Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID62868	Tolbutamide	GSE92742	PHH	Human	24h	10uM	EID0351

Response Information :

Types	Number	Response transcription factors
Up-regulation	156	TCFL5; SERTAD2; DLX4; HOXC10; TRAK1; MTA1; ZNF34; GATA6; PAX5; HBP1; INSM1; HOXC6; GTF2I; IKZF5; CENPF; ZNF302; PRRX1; NR2C1; EGR1; GABPA; AES; E2F5; VAX2; ZNF536; TSC22D3; DBP; ZEB2; PCGF3; HOXA1; DDX17; BCL11A; ZKSCAN7; RBFOX2; HLX; BCL10; SMAD4; ZNF7; BLM; CDYL; HMGXB4; TGFB1; PITX2; LITAF; HOXD3; SSX1; SSBP2; CREB3L1; ZNF652; SIX1; ZNF253; ATF2; HMBOX1; ZNF665; ZIC1; SMAD6; HLTF; MZF1; PBX3; ZNF721; MAF; WHSC1; FOSL1; ZNF587; PPP1R13L; RBBP4; ZNF160; ZNF93; PPARD; REL; SOX11; HMG20B; SNAI2; IL16; IRF8; TAF10; CBX7; SMAD7; IRF1; ZNF146; BHLHE40; APEX1; IRF2; CREB5; RHOA; ZFHX4; IRF4; MSX1; MECOM; EP300; HOXB13; TRIM16; BACH1; BACH2; HIVEP1; XRCC6; HOXD1; EWSR1; SATB1; TBL1XR1; TWIST1; MED24; ZNF43; ZNF14; TAF5; TCF7; EBF2; KLF2; CUX1; STAT1; FOXD1; POU2AF1; TCF3; ARID4B; ZNF23; BIRC2; TXNIP; PHF20; MYRF; MYCL; MEOX2; RUVBL2; YAP1; ITGB3BP; JARID2; SMARCA1; POU4F1; ZNF611; MED6; NR1D2; PTTG1; SP140L; TCF4; PLAGL1; ZNF623; ZNF195; CTR9; RXRA; EZH2; SMAD3; ZNF264; THAP11; SOX4; NONO; REPIN1; HIC2; CHD7; CALR; TULP4; NRIP1; WT1; ABL1; TCEA2; PIR; MYBL1; ID1; KDM5D
Down-regulation	146	FOXJ1; HMGB3; PROX1; ELF1; SMARCA2; NKRF; ZNF12; FOXN2; NFIB; TFAM; STAT5A; HMGXB3; POLR2A; NCOA2; CCNH; ETV4; BRD4; TFDP1; CEBPD; NR4A1; RNF111; POLR3C; PPARGC1A; EGR4; SP4; ELF5; HOXB6; NR1H4; ZNF148; ATF3; RFX7; TGFB1I1; NR5A2; TCERG1; JAK2; LHX2; KLF1; SALL1; SOX3; TRIM29; TRIB3; AR; NR1H3; FOXJ2; HMGA1; INSR; ID2; WWC1; HIPK1; E2F8; TAL1; E2F3; CNOT1; SOX9; CBFB; ZNF91; ERF; THAP4; ZMYM2; FOXG1; CTBP2; ZMIZ2; TFCP2L1; LPIN2; MDM4; FOXA1; GTF2A2; KLF10; RORA; NR1H2; ELF3; RNF6; TFAP2C; ADNP2; ETV5; TSC22D1; KMT2A; NFIL3; GATAD2A; ARL2BP; BRD2; KLF13; CUX2; LDB1; ZNF281; RNF138; MYBL2; FLNA; WDR77; ARID5B; NPAT; IRF6; FHL5; MEIS1; SMAD1; ASCL1; NR3C2; CEBPG; PSIP1; BAZ1A; CAMTA2; EMX2; LIN28A; HLF; YBX3; TGIF1; OLIG2; FOSL2; TRIP6; ELF4; SAP30; HOXB2; ZNF512B; KAT6B; TBL1X; ZBTB16; ZNF140; ERBB2; SOHLH2; DAXX; TOB1; NANOG; PRPF6; TCF7L2; TFEC; HES1; FOXC1; SIAH2; ZBTB20; SPEN; HMGA2; ENO1; ZNF331; NFAT5; NR4A2; KLF6; TOX3; MXI1; NR2F1; ESR1; PEG3; GATA2; USP22; HTATIP2; STAT5B; RELB