Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62874	Betahistine	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	TSC22D3; TDP2; FOXG1; HIVEP1; VPS72; POLR3C; ETV7; BCL11A; IRF7; DDIT3; FOXD1; E2F5; GMNN; ZSCAN18; ZMYM2; REL; PHF20; ZNF529; COPS5; TBL1XR1; CBFA2T3; TFAP2A; ACTL6A; DMTF1; NCOA1; E2F8; MKL2; SSBP2; INSM1; PHIP; SIX3; KLF13; CREB1; DBP; ZNF33B; ZBTB16; HDAC9; BACH1; JARID2; NAB1; KLF9; CREM; TERF1; SPIB; CDK2; MYBL1; KAT2B; FOXF1; PRRX2; CUX2; GTF3A; DAXX; SOX9; ZEB1; ATF3; ELF4; ZIC1; ZMIZ1; HSBP1; SMAD3; TFEC; HEY1; ID4; KDM5D; TSC22D1; CCNC; LOXL2; SNAI2; HMGA2; HES1
Down-regulation	83	TGFB1; INSR; HCFC2; TGFB1I1; ZBTB43; ZEB2; ZSCAN31; HSF2; SKI; MLXIP; FOSL1; RNF10; PHF8; AGO2; ZNF410; ELF1; NFKBIA; PRRX1; MAX; ZNF423; BHLHE41; TXNIP; EGR2; KAT6A; ESR1; TFCP2L1; REXO4; SOX5; CREB3L1; KAT5; ZNF189; HMGA1; HDAC4; TRIM32; FOXA1; CHD1; TLE4; MSX1; EDF1; HDAC2; CITED2; CRY1; AFF1; SMARCA2; MED24; SIAH2; FLNA; SIX1; FHL2; PURA; ERBB2; NFIL3; YBX3; TBL1X; KLF2; PEG3; ZBTB38; HDAC1; TSC22D2; AEBP1; OSR2; TRIM28; ARID4B; MDM2; RFX5; YBX1; NR3C2; MEF2C; MED1; CHD7; STAT1; PBX3; NR2F2; DACH1; MXI1; SPEN; PSIP1; SATB1; NKX3-1; HMG20B; EMX2; BASP1; RELB