Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62870	Pyrimethamine	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	UBE2B; HOXA1; MEIS1; JUP; KLF11; HMGB1; RNF141; PPARGC1A; ZNF200; NFATC3; GMNN; E2F6; ZZZ3; CNOT1; LEF1; NR4A1; MYRF; JUNB; DLX5; DLX2; KLF2; SSX1; TERF2; FOXO1; AFF1; ITGB3BP; POU4F1; SP140L; TLE4; ZBTB16; TBL1XR1; ZMIZ1; KLF10; GABPB1; TCF21; FOXG1; SMAD1; HMG20B; CBX5; FOXN3; PFDN5; SMAD3; ID3; RREB1; ID2; FLNA; NR0B1; PAX5; TCEA1; SMARCA4; FHL2; TGIF1; FOXD1; ATF3; DNMT3B; IKBKAP; SIAH2; ID1; TP63; TSC22D1; TOB1; TOX3; NKX3-1; TBL1X; NRIP1; NR4A2; HOXB7; MYBL1; USP22; CCNA2; TBX2; CDK7
Down-regulation	66	CERS6; SUZ12; TGFB1I1; CRK; RUNX3; GTF2I; SP100; EGR2; ZNF329; ZIC1; SOX11; ASCL1; MYCL; IRF4; SOX10; MDM4; ZNF91; GATA6; RFX7; TRIM22; SIX1; PTTG1; ZNF444; HSF2; INSR; NR1D2; IRF7; IRF9; RERE; ZBED2; TCFL5; CITED1; PITX2; SUB1; RSF1; ZNF589; HIPK3; ARID4B; PRRX1; DRAP1; PDLIM1; NAB1; ZNF217; HMGA1; ZNF512B; ZNF432; RLF; TRIP6; SHOX2; GATA3; FOXE1; HEY1; FOS; ZBTB38; NR1H2; ERBB2; KAT6B; MSX1; PSIP1; DACH1; NFAT5; STAT5B; TRPS1; WT1; BASP1; KDM5D