8; PITX1; ZNF556; TGFB1I1; MEIS2; ESR1; NFE2; MTA1; ZNF239; TXNIP; KDM5B; HR; POU2F2; NHLH2; SREBF2; PCGF1; WNT4; STAT6; CDIP1; ZNF536; SPDEF; RBL2; ZNF195; MSX1; LHX3; BARX1; ETV1; SIAH2; SIX6; IRF9; MXI1; OSR2; SOX17; TAL1; MXD4; RING1; PITX2; RFXANK; BCL11A; HMGA1; FOXI1; RBBP8; HIPK3; NKX2-2; SETDB1; SCAND1; ZNF552; EMX2; TTF1; SNAI1; NAB2; ZNF8; CD3D; HDGF; ARID4B; SMAD7; FOXM1; NFYC; RXRA; HES1; BACH2; ZFP36L1; ZNF85; PCGF2; ZMIZ1; CRYM; PIAS3; ZNF211; IFI16; TGFB1; SKI; PLAGL2; NR1H2; ZNF217; FOXN3; KLF11; HOXD3; KLF7; PBX1; GLI2; CREB3L2; MECOM; RCOR1; TCEA2; SHOX2; WWTR1; MEIS1; FLNA; MYRF; GATA6; ZNF43; ZBTB16; CEBPB; ZIC1; ZNF589; POU2AF1; WT1; SOX11
Down-regulation	162	KLF4; BBX; EZH2; POU4F1; THAP11; ZNF44; TBL1XR1; USP22; HNRNPD; CCNA2; NFYB; BIRC2; CEBPG; TAF1; DNAJC2; ING2; BHLHE41; MED4; DNMT1; ZZZ3; MTDH; ZEB2; ZNF562; TSC22D3; PATZ1; REPIN1; ZNF12; ZBED4; ZNF146; SREBF1; MTF2; ENY2; HIF1A; IKBKAP; REL; CCNC; NR1I2; TFAM; ATF7IP; HIRA; ARNTL; CHD1; WWC1; MYCBP; ZBTB38; ORC2; ZNF148; ZNF443; RNF6; ZNF573; ZNF224; FOSB; SMARCA5; HDAC1; CRY1; UBTF; INSM1; UBE2B; RNF14; CREBL2; DR1; PURA; NR1D2; ING3; PRRX1; GTF3A; ZNF24; SFPQ; AEBP1; SOX5; ZBTB1; RORA; TAF12; MITF; ZBTB20; BMI1; NR3C2; EED; NCOA4; MED1; NRIP1; ZNF165; JAK2; FOS; TAF7; ARNTL2; PMS1; HIC2; COPS5; BTAF1; EGR3; ZNF23; CITED2; ZNF302; HMGN3; KDM2A; AHR; KLF2; ZNF160; MBD4; DDIT3; TCEA1; TCERG1; ZNF654; DDX5; VDR; ZNF665; ZNF721; ZNF189; NR1H4; NFAT5; TFEC; NR4A1; MED13; ELF5; PRKDC; XBP1; ZNF652; ZNF430; NFIL3; TCF4; RBBP4; MDM2; HOXA5; YBX1; ATF3; ZFPM2; TCF7; TOB1; ZNF266; NFIB; ZNF551; TSC22D1; HLTF; TAF9; MEF2C; BRD8; TRIM22; NRBF2; DACH1; YWHAB; ENO1; MNDA; TLE1; HOXC6; COPS2; ABL1; TAF1D; ZMYM2; NR4A2; RNF138; ID2; DNAJC1; LOXL2; HOXB7; BRD4; BASP1; FOSL2; KDM5D; ZBED2; LEF1; NANOG